H. Salwen

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Aliases
Helen R. Salwen, Helen Salwen, Helen R Salwen, H R Salwen, H Salwen
Publication record
73 papers · 2,986 citations · H-index 35

PAPERS

Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation
202428 citationsauthor #15
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia
20226 citationsauthor #4
Abstract B02: 5-Hydroxymethylcytosine profiles in circulating cell-free DNA are biomarkers of disease burden in children with neuroblastoma
20200 citationsauthor #6
Maternal Embryonic Leucine Zipper Kinase (MELK), a Potential Therapeutic Target for Neuroblastoma
201927 citationsauthor #4
5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma
201932 citationsauthor #11
5-Hydroxymethylcytosine Profiles Are Prognostic of Outcome in Neuroblastoma and Reveal Transcriptional Networks That Correlate With Tumor Phenotype
201923 citationsauthor #11
Abstract PR16: Whole-genome analysis of the epigenetic mark 5-hydroxymethylcytosine reveals differential profiles in low- , intermediate- , and high-risk neuroblastomas
20180 citationsauthor #7
Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids
201620 citationsauthor #3
Abstract A01: Evaluation of hypoxia adaptation in neuroblastoma identifies reproducible transcriptional and phenotypic responses
20160 citationsauthor #8
Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients
201634 citationsauthor #6
Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse
201622 citationsauthor #6
Validation of a prognostic multi‐gene signature in high‐risk neuroblastoma using the high throughput digital NanoString nCounter™ system
201435 citationsauthor #5
Abstract 3607: Modulation of neuroblastoma metabolism by an extracellular chaperone SPARC
20140 citationsauthor #3
Abstract 1037: Histone lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, and DNA methylation of human neuroblastoma cells
20120 citationsauthor #2
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma.
201240 citationsauthor #10
Sorafenib inhibits neuroblastoma cell proliferation and signaling, blocks angiogenesis, and impairs tumor growth
201229 citationsauthor #7
Genome-based outcome prediction in MYCN nonamplified high-risk neuroblastoma.
20120 citationsauthor #12
Valproic acid shows a potent antitumor effect with alteration of DNA methylation in neuroblastoma
201248 citationsauthor #4
Molecular and Cellular Pathobiology Truncated DNMT 3 B Isoform DNMT 3 B 7 Suppresses Growth , Induces Differentiation , and Alters DNA Methylation in Human Neuroblastoma
20122 citationsauthor #10
Abstract 1040: A truncated DNMT3B protein (DNMT3B7) drives DNA methylation and suppresses growth in human neuroblastoma
20120 citationsauthor #7
The quinoxaline anti‐tumor agent (R+)XK469 inhibits neuroblastoma tumor growth
201122 citationsauthor #10
Secreted Protein Acidic and Rich in Cysteine Is a Matrix Scavenger Chaperone
201159 citationsauthor #3
ResearchSPARC peptides inhibit progression of neuroblastoma tumors
20100 citationsauthor #7
Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors
201055 citationsauthor #8
Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines
201027 citationsauthor #6
Presence Of Cancer-Associated Fibroblasts Inversely Correlates With Schwannian Stroma In Neuroblastoma Tumors
200953 citationsauthor #2
Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma.
200792 citationsauthor #6
SPARC enhances tumor stroma formation and prevents fibroblast activation
200752 citationsauthor #6
Methylation of CASP8, DCR2, and HIN-1 in Neuroblastoma Is Associated with Poor Outcome
2007112 citationsauthor #4
Prominent Microvascular Proliferation in Clinically Aggressive Neuroblastoma
200743 citationsauthor #8
Prominent vascular endothelial proliferation in clinically aggressive neuroblastoma
20070 citationsauthor #8
SPARC expression is associated with impaired tumor growth, inhibited angiogenesis and changes in the extracellular matrix
2006115 citationsauthor #6
SPARC enhances formation and prevents activation of tumor stroma
20060 citationsauthor #7
Suppression of malignant phenotype of human neuroblastoma by thrombospondin-1 peptide in combination with valproic acid
20060 citationsauthor #6
Cross-talk between Schwann cells and neuroblasts influences the biology of neuroblastoma xenografts.
200542 citationsauthor #6
'Cross-talk' between Schwannian stroma and neuroblasts promotes neuroblastoma tumor differentiation and inhibits angiogenesis.
200530 citationsauthor #5
Neuroblastoma Angiogenesis Is Inhibited with a Folded Synthetic Molecule Corresponding to the Epidermal Growth Factor-Like Module of the Follistatin Domain of SPARC
200456 citationsauthor #6
Methylation-Associated Silencing of the Heat Shock Protein 47 Gene in Human Neuroblastoma
200441 citationsauthor #6
