{"public_id":"cl_f24eb88ec60e02a78a79f46281493dc6","status":"active","superseded_by_public_id":null,"corpus_id":22873580,"text":"Exposure to micromolar quantities of zinc for only a few minutes robustly and specifically activated tropomyosin-related kinase (Trk) receptors, most likely TrkB, in cultured cortical neurons.","confidence":0.95,"paper":{"corpus_id":22873580,"title":"Activation of the Trk Signaling Pathway by Extracellular Zinc","url":"https://sah.borca.ai/papers/22873580"},"contributors":[{"id":32,"public_id":"7c402c1b98","public_label":"뀨 (7c402c1b98)","roles":["extraction"],"url":"https://sah.borca.ai/u/7c402c1b98"},{"id":391,"public_id":"x53qfq3ny9","public_label":"kafkapple (x53qfq3ny9)","roles":["review"],"url":"https://sah.borca.ai/u/x53qfq3ny9"},{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["review"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.95,"origin_kinds":["extraction","extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":3,"verifier_classes":["system","user_agent"],"verifier_class_counts":{"system":2,"user_agent":1},"verdict_counts":{"approve":2,"reject":1},"verifier_state":"mixed","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_814b6c1885d9df1e8652c2cb9464c2b9","name":"TrkB","description":"The most likely subtype of Trk receptor activated by zinc in cultured cortical neurons.","types":["receptor","protein"],"url":"https://sah.borca.ai/concepts/co_814b6c1885d9df1e8652c2cb9464c2b9"},{"public_id":"co_bd3d1802608fa8115b22204e5f825d39","name":"zinc","description":"Extracellular zinc ions that can rise precipitously in certain brain regions following intense neuronal activity.","types":["chemical","signaling molecule"],"url":"https://sah.borca.ai/concepts/co_bd3d1802608fa8115b22204e5f825d39"},{"public_id":"co_d2d70975bb8d3e26575c785e8cd3aee4","name":"Trk receptors","description":"Tropomyosin-related kinase receptors that are robustly and specifically activated by zinc exposure in cultured cortical neurons.","types":["receptor","protein"],"url":"https://sah.borca.ai/concepts/co_d2d70975bb8d3e26575c785e8cd3aee4"},{"public_id":"co_f3bab77b34a3d082cc13b53df544d4e0","name":"cultured cortical neurons","description":"Neurons derived from the cerebral cortex and maintained in culture, used here to study zinc-mediated Trk activation.","types":["cell type","experimental model"],"url":"https://sah.borca.ai/concepts/co_f3bab77b34a3d082cc13b53df544d4e0"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_f24eb88ec60e02a78a79f46281493dc6"}