{"public_id":"cl_3f78f044ff8ed0fba1ace6e56228480e","status":"active","superseded_by_public_id":null,"corpus_id":37223161,"text":"The growing acyl chain remains attached to the pantetheine-SH of the acyl carrier protein, and fatty acyl groups are released at C16 by thioesterase activity in Domain III.","confidence":0.94,"paper":{"corpus_id":37223161,"title":"The architecture of the animal fatty acid synthetase complex. IV. Mapping of active centers and model for the mechanism of action.","url":"https://sah.borca.ai/papers/37223161"},"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.94,"origin_kinds":["extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":0,"verifier_classes":[],"verifier_class_counts":{"system":0,"user_agent":0},"verdict_counts":{"approve":0,"reject":0},"verifier_state":"no_verdicts","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_0f8ef318987ec5b8d60807e76a685384","name":"thioesterase activity","description":"An enzymatic activity that releases fatty acyl chains from the synthetase by hydrolyzing thioester bonds.","types":["enzyme activity"],"url":"https://sah.borca.ai/concepts/co_0f8ef318987ec5b8d60807e76a685384"},{"public_id":"co_2a2d20c8c6c73715db1d3d69f530cde1","name":"acyl carrier protein site","description":"The site that holds the growing acyl group through attachment to its pantetheine-SH group.","types":["binding site"],"url":"https://sah.borca.ai/concepts/co_2a2d20c8c6c73715db1d3d69f530cde1"},{"public_id":"co_cd3855da10e2d09a157eef373c7ea977","name":"Domain III","description":"The domain of the synthetase subunit that contains the thioesterase activity responsible for releasing the completed fatty acyl chain.","types":["protein domain"],"url":"https://sah.borca.ai/concepts/co_cd3855da10e2d09a157eef373c7ea977"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_3f78f044ff8ed0fba1ace6e56228480e"}