J. Hock

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Aliases
Janet M Hock, J.m. Hock, J.m Hock, J. Hock, J Hock, J. M. Hock, J M Hock, Janet M. Hock, Janet Hock
Publication record
97 papers · 7,540 citations · H-index 40

PAPERS

Editorial: Novel Endocrine Functions of Bone Marrow Fat
20191 citationsauthor #3
Enhanced but hypofunctional osteoclastogenesis in an autosomal dominant osteopetrosis type II case carrying a c.1856C>T mutation in CLCN7
201616 citationsauthor #3
MicroRNA-17-92 cluster regulates pancreatic beta-cell proliferation and adaptation.
201636 citationsauthor #10
Lovastatin enhances adenovirus-mediated TRAIL induced apoptosis by depleting cholesterol of lipid rafts and affecting CAR and death receptor expression of prostate cancer cells
201426 citationsauthor #6
Aberrant overexpression of FOXM1 transcription factor plays a critical role in lung carcinogenesis induced by low doses of arsenic
201424 citationsauthor #2
MiR-335 Inhibits Small Cell Lung Cancer Bone Metastases via IGF-IR and RANKL Pathways
2013102 citationsauthor #7
MicroRNA-204 critically regulates carcinogenesis in malignant peripheral nerve sheath tumors.
201265 citationsauthor #5
A novel animal model for bone metastasis in human lung cancer.
201214 citationsauthor #8
Novel Interactions between FOXM1 and CDC25A Regulate the Cell Cycle
201240 citationsauthor #6
Basic Aspects of PTH in Skeletal Health
20102 citationsauthor #1
Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis type 1
201020 citationsauthor #3
Abnormal osteoblast development from Nf1 null embryonic stem cells
20101 citationsauthor #5
MicroRNA‐10b regulates tumorigenesis in neurofibromatosis type 1
2010104 citationsauthor #13
Proteomic characteristics of ex vivo-enriched adult human bone marrow mononuclear cells in continuous perfusion cultures.
20099 citationsauthor #2
Skeletal abnormalities in neurofibromatosis type 1: Approaches to therapeutic options
2009166 citationsauthor #5
Chapter 81. Osteogenic Osteosarcoma
20090 citationsauthor #1
IGF-I improved bone mineral density and body composition of weaver mutant mice.
200812 citationsauthor #8
RECQL4-deficient cells are hypersensitive to oxidative stress/damage: Insights for osteosarcoma prevalence and heterogeneity in Rothmund-Thomson syndrome.
200677 citationsauthor #4
Recql4 haploinsufficiency in mice leads to defects in osteoblast progenitors: Implications for low bone mass phenotype.
200617 citationsauthor #7
Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.
2006135 citationsauthor #10
Serum proteome profiles identifies parathyroid hormone physiologic response
200615 citationsauthor #8
Hyperactivation of p21ras and PI3-K Cooperate To Alter Murine and Human NF1 Haploinsufficient Osteoclast Functions.
20060 citationsauthor #5
Neurofibromatosis Type 1 Gene Haploinsufficiency Reduces AP-1 Gene Expression without Abrogating the Anabolic Effect of Parathyroid Hormone
200610 citationsauthor #9
IGF-I and postnatal growth of weaver mutant mice
20059 citationsauthor #4
Periosteum: biology, regulation, and response to osteoporosis therapies.
2004424 citationsauthor #2
Nf1 Plays an Essential Role in Osteoclasts Development Via Hyperactivation of Ras- PI3K Signaling.
20040 citationsauthor #4
Anabolic and catabolic bone effects of human parathyroid hormone (1-34) are predicted by duration of hormone exposure.
2003205 citationsauthor #7
Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.
2003185 citationsauthor #17
Bone Mineral and Collagen Quality in Humeri of Ovariectomized Cynomolgus Monkeys Given rhPTH(1–34) for 18 Months
200382 citationsauthor #4
Osteoblast intracellular localization of Nmp4 proteins.
20028 citationsauthor #9
The role of strain in the response of rapidly growing young male rat bones to parathyroid hormone.
20020 citationsauthor #3
Introduction: osteosarcoma session.
20020 citationsauthor #1
Actions of Parathyroid Hormone
200257 citationsauthor #1
Skeletal efficacy with parathyroid hormone in rats was not entirely beneficial with long-term treatment.
200236 citationsauthor #3
Treatment with human parathyroid hormone (1-34) for 18 months increases cancellous bone volume and improves trabecular architecture in ovariectomized cynomolgus monkeys (Macaca fascicularis).
2001149 citationsauthor #4
CHAPTER 11 – Parathyroid Hormone: Anabolic and Catabolic Effects on Bone and Interactions with Growth Factors
20016 citationsauthor #1
Effects of human parathyroid hormone (1-34), LY333334, on bone mass, remodeling, and mechanical properties of cortical bone during the first remodeling cycle in rabbits.
200194 citationsauthor #6
