M. G. Pedersen

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Aliases
M G Pedersen, Morten G Pedersen, Morten G. Pedersen, Morten Gram Pedersen
Publication record
80 papers · 1,992 citations · H-index 26

PAPERS

Human pancreatic islet miRNA-mRNA networks of altered miRNAs due to glycemic status
20229 citationsauthor #3
Machine learning provides insight into models of heterogeneous electrical activity in human beta-cells.
20225 citationsauthor #2
Mixed-Mode Oscillations in Coupled FitzHugh-Nagumo Oscillators: Blow-Up Analysis of Cusped Singularities
20229 citationsauthor #2
Amplitude-modulated spiking as a novel route to bursting: Coupling-induced mixed-mode oscillations by symmetry breaking.
202224 citationsauthor #1
Geometric analysis of mixed-mode oscillations in a model of electrical activity in human beta-cells
20211 citationsauthor #2
Modeling Pharmacokinetics of Doxorubicin in Multiple Myeloma Cells
20211 citationsauthor #4
Geometric analysis of mixed-mode oscillations in a model of electrical activity in human beta-cells
202122 citationsauthor #2
Calcium Signaling in the Photodamaged Skin: In Vivo Experiments and Mathematical Modeling
202114 citationsauthor #8
Recent advances in mathematical modeling and statistical analysis of exocytosis in endocrine cells.
202012 citationsauthor #1
Insulin release in health and disease
20200 citationsauthor #2
Heterogeneous alpha-cell population modeling of glucose-induced inhibition of electrical activity.
202011 citationsauthor #3
Stopping waves: geometric analysis of coupled bursters in an asymmetric excitation field
20190 citationsauthor #2
Stopping waves: geometric analysis of coupled bursters in an asymmetric excitation field
20195 citationsauthor #2
From Local to Global Modeling for Characterizing Calcium Dynamics and Their Effects on Electrical Activity and Exocytosis in Excitable Cells
20193 citationsauthor #2
Calcium signaling and secretory granule pool dynamics underlie biphasic insulin secretion and its amplification by glucose: experiments and modeling.
201936 citationsauthor #1
Gap-junction coupling can prolong beta-cell burst period by an order of magnitude via phantom bursting.
201817 citationsauthor #2
Explicit Theoretical Analysis of How the Rate of Exocytosis Depends on Local Control by Ca2+ Channels
201812 citationsauthor #2
Hopf bifurcation analysis of the fast subsystem of a polynomial phantom burster model
20182 citationsauthor #2
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
20170 citationsauthor #2
CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
201772 citationsauthor #2
Gap-junction coupling and ATP-sensitive potassium channels in human β-cell clusters: Effects on emergent dynamics.
201711 citationsauthor #2
Ca2+ channel clustering with insulin-containing granules is disturbed in type 2 diabetes
201775 citationsauthor #10
Spatiotemporal Modeling of Triggering and Amplifying Pathways in GLP-1 Secreting Intestinal L Cells.
201710 citationsauthor #2
Concise Whole-Cell Modeling of BKCa-CaV Activity Controlled by Local Coupling and Stoichiometry.
201716 citationsauthor #4
Biological mechanisms beyond network analysis via mathematical modeling: Comment on "Network science of biological systems at different scales: A review" by Marko Gosak et al.
20171 citationsauthor #1
Statistical Frailty Modeling for Quantitative Analysis of Exocytotic Events Recorded by Live Cell Imaging: Rapid Release of Insulin-Containing Granules Is Impaired in Human Diabetic β-cells
20163 citationsauthor #4
Mathematical Modeling of Human Pancreatic Alpha-Cells: Insight into the Role of SGLT2 in Glucagon Secretion
20160 citationsauthor #1
Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells
201660 citationsauthor #1
Is Bursting More Effective than Spiking in Evoking Pituitary Hormone Secretion? A Spatiotemporal Simulation Study of Calcium Diffusion and Exocytosis
20160 citationsauthor #4
Heterogeneity and nearest-neighbor coupling can explain small-worldness and wave properties in pancreatic islets.
201636 citationsauthor #2
Is bursting more effective than spiking in evoking pituitary hormone secretion? A spatiotemporal simulation study of calcium and granule dynamics.
201633 citationsauthor #4
Mathematical modelling of local calcium and regulated exocytosis during inhibition and stimulation of glucagon secretion from pancreatic alpha‐cells
201527 citationsauthor #2
New trends and perspectives in nonlinear intracellular dynamics: one century from Michaelis–Menten paper
201551 citationsauthor #4
Reactive oxygen and nitrogen species disturb Ca2+ oscillations in insulin-secreting MIN6 β-cells
20153 citationsauthor #3
Mathematical modeling of gap junction coupling and electrical activity in human β-cells
201540 citationsauthor #4
Inwardly rectifying Kir2.1 currents in human β-cells control electrical activity: characterisation and mathematical modelling.
201516 citationsauthor #4
Mathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 Secretion
20159 citationsauthor #2
Minimal modeling of insulin secretion in the perfused rat pancreas: a drug effect case study.
20149 citationsauthor #2
Modeling Electrical Activity in Intestinal L-Cells
