{"public_id":"cl_ff852e980c53d37f4f1f36508f14ee70","status":"active","superseded_by_public_id":null,"corpus_id":269702128,"text":"Selective activation of p53 remains a challenge because it must inhibit tumor growth without harming normal homeostasis.","confidence":0.88,"paper":{"corpus_id":269702128,"title":"Understanding the complexity of p53 in a new era of tumor suppression.","url":"https://sah.borca.ai/papers/269702128"},"contributors":[{"id":1,"public_id":"12632b8b5f","public_label":"Anonymous (12632b8b5f)","roles":["extraction"],"url":"https://sah.borca.ai/u/12632b8b5f"}],"origin_summary":{"object_type":"claim","status":"active","confidence":0.88,"origin_kinds":["extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":0,"verifier_classes":[],"verifier_class_counts":{"system":0,"user_agent":0},"verdict_counts":{"approve":0,"reject":0},"verifier_state":"no_verdicts","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","claim.status","claim.confidence"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"concepts":[{"public_id":"co_4281715486d1a2939457957fcc73850b","name":"tumor growth","description":"The proliferation and expansion of cancer cells.","types":["phenomenon"],"url":"https://sah.borca.ai/concepts/co_4281715486d1a2939457957fcc73850b"},{"public_id":"co_7aeb88e46adb664353e70bc551fe2d8f","name":"normal homeostasis","description":"The stable physiological state of normal tissues that should be preserved during therapy.","types":["physiological state"],"url":"https://sah.borca.ai/concepts/co_7aeb88e46adb664353e70bc551fe2d8f"},{"public_id":"co_b2667f6e9c4f3cced77927f737eb41b1","name":"p53 function","description":"The biological actions of p53 that can be activated or modulated for therapeutic purposes.","types":["molecular function"],"url":"https://sah.borca.ai/concepts/co_b2667f6e9c4f3cced77927f737eb41b1"}],"related_claims":[],"url":"https://sah.borca.ai/claims/cl_ff852e980c53d37f4f1f36508f14ee70"}