W. Sweeney

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Aliases
William E. Jr. Sweeney, W E Sweeney, W. E. Sweeney, William E. Jr Sweeney, William E Sweeney, William E. Sweeney, William Sweeney, William E Jr. Sweeney
Publication record
94 papers · 4,695 citations · H-index 39

PAPERS

Volumetric Imaging Approaches Reveal Unique Spatial Interactions Between Cysts and Vasculature in Polycystic Mouse Kidneys
20210 citationsauthor #4
Novel Treatments for Polycystic Kidney Disease
20192 citationsauthor #2
Therapies for Childhood Polycystic Kidney Disease
20181 citationsauthor #2
Emerging Therapies for Childhood Polycystic Kidney Disease
20177 citationsauthor #1
Tesevatinib ameliorates progression of polycystic kidney disease in rodent models of autosomal recessive polycystic kidney disease
201745 citationsauthor #1
Polycystic Kidney Disease, Autosomal Recessive
201665 citationsauthor #1
Table 1. [Molecular Genetic Testing Used in ARPKD].
20160 citationsauthor #1
Figure 1. [New approaches to the individual...].
20160 citationsauthor #1
Childhood Polycystic Kidney Disease
201522 citationsauthor #2
Identifying genetic modifiers of autosomal recessive polycystic kidney disease (1179.1)
20140 citationsauthor #5
Fibrocystin/polyductin and pathophysiology of autosomal recessive polycystic kidney disease
20130 citationsauthor #2
Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease.
2013150 citationsauthor #3
Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy
201359 citationsauthor #1
Smac-mimetic-induced epithelial cell death reduces the growth of renal cysts.
201349 citationsauthor #3
Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on "Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease".
20126 citationsauthor #3
HDAC6 Regulates Epidermal Growth Factor Receptor (EGFR) Endocytic Trafficking and Degradation in Renal Epithelial Cells
201276 citationsauthor #4
Role of genetic modifiers in an orthologous rat model of ARPKD.
201227 citationsauthor #3
G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease
201237 citationsauthor #10
Diagnosis and management of childhood polycystic kidney disease
2011104 citationsauthor #1
Loss of activator of G‐protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents
201140 citationsauthor #6
Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.
201044 citationsauthor #9
Chronic treatment with lisinopril decreases proliferative and apoptotic pathways in autosomal recessive polycystic kidney disease
201018 citationsauthor #6
Chronic blockade of 20-HETE synthesis reduces polycystic kidney disease in an orthologous rat model of ARPKD.
200927 citationsauthor #2
20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease.
200849 citationsauthor #2
Src inhibition ameliorates polycystic kidney disease.
2008156 citationsauthor #1
Renal cystic disease: new insights for the clinician.
200626 citationsauthor #2
Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD)
2006106 citationsauthor #1
Haplotype analysis improves molecular diagnostics of autosomal recessive polycystic kidney disease.
200538 citationsauthor #12
Chapter 125 – Embryogenesis and Anatomic Development of the Kidney
20048 citationsauthor #1
Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats.
200472 citationsauthor #2
Renal epithelial development in organotypic culture
200413 citationsauthor #3
EGF-related growth factors in the pathogenesis of murine ARPKD.
200454 citationsauthor #3
Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability.
200383 citationsauthor #1
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats.
2003142 citationsauthor #2
Polycystin-1 Distribution Is Modulated by Polycystin-2 Expression in Mammalian Cells*
200383 citationsauthor #8
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats.
2002490 citationsauthor #13
Role of CFTR in autosomal recessive polycystic kidney disease.
200137 citationsauthor #2
Segment-specific c-ErbB2 expression in human autosomal recessive polycystic kidney disease.
200133 citationsauthor #2
Generation and phenotype of cell lines derived from CF and non-CF mice that carry the H-2K(b)-tsA58 transgene.
200121 citationsauthor #2
A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease.
200172 citationsauthor #3
Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD.
200129 citationsauthor #1
Refinement of the PKHD1 interval and analysis of candidate expressed sequences
20010 citationsauthor #7
Renal dysfunction but not cystic change is ameliorated by neonatal epidermal growth factor in bpk mice
200123 citationsauthor #3
Expression of the orpk disease gene during kidney development and maturation
200110 citationsauthor #2
Can progression of autosomal dominant or autosomal recessive polycystic kidney disease be prevented?
200136 citationsauthor #3
Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor.
2000212 citationsauthor #1
Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease.
200062 citationsauthor #2
Cellular pathophysiology of cystic kidney disease: insight into future therapies.
199916 citationsauthor #4
New insights into the molecular pathophysiology of polycystic kidney disease.
1999127 citationsauthor #2
In vitro modulation of cyst formation by a novel tyrosine kinase inhibitor.
199943 citationsauthor #1
Rapid Publication Epidermal Growth Factor Receptor Activity Mediates Renal Cyst Formation in Polycystic Kidney Disease
