Doo Yeon Kim

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Aliases
Doo Y Kim, Doo Y. Kim
Publication record
63 papers · 5,684 citations · H-index 32

PAPERS

Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model
2023128 citationsauthor #12
Evaluation of bumetanide as a potential therapeutic agent for Alzheimer’s disease
202316 citationsauthor #10
The Impact of the Cellular Environment and Aging on Modeling Alzheimer's Disease in 3D Cell Culture Models
202321 citationsauthor #7
Systems analysis of Alzheimer’s disease pathway dysregulation in human subjects is recapitulated in 3d cellular models to reveal P38 MAPK as a therapeutic target that mitigates tau pathology
20230 citationsauthor #13
Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer’s Disease
202229 citationsauthor #4
3D Alzheimer's disease in a dish: Implications for drug discovery
20213 citationsauthor #5
Patterning of interconnected human brain spheroids.
20217 citationsauthor #4
Dissecting Alzheimer's disease pathogenesis in human 2D and 3D models.
202042 citationsauthor #7
Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease
2020124 citationsauthor #16
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via excessive H2O2-production
201911 citationsauthor #17
Rapid removal of amyloid-β aggregates using superparamagnetic nanoparticles
20190 citationsauthor #10
Blood–Brain Barrier Dysfunction in a 3D In Vitro Model of Alzheimer's Disease
2019220 citationsauthor #7
A novel lysosome‐to‐mitochondria signaling pathway disrupted by amyloid‐β oligomers
201860 citationsauthor #10
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
2018684 citationsauthor #16
Hydrogel-incorporating unit in a well: 3D cell culture for high-throughput analysis.
201823 citationsauthor #7
β-Secretase BACE1 Promotes Surface Expression and Function of Kv3.4 at Hippocampal Mossy Fiber Synapses
201817 citationsauthor #10
A 3D Human Tri-Culture System Modeling Neurodegeneration and Neuroinflammation in Alzheimer’s Disease
2018448 citationsauthor #6
Nutrient-induced Mitochondrial Activation (NiMA): A Novel Lysosome-to-Mitochondria Signaling Pathway Disrupted by Amyloid-β Oligomers
20181 citationsauthor #9
BACE1 Regulates Proliferation and Neuronal Differentiation of Newborn Cells in the Adult Hippocampus in Mice
201825 citationsauthor #10
Human Neurospheroid Arrays for In Vitro Studies of Alzheimer’s Disease
2018100 citationsauthor #4
Three‐Dimensional Models of the Human Brain Development and Diseases
201890 citationsauthor #3
Microglial dysfunction as a key pathological change in adrenomyeloneuropathy
201749 citationsauthor #7
Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606
201741 citationsauthor #16
Three-Dimensional Cultures of Human Neural Stem Cells: An Application for Modeling Alzheimer’s Disease Pathogenesis
20170 citationsauthor #8
Supplementary Material for: The E280A Presenilin Mutation Reduces Voltage-Gated Sodium Channel Levels in Neuronal Cells
20170 citationsauthor #1
3D culture models of Alzheimer’s disease: a road map to a “cure-in-a-dish”
20160 citationsauthor #5
3D culture models of Alzheimer’s disease: a road map to a “cure-in-a-dish”
2016114 citationsauthor #5
A 3D human neural cell culture system for modeling Alzheimer's disease
2015242 citationsauthor #11
Alzheimer's in 3D culture: Challenges and perspectives
201591 citationsauthor #6
BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).
201521 citationsauthor #8
γ‐Secretase modulators reduce endogenous amyloid β42 levels in human neural progenitor cells without altering neuronal differentiation
201512 citationsauthor #5
Recapitulating amyloid β and tau pathology in human neural cell culture models: clinical implications.
201524 citationsauthor #6
BACE1 activity regulates cell surface contactin-2 levels
20141 citationsauthor #5
A three-dimensional human neural cell culture model of Alzheimer’s disease
20141,060 citationsauthor #19
BACE1 activity regulates cell surface contactin-2 levels
201449 citationsauthor #5
