D. Boyd

PROFILE

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Aliases
Douglas D Boyd, Douglas Boyd, Douglas David Boyd, D Boyd, Douglas D. Boyd, D D Boyd, D. Boyd
Publication record
95 papers · 7,244 citations · H-index 47

PAPERS

ZKSCAN3 is a master transcriptional repressor of autophagy.
2013256 citationsauthor #7
Accelerated urokinase-receptor protein turnover triggered by interference with the addition of the glycolipid anchor.
20112 citationsauthor #5
Regulation of u-PAR gene expression by H2A.Z is modulated by the MEK–ERK/AP-1 pathway
201122 citationsauthor #2
MDM 2 MEDIATES UBIQUITINATION AND DEGRADATION OF ACTIVATING TRANSCRITION FACTOR 3
20104 citationsauthor #4
MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3*
201052 citationsauthor #4
The previously undescribed ZKSCAN3 (ZNF306) is a novel "driver" of colorectal cancer progression.
200878 citationsauthor #8
Unbiased Screening for Transcriptional Targets of ZKSCAN3 Identifies Integrin β4 and Vascular Endothelial Growth Factor as Downstream Targets*
200852 citationsauthor #4
A Novel High-Throughput Screening System Identifies a Small Molecule Repressive for Matrix Metalloproteinase-9 Expression
200821 citationsauthor #7
A novel function of caspase‐8 in the regulation of androgen‐receptor‐driven gene expression
200717 citationsauthor #4
Regulation of matrix metalloproteinase gene expression
2007782 citationsauthor #2
Identification of an histone H3 acetylated/K4-methylated-bound intragenic enhancer regulatory for urokinase receptor expression
200711 citationsauthor #5
Characterization of the Retino! and Retinoic Acid Binding Proteins in the Human Prostate1
20060 citationsauthor #1
Plasticity in urokinase-type plasminogen activator receptor (uPAR) display in colon cancer yields metastable subpopulations oscillating in cell surface uPAR density--implications in tumor progression.
200613 citationsauthor #8
P4. Tumor suppressor Pdcd4 inhibits invasion and regulates urokinase-receptor (u-PAR) gene expression via Sp-transcription factors
20060 citationsauthor #4
ATF3 Regulates the Stability of p53: A Link to Cancer
200684 citationsauthor #2
ZNF306, a novel zinc finger transcription factor, drives colon cancer progression – An alternate genetic pathway in tumor progression?
20060 citationsauthor #6
Expression Cloning Identifies Transgelin (SM22) as a Novel Repressor of 92-kDa Type IV Collagenase (MMP-9) Expression*
2006121 citationsauthor #3
Histone H3 Acetylation and H3 K4 Methylation Define Distinct Chromatin Regions Permissive for Transgene Expression
2006180 citationsauthor #2
Role of plasminogen activator and of 92-KDa type IV collagenase in glioblastoma invasion using anin vitro Matrigel model
200547 citationsauthor #4
Expression cloning of novel regulators of 92 kDa type IV collagenase expression.
200514 citationsauthor #2
Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination
2005222 citationsauthor #4
Activating transcription factor 3 (ATF3) stabilizes p53 in genotoxic response
20051 citationsauthor #3
Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter.
200522 citationsauthor #2
Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin.
2005123 citationsauthor #5
Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.
2005148 citationsauthor #11
A bisanthracycline (WP631) represses uPAR gene expression and cell migration of RKO colon cancer cells by interfering with transcription factor binding to a chromatin-accessible -148/-124 promoter region.
200513 citationsauthor #6
Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor.
200492 citationsauthor #4
The Kruppel-like KLF4 Transcription Factor, a Novel Regulator of Urokinase Receptor Expression, Drives Synthesis of This Binding Site in Colonic Crypt Luminal Surface Epithelial Cells*
200443 citationsauthor #4
Involvement of heparanase in tumor metastases: a new target in cancer therapy?
200419 citationsauthor #1
Genetic Deletion of Glycogen Synthase Kinase-3β Abrogates Activation of IκBα Kinase, JNK, Akt, and p44/p42 MAPK but Potentiates Apoptosis Induced by Tumor Necrosis Factor*
2004176 citationsauthor #4
A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NFκB motif drives the transition from a repressed to an activated state of gene expression
200450 citationsauthor #4
Combination of an Src Kinase Inhibitor with a Novel Pharmacological Antagonist of the Urokinase Receptor Diminishes in Vitro Colon Cancer Invasiveness
