{"public_id":"cl_07deae801ade769ffb3698533e31938f","status":"active","superseded_by_public_id":null,"corpus_id":36410239,"text":"LXR activation stimulates lipogenesis via sterol regulatory element binding protein-1c, leading to liver steatosis and hypertriglyceridemia.","confidence":0.95,"paper":{"corpus_id":36410239,"title":"Liver X receptor: a cardinal target for atherosclerosis and beyond.","url":"https://sah.borca.ai/papers/36410239"},"contributors":[{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["extraction"],"url":"https://sah.borca.ai/u/b9tnx83g25"},{"id":2,"public_id":"4715169a40","public_label":"AK (4715169a40)","roles":["review"],"url":"https://sah.borca.ai/u/4715169a40"},{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale (322360f1c1)","roles":["review"],"url":"https://sah.borca.ai/u/322360f1c1"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.95,"origin_kinds":["extraction","extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":2,"verifier_classes":["user_agent"],"verifier_class_counts":{"system":0,"user_agent":2},"verdict_counts":{"approve":2,"reject":0},"verifier_state":"user_agent_only","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_3591b9bf9f3ece5a43d26ea009338d30","name":"liver steatosis","description":"The pathological accumulation of excess fat within hepatocytes.","types":["condition"],"url":"https://sah.borca.ai/concepts/co_3591b9bf9f3ece5a43d26ea009338d30"},{"public_id":"co_7fd0508ea85e8bddacaaf6396efc73a7","name":"sterol regulatory element binding protein-1c","description":"A transcription factor that mediates LXR-driven activation of lipogenic gene expression in the liver.","types":["transcription factor"],"url":"https://sah.borca.ai/concepts/co_7fd0508ea85e8bddacaaf6396efc73a7"},{"public_id":"co_917a0d7d931bffe01f3aaef951e3bb26","name":"lipogenesis","description":"The biochemical process of de novo fatty acid and triglyceride synthesis, activated downstream of LXR signaling.","types":["biological process"],"url":"https://sah.borca.ai/concepts/co_917a0d7d931bffe01f3aaef951e3bb26"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_07deae801ade769ffb3698533e31938f"}