S. Varadharajan

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S Varadharajan, S. Varadharajan, Srinidhi Varadharajan
Publication record
46 papers · 755 citations · H-index 14

PAPERS

EXTH-101. CAR T-cells targeted to B7-H3 are effective against ependymomas but show limited response in the immune competent setting
20250 citationsauthor #4
EXTH-74. Nuclear Transport as a Therapeutic Vulnerability in ZFTA-RELA Ependymoma
20250 citationsauthor #3
EPCO-12. DOMINANT MALIGNANT LINEAGE LEVERAGE RESTRICTED EPIGENOMIC PROGRAMS TO DRIVE EPENDYMOMA DEVELOPMENT
20250 citationsauthor #8
Abstract LB105: Integrated molecular profiling of pediatric brain tumors: Insights into subtypes and biomarker discovery
20250 citationsauthor #5
Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis
20251 citationsauthor #3
B7-H3 CAR T Cells Are Effective against Ependymomas but Limited by Tumor Size and Immune Response
20253 citationsauthor #3
TMOD-14. Synthetic ZFTA-fusions pinpoint IDR acquisition as a mechanism of brain tumor development
20250 citationsauthor #3
EPEN-22. ZFTA FUSION ONCOPROTEINS DRIVE ONCOGENESIS THROUGH ASSEMBLY OF BIOMOLECULAR CONDENSATES
20240 citationsauthor #1
TMET-39. DUAL TARGETING OF MAP KINASE SIGNALING AND METABOLISM IS A THERAPEUTIC VULNERABILITY IN PEDIATRIC DIFFUSE MIDLINE GLIOMAS
20240 citationsauthor #4
296 CAR T-cells targeted to B7-H3 are effective against ependymomas but show limited response in the immune competent setting
20240 citationsauthor #2
Histone serotonylation regulates ependymoma tumorigenesis
202432 citationsauthor #5
Integrated transcriptomic landscape of medulloblastoma and ependymoma reveals novel tumor subtype-specific biology
20241 citationsauthor #6
Dominant Malignant Clones Leverage Lineage Restricted Epigenomic Programs to Drive Ependymoma Development
20240 citationsauthor #7
EPEN-30. PROTON THERAPY FOR PEDIATRIC INTRACRANIAL EPENDYMOMA: A SYSTEMATIC REVIEW, META-ANALYSIS AND META-REGRESSION
20240 citationsauthor #6
TULIPs decorate the three-dimensional genome of PFA ependymoma.
202417 citationsauthor #18
EPEN-04. OVERWHELMING ZFTA-RELA NUCLEAR LOCALIZATION AS A THERAPEUTIC STRATEGY AGAINST EPENDYMOMA
20240 citationsauthor #5
EPEN-05. TRANSCRIPTIONAL FACTOR-DIRECTED EPIGENETIC REGULATION IN CANCER NEUROSCIENCE OF ZFTA-RELA EPENDYMOMA
20230 citationsauthor #3
EPEN-01. ZFTA-RELA FUSION PROGRAMS CONVERGE ON YAP PATHWAY ACTIVATION IN EPENDYMOMA
20230 citationsauthor #2
DIPG-36. H3K27M HISTONE MUTANT GLIOMAS ARE SENSITIVE TO METHIONINE LOSS AND MAT2A INHIBITION THROUGH A NOVEL FEEDBACK MECHANISM BETWEEN AMD1 AND METTL16
20230 citationsauthor #4
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
202313 citationsauthor #4
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome
202248 citationsauthor #4
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas
202277 citationsauthor #5
TMET-09. LOSS OF MAT2A COMPROMISES METHIONINE METABOLISM AND REPRESENTS A VULNERABILITY IN H3K27M MUTANT GLIOMAS
20220 citationsauthor #4
Sox9 directs divergent epigenomic states in brain tumor subtypes
202215 citationsauthor #4
Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome
20222 citationsauthor #4
EPCO-38. TYPE B ULTRA LONG-RANGE INTERACTIONS IN PFAS (TULIPS) ARE RECURRENT EPIGENOMIC FEATURES OF PFA EPENDYMOMA
20220 citationsauthor #17
Author Correction: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
20213 citationsauthor #24
ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors.
202141 citationsauthor #13
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma.
202162 citationsauthor #3
EPEN-01. C11ORF95-RELA DICTATES ONCOGENIC TRANSCRIPTIONAL PROGRAMS TO DRIVE AGGRESSIVE SUPRATENTORIAL EPENDYMOMA
20211 citationsauthor #3
EPEN-30. C11ORF95-RELA FUSION PROTEIN ENGAGES NOVEL GENOMIC LOCI TO DRIVE MURINE EPENDYMOMA GROWTH
20200 citationsauthor #3
Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
2020183 citationsauthor #24
A High-Quality Assembly of the Nine-Spined Stickleback (Pungitius pungitius) Genome
201974 citationsauthor #1
Comparative genomics in teleost fish: Insights into forces driving genome evolution
20190 citationsauthor #1
Metagenomic Shotgun Analyses Reveal Complex Patterns of Intra- and Interspecific Variation in the Intestinal Microbiomes of Codfishes
201932 citationsauthor #3
Switching on the light: using metagenomic shotgun sequencing to characterize the intestinal microbiome of Atlantic cod
201931 citationsauthor #3
The assembly and annotation of stickleback
20190 citationsauthor #1
Genome sequencing of the nine-spined stickleback (Pungitius pungitius) provides insights into chromosome evolution
20195 citationsauthor #1
The Chromosome-Level Genome Assembly of European Grayling Reveals Aspects of a Unique Genome Evolution Process Within Salmonids
201930 citationsauthor #3
Grayling draft genome assembly and analysis
20170 citationsauthor #1
The Grayling Genome Reveals Selection on Gene Expression Regulation after Whole-Genome Duplication
201743 citationsauthor #1
Exploring in silico prediction of the unbound brain-to-plasma drug concentration ratio: model validation, renewal, and interpretation.
201540 citationsauthor #1
Building predictive unbound brain-to-plasma concentration ratio (Kp,uu,brain) models
20140 citationsauthor #1
Potential role of cation-aquaporin interactions in autism
20093 citationsauthor #2
Dual Sites For Heme Biosynthesis In The Malarial Parasite
20040 citationsauthor #1
Title: Transcriptomic landscape identifies two unrecognized ependymoma subtypes and novel pathways in medulloblastoma
year unknown0 citationsauthor #6

TIMELINE

2004 0 citations

2009 3 citations

2014 0 citations

2015 40 citations

2017 43 citations

2019 172 citations

2020 183 citations

2021 107 citations

2022 142 citations

2023 13 citations

2024 50 citations

2025 4 citations

Unknown 0 citations

S. Varadharajan

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