The effects of PTH (1-34) on bone structure and strength in ovariectomized monkeys.
200125 citationsauthor #3
Osteoblast Apoptosis and Bone Turnover
2001228 citationsauthor #1
Cloning and Functional Analysis of a Family of Nuclear Matrix Transcription Factors (NP/NMP4) that Regulate Type I Collagen Expression in Osteoblasts
200169 citationsauthor #5
Anabolic actions of PTH in the skeletons of animals.
200122 citationsauthor #1
Intermittently Administered Human Parathyroid Hormone(1–34) Treatment Increases Intracortical Bone Turnover and Porosity Without Reducing Bone Strength in the Humerus of Ovariectomized Cynomolgus Monkeys
2001288 citationsauthor #6
Involvement of the nuclear matrix in the control of skeletal genes: the NMP1 (YY1), NMP2 (Cbfa1), and NMP4 (Nmp4/CIZ) transcription factors.
200133 citationsauthor #8
In vivo comparison of activated protein-1 gene activation in response to human parathyroid hormone (hPTH)(1-34) and hPTH(1-84) in the distal femur metaphyses of young mice.
200034 citationsauthor #3
The expression of the nuclear matrix proteins NuMA, topoisomerase II-α, and -β in bone and osseous cell culture: regulation by parathyroid hormone
200017 citationsauthor #6
Further Data are Required to Assure that the Discrepant Binding Affinity is Explained by Different Receptor Conformations
20000 citationsauthor #4
Changes in Geometry and Cortical Porosity in Adult, Ovary-Intact Rabbits after 5 Months Treatment with LY333334 (hPTH 1-34)
200092 citationsauthor #4
Discrimination among osteoblasts? Parathyroid hormone analog may reveal site-specific differences in mice.
20007 citationsauthor #1
The expression of the nuclear matrix proteins NuMA, topoisomerase II-alpha, and -beta in bone and osseous cell culture: regulation by parathyroid hormone.
20008 citationsauthor #6
In vivo regulation of apoptosis in metaphyseal trabecular bone of young rats by synthetic human parathyroid hormone (1-34) fragment.
200080 citationsauthor #11
Six‐Month Daily Administration of Parathyroid Hormone and Parathyroid Hormone—Related Protein Peptides to Adult Ovariectomized Rats Markedly Enhances Bone Mass and Biomechanical Properties: A Comparison of Human Parathyroid Hormone 1–34, Parathyroid Hormone‐Related Protein 1–36, and SDZ‐Parathyroid
2000129 citationsauthor #6
A method for increasing bone toughness and stiffness and reducing breakage
19990 citationsauthor #1
hPTH (1-34) for use in the prevention or reduction of the incidence or severity of vertebral and / or non-vertebral fractures in a man
19990 citationsauthor #1
Anabolic Effects of Human Biosynthetic Parathyroid Hormone Fragment (1–34), LY333334, on Remodeling and Mechanical Properties of Cortical Bone in Rabbits
1999165 citationsauthor #6
Molecular Characterization of Gene Expression Changes in ROS 17/2.8 Cells Cultured in Diffusion Chambers In Vivo
199913 citationsauthor #7
Parathyroid Hormone Regulates the Expression of Fibroblast Growth Factor‐2 mRNA and Fibroblast Growth Factor Receptor mRNA in Osteoblastic Cells
1999106 citationsauthor #4
Daily treatment with human recombinant parathyroid hormone-(1-34), LY333334, for 1 year increases bone mass in ovariectomized monkeys.
199998 citationsauthor #5
Assessment of maintenance therapy with reduced doses of PTH(1-34) in combination with a raloxifene analogue (LY117018) following anabolic therapy in the ovariectomized rat.
199920 citationsauthor #6
Comparison of Recombinant Human PTH(1–34) (LY333334) with a C‐Terminally Substituted Analog of Human PTH‐Related Protein(1–34) (RS‐66271): In Vitro Activity and In Vivo Pharmacological Effects in Rats
199947 citationsauthor #8
Use of parathyroid hormone consists of an amino acid sequence 1-34 of human parathyroid hormone to reduce riesco osseous vertebral and nonvertebral fractures.
19990 citationsauthor #1
Method of increasing the hardness and rigidity and bone fracture reduction
19990 citationsauthor #1
A method for increasing the knoglesejhed and stiffness and reduction of fractures
19990 citationsauthor #1
Method of increasing bone hardness and rigidity of bone and reduce fractures
19990 citationsauthor #1
Immunohistochemical Localization of Selected Early Response Genes Expressed in Trabecular Bone of Young Rats Given hPTH 1-34
199944 citationsauthor #2
Nuclear Matrix Proteins and Osteoblast Gene Expression
199878 citationsauthor #5
Effects of Human Parathyroid Hormone on Cortical Bone in Rabbits
19980 citationsauthor #6
Analysis of differential gene expression in rat tibia after an osteogenic stimulus in vivo: Mechanical loading regulates osteopontin and myeloperoxidase
199838 citationsauthor #12
