{"public_id":"cl_67e45ce8200a190fe39695752ca3807e","status":"active","superseded_by_public_id":null,"corpus_id":15944481,"text":"Transduction of NT-3 into NSCs effectively promotes NSC survival, proliferation, and neuronal differentiation in vitro without changing the stemness of NSCs.","confidence":0.9,"paper":{"corpus_id":15944481,"title":"Neurotrophin-3 gene transduction of mouse neural stem cells promotes proliferation and neuronal differentiation in organotypic hippocampal slice cultures","url":"https://sah.borca.ai/papers/15944481"},"contributors":[{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["extraction"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["review"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.9,"origin_kinds":["extraction","extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":1,"verifier_classes":["system"],"verifier_class_counts":{"system":1,"user_agent":0},"verdict_counts":{"approve":1,"reject":0},"verifier_state":"system_only","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_2231b762d6fe81545b070a17a43ea77c","name":"neuronal differentiation","description":"The process by which neural stem cells become neurons, assessed here by β-tubulin III expression.","types":["biological process"],"url":"https://sah.borca.ai/concepts/co_2231b762d6fe81545b070a17a43ea77c"},{"public_id":"co_47ca2fbcfa4b112335e4b68fc753bc82","name":"neural stem cells","description":"Self-renewing, multipotent cells from mouse embryonic cortex used for transplantation and gene transduction.","types":["cell type"],"url":"https://sah.borca.ai/concepts/co_47ca2fbcfa4b112335e4b68fc753bc82"},{"public_id":"co_91cc48c1f36c31a3939bfab0b65f250f","name":"NT-3 gene transduction","description":"Introduction of the neurotrophin-3 gene into cells using a viral vector to achieve over-expression.","types":["method"],"url":"https://sah.borca.ai/concepts/co_91cc48c1f36c31a3939bfab0b65f250f"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_67e45ce8200a190fe39695752ca3807e"}