20140 citationsauthor #2
Calcium Current Inactivation Rather than Pool Depletion Explains Reduced Exocytotic Rate with Prolonged Stimulation in Insulin-Secreting INS-1 832/13 Cells
20146 citationsauthor #1
Mathematical Modeling of Heterogeneous Electrophysiological Responses in Human β-Cells
201472 citationsauthor #3
Clustering of L-type Ca2+-channels promotes exocytosis of individual secretory granules
20141 citationsauthor #5
15 – Insulin Modelling
20140 citationsauthor #1
Advancing Our Understanding of the Glucose System via Modeling: A Perspective
201440 citationsauthor #3
Complex patterns of metabolic and Ca²⁺ entrainment in pancreatic islets by oscillatory glucose.
201335 citationsauthor #1
Multiscale modelling of insulin secretion during an intravenous glucose tolerance test
201311 citationsauthor #1
Modeling SK-Channels and Electrical Activity in Human Beta-Cells
20130 citationsauthor #4
Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
2012230 citationsauthor #12
Prediabetes: Evaluation of β-Cell Function
201214 citationsauthor #2
Whole-Body and Cellular Models of Glucose-Stimulated Insulin Secretion
20111 citationsauthor #2
Multiscale Modeling of Insulin Secretion
201121 citationsauthor #1
Mathematical modeling and statistical analysis of calcium-regulated insulin granule exocytosis in β-cells from mice and humans.
201130 citationsauthor #1
On depolarization-evoked exocytosis as a function of calcium entry: possibilities and pitfalls.
201112 citationsauthor #1
Glucose-dependent docking and SNARE protein-mediated exocytosis in mouse pancreatic alpha-cell
201141 citationsauthor #2
Insulin Secretory Granules Enter a Highly Calcium‐Sensitive State following Palmitate‐Induced Dissociation from Calcium Channels: A Theoretical Study
20109 citationsauthor #1
Modeling Mechanisms of Cell Secretion
201013 citationsauthor #4
A biophysical model of electrical activity in human β-cells.
201062 citationsauthor #1
Introducing total substrates simplifies theoretical analysis at non-negligible enzyme concentrations: pseudo first-order kinetics and the loss of zero-order ultrasensitivity
201034 citationsauthor #1
Cellular modeling: insight into oral minimal models of insulin secretion.
201040 citationsauthor #1
The effect of noise and coupling on beta cell excitation dynamics
20090 citationsauthor #2
Contributions of Mathematical Modeling of Beta Cells to the Understanding of Beta-Cell Oscillations and Insulin Secretion
200942 citationsauthor #1
Newcomer insulin secretory granules as a highly calcium-sensitive pool
2009100 citationsauthor #1
Stochastic and coherent dynamics of single and coupled beta cells
20080 citationsauthor #2
Quasi steady-state approximations in complex intracellular signal transduction networks – a word of caution
200852 citationsauthor #1
The total quasi-steady-state approximation for complex enzyme reactions
200857 citationsauthor #1
A subcellular model of glucose-stimulated pancreatic insulin secretion
200861 citationsauthor #1
Wave-Block Due to a Threshold Gradient Underlies Limited Coordination in Pancreatic Islets
200812 citationsauthor #1
Mathematical Models of Open and Closed Biochemical Reactions in Living Cells
20070 citationsauthor #2
Interaction of glycolysis and mitochondrial respiration in metabolic oscillations of pancreatic islets.
2007103 citationsauthor #3
The Effect of Noise on beta-Cell Burst Period
200720 citationsauthor #1
Phantom bursting is highly sensitive to noise and unlikely to account for slow bursting in beta-cells: considerations in favor of metabolically driven oscillations.
200726 citationsauthor #1
Dynamics and Synchrony of Pancreatic beta-cells and Islets
20060 citationsauthor #1
Evidence that calcium feedback and glycolytic oscillations are both important in pancreatic beta-cells: A computational and experimental study
20060 citationsauthor #5
Intra- and inter-islet synchronization of metabolically driven insulin secretion.
2005140 citationsauthor #1
Experimental and Theoretical Study of Entrainment of Calcium and Metabolic Oscillations in Pancreatic Islets
20050 citationsauthor #1
Wave speeds of density dependent Nagumo diffusion equations – inspired by oscillating gap-junction conductance in the islets of Langerhans
200516 citationsauthor #1
A mathematical approach to the study of signal transduction pathways in MAPK cascade
20052 citationsauthor #2
Quasi steady-state approximations in signal transduction - a word of caution
20050 citationsauthor #1
A comment on noise enhanced bursting in pancreatic beta-cells.
200518 citationsauthor #1
Homogenization of Heterogeneously Coupled Bistable ODE's—Applied to Excitation Waves in Pancreatic Islets of Langerhans
200414 citationsauthor #1

TIMELINE

2004 14 citations

2005 176 citations

2006 0 citations

2007 149 citations

2008 182 citations

2009 142 citations

2010 158 citations

2011 105 citations

2012 244 citations

2013 46 citations

2014 128 citations

2015 146 citations

2016 132 citations

2017 185 citations

2018 31 citations

2019 44 citations

2020 23 citations

2021 38 citations

2022 47 citations

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