{"public_id":"cl_fcd3211992729eada53a5713700af59f","status":"active","superseded_by_public_id":null,"corpus_id":37448366,"text":"Blocking protein C activation in vivo makes the response to lethal Escherichia coli more severe and converts the response to sublethal Escherichia coli into a lethal one.","confidence":0.96,"paper":{"corpus_id":37448366,"title":"Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon.","url":"https://sah.borca.ai/papers/37448366"},"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.96,"origin_kinds":["extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":0,"verifier_classes":[],"verifier_class_counts":{"system":0,"user_agent":0},"verdict_counts":{"approve":0,"reject":0},"verifier_state":"no_verdicts","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_54418aa62ff14d6dcf88e3f047cca505","name":"Escherichia coli","description":"A gram-negative bacterium used here as the septic challenge organism.","types":["organism","bacterium"],"url":"https://sah.borca.ai/concepts/co_54418aa62ff14d6dcf88e3f047cca505"},{"public_id":"co_c67ddd92a0339763553f648f2677ed66","name":"sublethal concentrations of Escherichia coli","description":"An Escherichia coli dose that does not cause death under normal conditions in the experiment.","types":["experimental condition"],"url":"https://sah.borca.ai/concepts/co_c67ddd92a0339763553f648f2677ed66"},{"public_id":"co_d49c7743d057d1690b4430fa03491564","name":"protein C activation","description":"The conversion of protein C into its activated anticoagulant form in vivo.","types":["biological process"],"url":"https://sah.borca.ai/concepts/co_d49c7743d057d1690b4430fa03491564"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_fcd3211992729eada53a5713700af59f"}