19980 citationsauthor #2
Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease.
1998202 citationsauthor #2
Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease.
199812 citationsauthor #1
Morphological and functional characterization of a conditionally immortalized collecting tubule cell line.
199824 citationsauthor #2
Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease.
199884 citationsauthor #1
The role of hepatocyte growth factor (HGF) at progressive stages of metanephric development
19981 citationsauthor #1
Differential rescue of the renal and hepatic disease in an autosomal recessive polycystic kidney disease mouse mutant. A new model to study the liver lesion.
199742 citationsauthor #4
Efficacy of taxol in the orpk mouse model of polycystic kidney disease
199726 citationsauthor #3
Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA.
199644 citationsauthor #11
Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA.
199644 citationsauthor #12
Novel Madin Darby Canine Kidney cell clones exhibit unique phenotypes in response to morphogens
19964 citationsauthor #3
Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA.
199644 citationsauthor #10
Forefronts in Nephrology: The molecular basis of renal cystic disease: I. Abnormal Regulation Of Epithelial Cell Growth: Role of growth factors in cell proliferation
19951 citationsauthor #2
Epidermal growth factor receptor expression is abnormal in murine polycystic kidney.
1995152 citationsauthor #2
Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture.
199562 citationsauthor #2
1 alpha, 25-dihydroxyvitamin D3 receptor ontogenesis in fetal renal development.
199522 citationsauthor #4
Forefronts in Nephrology: The molecular basis of renal cystic disease
19951 citationsauthor #9
Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease.
199576 citationsauthor #3
Metabolic studies of rat renal tubule cells loaded with cystine: the cystine dimethylester model of cystinosis.
199539 citationsauthor #5
Biliary Epithelial Cells from Mice with Congenital Polycystic Kidney Disease Are Hyperresponsive to Epidermal Growth Factor
199543 citationsauthor #2
Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice.
1994391 citationsauthor #6
Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease
199376 citationsauthor #3
A new murine model of autosomal recessive polycystic kidney disease.
19935 citationsauthor #3
Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease.
1992105 citationsauthor #2
Pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease.
19924 citationsauthor #1
Localization of Arginine Biosynthetic Enzymes in Renal Proximal Tubules and Abundance of mRNA during Development
199125 citationsauthor #2
INTACT ORGAN CULTURE OF MURINE METANEPHROS
199121 citationsauthor #1
Polypeptide growth factors in metanephric growth and segmental nephron differentiation
199029 citationsauthor #2
polycystic kidney disease
198925 citationsauthor #2
Abundance of mRNAs encoding urea cycle enzymes in fetal and neonatal mouse liver.
198933 citationsauthor #3
In vitro modulation of tubular cyst regression in murine polycystic kidney disease.
198924 citationsauthor #2
Congenital murine polycystic kidney disease
198814 citationsauthor #2
Congenital murine polycystic kidney disease
198721 citationsauthor #4
Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity.
198722 citationsauthor #2
Regression of genetically determined polycystic kidney disease in murine organ culture
19865 citationsauthor #2
Cytosolic glucocorticoid receptor concentrations in isolated renal tubular and glomerular preparations
19862 citationsauthor #3
Partial characterization and ontogeny of renal cytosolic glucocorticoid receptors in mouse kidney.
198610 citationsauthor #3
Growth factor requirements of organogenesis in serum-free metanephric organ culture
198516 citationsauthor #2
Sodium-potassium ATPase activity mediates cyst formation in metanephric organ culture.
198552 citationsauthor #2
1573 REGRESSION OF CONGENITAL MURINE POLYCYSTIC KIDNEY DISEASE (PKD) IN METANEPHRIC ORGAN CULTURE (MOC)
19850 citationsauthor #2
Hydrocortisone-induced cystic metanephric maldevelopment in serum-free organ culture.
198446 citationsauthor #3
A new model of glucocorticoid-induced metanephric maldevelopment
19846 citationsauthor #2
Cyst formation in metanephric organ culture induced by cis-dichlorodiammineplatinum (II)
19838 citationsauthor #2
Congenital murine polycystic kidney disease II
year unknown10 citationsauthor #2

TIMELINE

1983 8 citations

1984 52 citations

1985 68 citations

1986 17 citations

1987 43 citations

1988 14 citations

1989 82 citations

1990 29 citations

1991 46 citations

1992 109 citations

1993 81 citations

1994 391 citations

1995 396 citations

1996 48 citations

1997 68 citations

1998 323 citations

1999 186 citations

2000 274 citations

2001 261 citations

2002 490 citations

2003 308 citations

2004 147 citations

2005 38 citations

2006 132 citations

2008 205 citations

2009 27 citations

2010 62 citations

2011 144 citations

2012 146 citations

2013 258 citations

2014 0 citations

2015 22 citations

2016 65 citations

2017 52 citations

2018 1 citations

2019 2 citations

2021 0 citations

Unknown 10 citations

W. Sweeney

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