{"public_id":"cl_92aa34462c29556b66dab68154143f55","status":"active","superseded_by_public_id":null,"corpus_id":8940481,"text":"G protein-coupled receptors can use distinct endocytic pathways distinguishable by dynamin and β-arrestin, and β-arrestins act as adaptor proteins targeting receptors for dynamin-dependent endocytosis via clathrin-coated vesicles.","confidence":0.97,"paper":{"corpus_id":8940481,"title":"Dynamin and β-Arrestin Reveal Distinct Mechanisms for G Protein-coupled Receptor Internalization*","url":"https://sah.borca.ai/papers/8940481"},"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.97,"origin_kinds":["extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":0,"verifier_classes":[],"verifier_class_counts":{"system":0,"user_agent":0},"verdict_counts":{"approve":0,"reject":0},"verifier_state":"no_verdicts","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_770281c754913a4c9a7a69b6eebccf39","name":"β-arrestin","description":"A receptor-associated adaptor protein that links certain G protein-coupled receptors to endocytic machinery.","types":["adaptor protein"],"url":"https://sah.borca.ai/concepts/co_770281c754913a4c9a7a69b6eebccf39"},{"public_id":"co_added743e4eed309aec558b10e1a3000","name":"dynamin","description":"A GTPase involved in the formation and scission of clathrin-coated vesicles during endocytosis.","types":["protein","GTPase"],"url":"https://sah.borca.ai/concepts/co_added743e4eed309aec558b10e1a3000"},{"public_id":"co_fd238dee9660f0d67387e791edb0ef74","name":"G protein-coupled receptors","description":"A large family of cell-surface receptors that transmit extracellular signals through heterotrimeric G proteins.","types":["receptor family"],"url":"https://sah.borca.ai/concepts/co_fd238dee9660f0d67387e791edb0ef74"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_92aa34462c29556b66dab68154143f55"}