Tianxiang Hu

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Publication record
35 papers · 358 citations · H-index 12

PAPERS

Abstract 3961: CBFβ-SMMHC directly activates immune regulatory genes to establish a global immune suppression in mouse AML model
20250 citationsauthor #8
Genomic Analysis Defines Increased Circulating, Leukemia-Induced Macrophages That Promote Immune Suppression in Mouse Models of FGFR1-Driven Leukemogenesis
20250 citationsauthor #14
Metabolic landscape and rewiring in normal hematopoiesis, leukemia and aging.
20253 citationsauthor #6
Abstract 6044: T cell-mediated clearance of BCRABL+ leukemia cells in transgenic mice model of chronic myeloid leukemia
20250 citationsauthor #6
Abstract 187: Macrophage instead of leukemia cell expressed PD-L1 drives T cell exhaustion and immune evasion of BCRABL1 chronic myeloid leukemia
20240 citationsauthor #8
Single-cell analysis defines highly specific leukemia-induced neutrophils and links MMP8 expression to recruitment of tumor associated neutrophils during FGFR1 driven leukemogenesis
202418 citationsauthor #1
A probiotic Limosilactobacillus fermentum GR-3 mitigates colitis-associated tumorigenesis in mice via modulating gut microbiome
202419 citationsauthor #4
Leukemia Associated Macrophages and Neutrophils Contribute to Immune Suppression through PD-L1 and Arginase in BCR-ABL1 Chronic Myeloid Leukemia
20242 citationsauthor #5
Genomic Analysis Defines Increased Circulating, Monocyte-Derived Macrophages That Promote Immune Suppression in Mouse Models of FGFR1-Driven Leukemogenesis and Defines a Multigene Signature That Predicts AML Outcomes
20240 citationsauthor #7
Abstract 1353: CD71 and CD117 identifies an early cancer associated macrophage progenitor population in leukemic mouse bone marrow
20230 citationsauthor #7
Abstract 657: IRAK1 regulated inflammatory signal from the leukemia cells modulates tumor microenvironment and promote leukemogenesis
20230 citationsauthor #7
RHOA-regulated IGFBP2 promotes invasion and drives progression of BCR-ABL1 chronic myeloid leukemia
20226 citationsauthor #12
A truncated derivative of FGFR1 kinase cooperates with FLT3 and KIT to transform hematopoietic stem cells in syndromic and de novo AML
20226 citationsauthor #10
A truncated derivative of FGFR1 kinase cooperates with FLT3 and KIT to transform hematopoietic stem cells in syndromic and de novo AML
20220 citationsauthor #10
AML-060 A Truncated Nucleus Isoform of FGFR1 Drives the Transformation of Leukemia Stem Cells in Leukemogenesis.
20220 citationsauthor #9
Abstract 5837: A truncated nucleus-located derivative of FGFR1 contributes to the transformation of leukemia stem cell in leukemogenesis driven by FGFR1 fusion kinases
20220 citationsauthor #9
IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies
202130 citationsauthor #10
MPN-053: Tumor-Intrinsic IRAKI-Dependent Inflammation Signaling Induces MDSC to Establish Immune Evasion in FGFRI-Driven Hematological Malignancies
20210 citationsauthor #6
Mechanisms of resistance to FGFR1 inhibitors in FGFR1-driven leukemias and lymphomas: implications for optimized treatment
20215 citationsauthor #2
Critical individual roles of the BCR and FGFR1 kinase domains in BCR‐FGFR1‐driven stem cell leukemia/lymphoma syndrome
202012 citationsauthor #9
Rac1/2 activation promotes FGFR1 driven leukemogenesis in stem cell leukemia/lymphoma syndrome
20208 citationsauthor #1
Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome
202010 citationsauthor #10
Distinct signaling programs associated with progression of FGFR1 driven leukemia in a mouse model of stem cell leukemia lymphoma syndrome.
20198 citationsauthor #3
Salubrinal, a novel inhibitor of eIF‐2α dephosphorylation, promotes erythropoiesis at early stage targeted by ufmylation pathway
20198 citationsauthor #5
DNA methyltransferase 1–mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1–driven leukemogenesis
201916 citationsauthor #1
The Gef Domain of the BCR-FGFR1 Chimeric Kinase Attenuates SCLL Progression through the RhoA/Rock/Pten Signaling Axis
20180 citationsauthor #1
Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice.
201811 citationsauthor #1
miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the BCL2L11 and BAX Proapoptotic Genes.
201830 citationsauthor #1
FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome
201822 citationsauthor #1
Hydroxyurea differentially modulates activator and repressors of γ-globin gene in erythroblasts of responsive and non-responsive patients with sickle cell disease in correlation with Index of Hydroxyurea Responsiveness
201718 citationsauthor #2
Hypermethylated LTR retrotransposon exhibits enhancer activity
201718 citationsauthor #1
Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1‐driven leukemia/lymphomas
201749 citationsauthor #3
The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase
201716 citationsauthor #1
Long non-coding RNAs transcribed by ERV-9 LTR retrotransposon act in cis to modulate long-range LTR enhancer function
201744 citationsauthor #1
Non-Coding RNAs Transcribed from ERV-9 LTR Retrotransposons Regulate Erythropoiesis
20141 citationsauthor #1

TIMELINE

2014 1 citations

2017 145 citations

2018 63 citations

2019 32 citations

2020 30 citations

2021 35 citations

2022 12 citations

2023 0 citations

2024 39 citations

2025 3 citations

COAUTHOR MAP

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