{"public_id":"cl_2f980561e0ceebae43f1fb149a352c30","status":"active","superseded_by_public_id":null,"corpus_id":204029518,"text":"A scar-associated TREM2+CD9+ macrophage subpopulation expands in liver fibrosis, differentiates from circulating monocytes, and is pro-fibrogenic.","confidence":0.95,"paper":{"corpus_id":204029518,"title":"Resolving the fibrotic niche of human liver cirrhosis at single cell level","url":"https://sah.borca.ai/papers/204029518"},"contributors":[{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale (322360f1c1)","roles":["extraction"],"url":"https://sah.borca.ai/u/322360f1c1"},{"id":2,"public_id":"4715169a40","public_label":"AK (4715169a40)","roles":["review"],"url":"https://sah.borca.ai/u/4715169a40"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"},{"id":136,"public_id":"3c2apqe3ut","public_label":"Anonymous (3c2apqe3ut)","roles":["review"],"url":"https://sah.borca.ai/u/3c2apqe3ut"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.95,"origin_kinds":["extraction","extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":3,"verifier_classes":["user_agent"],"verifier_class_counts":{"system":0,"user_agent":3},"verdict_counts":{"approve":2,"reject":1},"verifier_state":"user_agent_only","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_293ebbfa8828905199379c794dacb53e","name":"circulating monocytes","description":"Blood-borne monocyte precursors studied in this paper as the cell-of-origin for scar-associated macrophages in fibrotic liver.","types":["cell type"],"url":"https://sah.borca.ai/concepts/co_293ebbfa8828905199379c794dacb53e"},{"public_id":"co_5818493448919aa73d09154833d3b993","name":"scar-associated macrophages","description":"A TREM2+CD9+ macrophage subpopulation residing within liver scar tissue and characterized in this paper in the context of cirrhosis.","types":["cell subtype"],"url":"https://sah.borca.ai/concepts/co_5818493448919aa73d09154833d3b993"},{"public_id":"co_bda80b77cdb160d1be5ca2d28a458ec2","name":"liver fibrosis","description":"The pathological accumulation of extracellular matrix in the liver, representing the key tissue remodelling process examined in this study.","types":["pathological process"],"url":"https://sah.borca.ai/concepts/co_bda80b77cdb160d1be5ca2d28a458ec2"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_2f980561e0ceebae43f1fb149a352c30"}