The E280A Presenilin Mutation Reduces Voltage-Gated Sodium Channel Levels in Neuronal Cells
20135 citationsauthor #1
BACE1 and presenilin/γ‐secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage‐gated potassium channels
201345 citationsauthor #7
Surface trafficking of sodium channels in cells and in hippocampal slices.
20118 citationsauthor #1
Alzheimer's secretases regulate voltage-gated sodium channels.
201027 citationsauthor #3
Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit
201037 citationsauthor #2
Reduced Sodium Channel Nav1.1 Levels in BACE1-null Mice*
201085 citationsauthor #1
Familial Alzheimer's disease mutations in presenilin 1 do not alter levels of the secreted amyloid-beta protein precursor generated by beta-secretase cleavage.
200920 citationsauthor #3
HtrA2 Regulates β-Amyloid Precursor Protein (APP) Metabolism through Endoplasmic Reticulum-associated Degradation*
200770 citationsauthor #6
BACE1 regulates voltage-gated sodium channels and neuronal activity
2007319 citationsauthor #1
Presenilin/γ-Secretase-mediated Cleavage Regulates Association of Leukocyte-Common Antigen-related (LAR) Receptor Tyrosine Phosphatase with β-Catenin*
200753 citationsauthor #2
Presenilin/gamma-secretase and alpha-secretase-like peptidases cleave human MHC Class I proteins.
200718 citationsauthor #2
Presenilin/gamma-secretase-mediated cleavage regulates association of leukocyte-common antigen-related (LAR) receptor tyrosine phosphatase with beta-catenin.
200728 citationsauthor #2
HtrA2Regulates-AmyloidPrecursorProtein(APP)Metabolism throughEndoplasmicReticulum-associatedDegradation *□
20070 citationsauthor #5
Presenilin/γ-secretase and α-secretase-like peptidases cleave human MHC Class I proteins
200740 citationsauthor #2
Neuronal nitric oxide synthase (nNOS) modulates the JNK1 activity through redox mechanism: a cGMP independent pathway.
200613 citationsauthor #4
Presenilin/γ‐secretase activity regulates protein clearance from the endocytic recycling compartment
200663 citationsauthor #3
Presenilin/γ-Secretase-mediated Cleavage of the Voltage-gated Sodium Channel β2-Subunit Regulates Cell Adhesion and Migration*
2005133 citationsauthor #1
Presenilin/-Secretase-mediated Cleavage of the Voltage-gated Sodium Channel 2-Subunit Regulates Cell Adhesion
20050 citationsauthor #1
Caspase-3-mediated cleavage of PHF-1 tau during apoptosis irrespective of excitotoxicity and oxidative stress: an implication to Alzheimer's disease.
200526 citationsauthor #4
Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration.
200580 citationsauthor #1
The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease.
2004267 citationsauthor #5
P4-290 Voltage-gated sodium channel beta2 subunit is processed by alpha-, beta- and gamma-secretases, generating fragments elevated in AD brains
20040 citationsauthor #1
Analysis of mitochondrial free radical generation in animal models of neuronal disease.
200235 citationsauthor #1
Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage.
200263 citationsauthor #1
Cellular and molecular pathways of ischemic neuronal death.
2002290 citationsauthor #2
Nectin-1α, an Immunoglobulin-like Receptor Involved in the Formation of Synapses, Is a Substrate for Presenilin/γ-Secretase-like Cleavage*
2002154 citationsauthor #1
Excitotoxicity, Oxidative Stress, and Apoptosis in Ischemic Neuronal Death
200116 citationsauthor #2
High abundance of GluR1 mRNA and reduced Q/R editing of GluR2 mRNA in individual NADPH-diaphorase neurons.
200143 citationsauthor #1

TIMELINE

2001 59 citations

2002 542 citations

2004 267 citations

2005 239 citations

2006 76 citations

2007 528 citations

2009 20 citations

2010 149 citations

2011 8 citations

2013 50 citations

2014 1,110 citations

2015 390 citations

2016 114 citations

2017 90 citations

2018 1,448 citations

2019 231 citations

2020 166 citations

2021 10 citations

2022 29 citations

2023 165 citations

COAUTHOR MAP

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