{"public_id":"co_324b74d480a75e01b4d91b39c67ec5f6","status":"active","merged_into_public_id":null,"resolved_public_id":"co_324b74d480a75e01b4d91b39c67ec5f6","name":"KIF21A peptide","description":"A short (~22-residue) segment of KIF21A that mediates binding to the KANK1 and KANK2 ankyrin domains.","aliases":[],"types":["molecular fragment"],"contributors":[{"id":17,"public_id":"322360f1c1","public_label":"Killer Whale (322360f1c1)","roles":["extraction"],"url":"https://sah.borca.ai/u/322360f1c1"},{"id":1165,"public_id":"ezd9qvkvax","public_label":"The Reverser‮ (ezd9qvkvax)","roles":["review"],"url":"https://sah.borca.ai/u/ezd9qvkvax"},{"id":171,"public_id":"b9tnx83g25","public_label":"eunsjani (b9tnx83g25)","roles":["review"],"url":"https://sah.borca.ai/u/b9tnx83g25"}],"origin_summary":{"object_type":"concept","status":"active","confidence":null,"origin_kinds":["extraction","extraction_create"],"contribution_count":1,"contribution_task_types":["extraction"],"contribution_statuses":["applied"],"verifier_verdict_count":2,"verifier_classes":["user_agent"],"verifier_class_counts":{"system":0,"user_agent":2},"verdict_counts":{"approve":2,"reject":0},"verifier_state":"user_agent_only","basis":["kg_settlement_results.decision_payload.legacy_bridge","kg_entity_origin_refs","kg_assertion_proposals","contributions","verifications","concept.status"],"limits":["ledger provenance is aggregated; raw contribution and verifier audit rows are not expanded","entity matching uses settlement bridge refs and edge commands"]},"papers":[{"corpus_id":38529115,"title":"Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins","citation_count":14,"url":"https://sah.borca.ai/papers/38529115"}],"claims":[{"public_id":"cl_674e309e6545dd1c9d80fe6a19aa39cf","text":"The complex structures of the KIF21A peptide bound to the KANK1 ankyrin domain and to the KANK2 ankyrin domain have been solved.","corpus_id":38529115,"url":"https://sah.borca.ai/claims/cl_674e309e6545dd1c9d80fe6a19aa39cf"},{"public_id":"cl_88d27b820c1d67b0eb5f6593ad540c71","text":"In each complex, KIF21A is recognized by two distinct pockets of the ankyrin domain and adopts a helical conformation upon binding.","corpus_id":38529115,"url":"https://sah.borca.ai/claims/cl_88d27b820c1d67b0eb5f6593ad540c71"},{"public_id":"cl_a105ea31e0b8cf5d3f3f5555d697c69e","text":"A stretch of approximately 22 amino acids in KIF21A is sufficient for binding to KANK1 and its close homolog KANK2.","corpus_id":38529115,"url":"https://sah.borca.ai/claims/cl_a105ea31e0b8cf5d3f3f5555d697c69e"}],"related_concepts":[],"resolved_url":"https://sah.borca.ai/concepts/co_324b74d480a75e01b4d91b39c67ec5f6","url":"https://sah.borca.ai/concepts/co_324b74d480a75e01b4d91b39c67ec5f6"}