200441 citationsauthor #1
Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme
200442 citationsauthor #6
Repression of 92-kDa Type IV Collagenase Expression by MTA1 Is Mediated through Direct Interactions with the Promoter via a Mechanism, Which Is Both Dependent on and Independent of Histone Deacetylation*
200371 citationsauthor #4
Transgenic mice demonstrate novel promoter regions for tissue-specific expression of the urokinase receptor gene.
200312 citationsauthor #7
A urokinase-derived peptide (A6) increases survival of mice bearing orthotopically grown prostate cancer and reduces lymph node metastasis.
200340 citationsauthor #1
Tumor-specific transcription factor binding to an activator protein-2/Sp1 element of the urokinase-type plasminogen activator receptor promoter in a first large series of resected gastrointestinal cancers.
200326 citationsauthor #3
Biochi ~ ic ~ a et Biophysica A ~ ta Stimulation of urokinase expression by TNF-a requires the activation of binding sites for the AP-1 and PEA 3 transcription factors
20030 citationsauthor #3
Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro
200296 citationsauthor #4
ATF3 Represses 72-kDa Type IV Collagenase (MMP-2) Expression by Antagonizing p53-dependent trans-Activation of the Collagenase Promoter*
200297 citationsauthor #3
Interferons Inhibit Tumor Necrosis Factor-α-mediated Matrix Metalloproteinase-9 Activation via Interferon Regulatory Factor-1 Binding Competition with NF-κB*
2002101 citationsauthor #2
An inhibitor of c-jun aminoterminal kinase (SP600125) represses c-Jun activation, DNA-binding and PMA-inducible 92-kDa type IV collagenase expression.
2002143 citationsauthor #3
Transcriptional Control of Proteases
20021 citationsauthor #3
Interferons inhibit tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 activation via interferon regulatory factor-1 binding competition with NF-kappa B.
200247 citationsauthor #2
Activation of Src kinase in primary colorectal carcinoma
2002264 citationsauthor #2
KiSS-1 represses 92-kDa type IV collagenase expression by down-regulating NF-kappa B binding to the promoter as a consequence of Ikappa Balpha -induced block of p65/p50 nuclear translocation.
200178 citationsauthor #3
Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines.
200126 citationsauthor #4
KiSS-1 Represses 92-kDa Type IV Collagenase Expression by Down-regulating NF-κB Binding to the Promoter as a Consequence of IκBα-induced Block of p65/p50 Nuclear Translocation*
2001196 citationsauthor #3
Regulation of the uPA gene in various grades of human glioma cells.
200121 citationsauthor #4
First clinical evidence of a combined AP-2/Sp1 promoter motif as a tumor-specific activator of urokinase-receptor (u-PAR) expression in resected gastrointestinal cancers
20011 citationsauthor #3
Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor.
200074 citationsauthor #7
Transcriptional Induction of the Urokinase Receptor Gene by a Constitutively Active Src
199973 citationsauthor #8
PD 098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma
199958 citationsauthor #8
MMP-9 expression and predicting the invasive characteristics of HNSCC
19990 citationsauthor #5
Transactivation of the Urokinase-type Plasminogen Activator Receptor Gene through a Novel Promoter Motif Bound with an Activator Protein-2α-related Factor*
199945 citationsauthor #7
Measurement of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Blood and Tissues: Clinical and Experimental Applications
1999249 citationsauthor #7
Targeted disruption of the K-Ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis
199959 citationsauthor #5
Constitutive p38 activity: A new mechanism of HNSCC invasion
19990 citationsauthor #2
Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway
1999282 citationsauthor #6
Cancer cell heparanase activity associated with invasion and metastasis.
199818 citationsauthor #4
CANCER C ELL H EPARANASE ACTIVITY A SSOCIATED W ITH INVASION A ND METASTASIS
19980 citationsauthor #4
An orthotopic floor‐of‐mouth cancer model allows quantification of tumor invasion
199840 citationsauthor #3
Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion.
1998248 citationsauthor #3
Stimulation of urokinase-type plasminogen activator receptor expression by PMA requires JNK1-dependent and -independent signaling modules