PTH‐responsive osteoblast nuclear matrix architectural transcription factor binds to the rat type I collagen promoter
199837 citationsauthor #5
Intermittent administration of parathyroid hormone (1‐34) stimulates matrix metalloproteinase‐9 (MMP‐9) expression in rat long bone
199853 citationsauthor #8
Tissue matrix protein expression in human osteoblasts, osteosarcoma tumors, and osteosarcoma cell lines
19976 citationsauthor #8
Topoisomerase II expression in osseous tissue
199711 citationsauthor #5
Parathyroid hormone (1‐34)–mediated interleukin‐6 induction
199740 citationsauthor #7
Rat Osteoblast and Osteosarcoma Nuclear Matrix Proteins Bind with Sequence Specificity to the Rat Type I Collagen Promoter1.
199734 citationsauthor #4
Rat osteoblast and osteosarcoma nuclear matrix proteins bind with sequence specificity to the rat type I collagen promoter.
199728 citationsauthor #4
Parathyroid hormone regulates the expression of rat osteoblast and osteosarcoma nuclear matrix proteins
199614 citationsauthor #6
Growth hormone does not enhance the anabolic effect of human parathyroid hormone (1-34) on bone in aging multiparous and virgin rats.
19955 citationsauthor #1
Comparisons of in vivo and in vitro models of the response of osteoblasts to hormonal regulation with aging.
19950 citationsauthor #1
In vivo, human parathyroid hormone fragment (hPTH 1-34) transiently stimulates immediate early response gene expression, but not proliferation, in trabecular bone cells of young rats.
1995152 citationsauthor #5
Identification of osteocalcin mrna in nonosteoid tissue of rats and humans by reverse transcription—polymerase chain reaction
199494 citationsauthor #2
Parenteral pamidronate prevents thyroid hormone‐induced bone loss in rats
199331 citationsauthor #8
Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone
1992358 citationsauthor #1
A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide.
19911,211 citationsauthor #8
Transforming growth factor-beta stimulates bone matrix apposition and bone cell replication in cultured fetal rat calvariae.
1990160 citationsauthor #1
Transforming Growth Factor-β Stimulates Bone Matrix Apposition and Bone Cell Replication in Cultured Fetal Rat Calvariae*
199046 citationsauthor #1
Anabolic effect of human synthetic parathyroid hormone-(1-34) depends on growth hormone.
199076 citationsauthor #1
Resorption is not essential for the stimulation of bone growth by hPTH‐(1‐34) in rats in vivo
1989124 citationsauthor #1
Human parathyroid hormone-(1-34) increases bone mass in ovariectomized and orchidectomized rats.
1988245 citationsauthor #1
1,25 dihydroxyvitamin D3 alone or in combination with parathyroid hormone does not increase bone mass in young rats
19884 citationsauthor #5
Insulin-like growth factor I has independent effects on bone matrix formation and cell replication.
1988619 citationsauthor #1
Indomethacin does not inhibit the anabolic effect of parathyroid hormone on the long bones of rats
19874 citationsauthor #2
Colony-stimulating factors regulate the development of multinucleated osteoclasts from recently replicated cells in vitro.
198796 citationsauthor #4
Human parathyroid hormone (1–34) and salmon calcitonin do not reverse impaired mineralization produced by high doses of 1,25 dihydroxyvitamin D3
19863 citationsauthor #2
Stimulation of undermineralized matrix formation by 1,25 dihydroxyvitamin D3 in long bones of rats
198622 citationsauthor #1
Increased trabecular bone mass in rats treated with human synthetic parathyroid hormone.
1984206 citationsauthor #2
DNA synthesis is not necessary for osteoclastic responses to parathyroid hormone in cultured fetal rat long bones.
198360 citationsauthor #3
Autoradiographic study of the effect of 1,25-dihydroxyvitamin D3 on bone matrix synthesis in vitamin D replete rats
198212 citationsauthor #1
Use of osmotic minipumps for delivery of parathyroid hormone
19820 citationsauthor #1

TIMELINE

1982 12 citations

1983 60 citations

1984 206 citations

1986 25 citations

1987 100 citations

1988 868 citations

1989 124 citations

1990 282 citations

1991 1,211 citations

1992 358 citations

1993 31 citations

1994 94 citations

1995 157 citations

1996 14 citations

1997 119 citations

1998 206 citations

1999 493 citations

2000 367 citations

2001 914 citations

2002 101 citations

2003 472 citations

2004 424 citations

2005 9 citations

2006 254 citations

2008 12 citations

2009 175 citations

2010 127 citations

2012 119 citations

2013 102 citations

2014 50 citations

2016 52 citations

2019 1 citations

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