MYCN-mediated regulation of the MRP1 promoter in human neuroblastoma
200484 citationsauthor #3
Association of Epigenetic Inactivation of RASSF1A with Poor Outcome in Human Neuroblastoma
200491 citationsauthor #6
Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma.
2003118 citationsauthor #4
SPARC is a key Schwannian-derived inhibitor controlling neuroblastoma tumor angiogenesis.
2002162 citationsauthor #8
Combined karyotyping, CGH and M‐FISH analysis allows detailed characterization of unidentified chromosomal rearrangements in Merkel cell carcinoma
200288 citationsauthor #7
Expression of the putative tumour suppressor gene, p73, in neuroblastoma and other childhood tumours.
20012 citationsauthor #5
Combined M‐FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines
200151 citationsauthor #6
Antiangiogenic therapy inhibits human neuroblastoma growth.
200117 citationsauthor #2
MYCN expression is not prognostic of adverse outcome in advanced-stage neuroblastoma with nonamplified MYCN.
2000111 citationsauthor #5
MYCN Expression I s N ot P rognostic o f A dverse O utcome i n Advanced-Stage N euroblastoma W ith N onamplified MYCN
20000 citationsauthor #5
Altered expression of the MYCN oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells
199975 citationsauthor #11
Effectiveness of the angiogenesis inhibitor TNP-470 in reducing the growth of human neuroblastoma in nude mice inversely correlates with tumor burden.
199963 citationsauthor #4
Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma.
199760 citationsauthor #8
Up-regulation of HOXC6, HOXD1, and HOXD8 homeobox gene expression in human neuroblastoma cells following chemical induction of differentiation.
199650 citationsauthor #2
673 Vascular endothelial growth factor expression in neuroblastoma cell lines correlates with tumor phenotype
19960 citationsauthor #3
Co‐amplification and concomitant high levels of expression of a DEAD box gene with MYCN in human neuroblastoma
199554 citationsauthor #2
Lack of correlation of N-myc gene amplification with prognosis in localized neuroblastoma: a Pediatric Oncology Group study.
199586 citationsauthor #5
Retinoic acid induced expression of homeobox genes in human neuroblastoma cells.
19942 citationsauthor #2
The biological effects of antisense N-myc expression in human neuroblastoma.
199466 citationsauthor #2
Evidence for molecular heterogeneity in human ganglioneuroblastoma.
199315 citationsauthor #2
Hox gene expression in differentiating human neuroblastoma cells.
199315 citationsauthor #3
Differential expression of N-myc in phenotypically distinct subclones of a human neuroblastoma cell line.
199166 citationsauthor #7
Differential expression of N-myc in phenotypically distinct subclones of a human neuroblastoma cell line.
199166 citationsauthor #6
Differential expression of N-myc in phenotypically distinct subclones of a human neuroblastoma cell line.
199166 citationsauthor #5
High levels of N-myc protein in a neuroblastoma cell line lacking N-myc amplification.
19917 citationsauthor #2
Analysis ofDNAPloidy andProliferative Activity inRelation toHistology andN-myc Amplification inNeuroblastoma
19900 citationsauthor #3
Analysis of DNA ploidy and proliferative activity in relation to histology and N-myc amplification in neuroblastoma.
199061 citationsauthor #3
Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification.
199098 citationsauthor #2
Characterization of a novel myeloma cell line, MM.1.
198969 citationsauthor #2
Establishment and characterization of a neuroendocrine skin carcinoma cell line.
1987101 citationsauthor #3
Monoclonal antibody 44-3A6 as a probe for a novel antigen found on human lung carcinomas with glandular differentiation.
198557 citationsauthor #4
714 EXPERIENCE IN THE PRENATAL DIAGNOSIS OF ARGININO-SUCCINIC ACID (ASA) URIA AND CITRULLINEMIA
19810 citationsauthor #2
Carnosinase Deficiency: a New Variant with High Residual Activity
198018 citationsauthor #4
Argininosuccinic aciduria: prenatal studies in a family at risk.
197923 citationsauthor #4
De novo trisomy 9pter leads to q13.
19770 citationsauthor #2

TIMELINE

1977 0 citations

1979 23 citations

1980 18 citations

1981 0 citations

1985 57 citations

1987 101 citations

1989 69 citations

1990 159 citations

1991 73 citations

1993 30 citations

1994 68 citations

1995 140 citations

1996 50 citations

1997 60 citations

1999 138 citations

2000 111 citations

2001 70 citations

2002 250 citations

2003 118 citations

2004 272 citations

2005 72 citations

2006 115 citations

2007 299 citations

2009 53 citations

2010 82 citations

2011 81 citations

2012 119 citations

2014 35 citations

2016 76 citations

2018 0 citations

2019 82 citations

2020 0 citations

2022 6 citations

2024 28 citations

H. Salwen

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