199852 citationsauthor #6
Organ-site dependence for the production of urokinase-type plasminogen activator and metastasis by human renal cell carcinoma cells.
199730 citationsauthor #3
In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor
1997110 citationsauthor #6
Regulation of 92 kDa type IV collagenase expression by the jun aminoterminal kinase- and the extracellular signal-regulated kinase-dependent signaling cascades
1997247 citationsauthor #5
Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade
199772 citationsauthor #6
Requirement of an Upstream AP-1 Motif for the Constitutive and Phorbol Ester-inducible Expression of the Urokinase-type Plasminogen Activator Receptor Gene*
199684 citationsauthor #8
Invasion and metastasis
1996221 citationsauthor #1
Breast Cancer Metastasis: Prognosis and Monitoring of Metastatic Disease.
19960 citationsauthor #1
Regulation of urokinase‐type plasminogen activator expression by an ERK1‐dependent signaling pathway in a squamous cell carcinoma cell line
199654 citationsauthor #6
Effect of PD 098059, a specific inhibitor of mitogen-activated protein kinase kinase, on urokinase expression and in vitro invasion.
199659 citationsauthor #4
Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites Including Closely Spaced PEA3/ets and AP-1 Sequences (*)
1996374 citationsauthor #7
Up-regulation of urokinase-type plasminogen activator expression by the HER2/neu proto-oncogene.
199528 citationsauthor #7
Modulation of urokinase-type plasminogen-activator expression by the wild-type and mutated p53 tumor-suppressor gene.
19952 citationsauthor #2
Involvement of a Mitogen-activated Protein Kinase Signaling Pathway in the Regulation of Urokinase Promoter Activity by c-Ha-ras(*)
199577 citationsauthor #4
Mechanisms of invasion by head and neck cancers.
19955 citationsauthor #1
Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.
199519 citationsauthor #7
Stimulation of urokinase expression by TNF-alpha requires the activation of binding sites for the AP-1 and PEA3 transcription factors.
199527 citationsauthor #3
Transcriptional activation of the urokinase receptor gene in invasive colon cancer
199444 citationsauthor #4
Divergent effect of n,n-dimethylformamide on the expression of urokinase and its receptor
19930 citationsauthor #6
Regulation of urokinase‐type plasminogen activator expression in squamous‐cell carcinoma of the oral cavity
199354 citationsauthor #3
Role and regulation of expression of 92‐kDa type‐IV collagenase (MMP‐9) in 2 invasive squamous‐cell‐carcinoma cell lines of the oral cavity
1993136 citationsauthor #7
Expression of Urokinase and Its Receptor in Invasive and Non-Invasive Prostate Cancer Cell Lines
199259 citationsauthor #8
Regulation of the Urokinase Receptor by Its Plasminogen Activator
199111 citationsauthor #2
Involvement of urokinase and its receptor in the invasiveness of human prostatic carcinoma cell lines.
1991123 citationsauthor #2
Urokinase-Dependent Proteolysis in Cultured Colon Cancer Is Directed by Its Receptor
199111 citationsauthor #2
Insensitivity of laminin degradation directed by receptor bound urokinase to PAI-1 in cultured colon cancer.
199031 citationsauthor #2
Examination of the role of the urokinase receptor in human colon cancer mediated laminin degradation.
1989105 citationsauthor #4
Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation.
198872 citationsauthor #4
A comparison of retinol binding in human hyperplastic and malignant prostate.
19854 citationsauthor #1
Is the human hyperplastic and malignant prostate a target for retinoids
19850 citationsauthor #1
Nuclear retinoic acid binding protein in human prostate adenomas.
19858 citationsauthor #1
Characterization of the retinol and retinoic acid binding proteins in the human prostate.
198414 citationsauthor #1

TIMELINE

1984 14 citations

1985 12 citations

1988 72 citations

1989 105 citations

1990 31 citations

1991 145 citations

1992 59 citations

1993 190 citations

1994 44 citations

1995 158 citations

1996 792 citations

1997 459 citations

1998 358 citations

1999 766 citations

2000 74 citations

2001 322 citations

2002 749 citations

2003 149 citations

2004 463 citations

2005 590 citations

2006 398 citations

2007 810 citations

2008 151 citations

2010 56 citations

2011 24 citations

2013 256 citations

D. Boyd

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