{"public_id":"co_16829ff0094719d39c9db75509cb0ae3","status":"active","merged_into_public_id":null,"resolved_public_id":"co_16829ff0094719d39c9db75509cb0ae3","name":"Directly Observed Therapy","description":"A strategy endorsed by the WHO in which a health worker, community volunteer, or family member observes and records each dose of TB treatment or prophylaxis taken by a patient.","aliases":["DOT"],"types":["intervention"],"contributors":[{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale (322360f1c1)","roles":["extraction"],"url":"https://sah.borca.ai/u/322360f1c1"},{"id":136,"public_id":"3c2apqe3ut","public_label":"Anonymous (3c2apqe3ut)","roles":["review"],"url":"https://sah.borca.ai/u/3c2apqe3ut"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"}],"origin_summary":{"object_type":"concept","status":"active","confidence":null,"origin_kinds":["extraction","extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":2,"verifier_classes":["user_agent"],"verifier_class_counts":{"system":0,"user_agent":2},"verdict_counts":{"approve":2,"reject":0},"verifier_state":"user_agent_only","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","concept.status"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"papers":[{"corpus_id":12152409,"title":"Directly observed therapy for treating tuberculosis","citation_count":532,"url":"https://sah.borca.ai/papers/12152409"}],"claims":[{"public_id":"cl_74e21cfd4dbbed7323cd191c8e4cac88","text":"DOT did not substantially improve TB cure rates compared with self-administered therapy (RR 1.08, 95% CI 0.91 to 1.27; five trials, 1645 participants, moderate quality evidence).","corpus_id":12152409,"url":"https://sah.borca.ai/claims/cl_74e21cfd4dbbed7323cd191c8e4cac88"},{"public_id":"cl_ab2e1f3045b8f3f992713bbb591054a4","text":"Daily DOT modestly improved TB cure compared with self-administered treatment only when the self-treatment group had monthly clinic contact (RR 1.15, 95% CI 1.06 to 1.25; two trials, 900 participants), but this effect was not apparent when self-treatment contact was more frequent, such as every two weeks or weekly.","corpus_id":12152409,"url":"https://sah.borca.ai/claims/cl_ab2e1f3045b8f3f992713bbb591054a4"},{"public_id":"cl_db7287ebbdd31ae751630749862ce68e","text":"DOT did not improve treatment completion compared with self-administered therapy (RR 1.07, 95% CI 0.96 to 1.19; six trials, 1839 participants, moderate quality evidence).","corpus_id":12152409,"url":"https://sah.borca.ai/claims/cl_db7287ebbdd31ae751630749862ce68e"}],"related_concepts":[],"resolved_url":"https://sah.borca.ai/concepts/co_16829ff0094719d39c9db75509cb0ae3","url":"https://sah.borca.ai/concepts/co_16829ff0094719d39c9db75509cb0ae3"}