E. Crawford

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Aliases
Erin Crawford, E L Crawford, Erin L Crawford, Erin L. Crawford, Erin L> Crawford
Publication record
95 papers · 1,154 citations · H-index 21

PAPERS

High penetrance rare variants underlying familial lung cancer risk: Insights from genetic epidemiology of lung cancer consortium.
20250 citationsauthor #16
Abstract 3815: High-penetrance rare variants underlying familial lung cancer risk: Insights from the Genetic Epidemiology of Lung Cancer Consortium
20250 citationsauthor #13
Abstract 2375: Investigating airway epithelial TP53 somatic mutation prevalence as a common risk factor for COPD and lung cancer
20250 citationsauthor #2
Abstract 4781: Evaluation of a TP53 biomarker for lung cancer risk in nasal brushings and peripheral blood
20240 citationsauthor #1
Abstract 7024: Development of quality control methods for reliable NGS measurement of methylation in cfDNA
20240 citationsauthor #2
Abstract 6104: EDRN Lung Team Project 2 validation of molecular biomarkers for the early detection of lung cancer in the setting of indeterminate pulmonary nodules
20240 citationsauthor #12
TP53 mutation prevalence in normal airway epithelium as a biomarker for lung cancer risk
20236 citationsauthor #2
NAD+ DEPLETION IN THE INTESTINAL EPITHELIUM RESULTS IN MITOCHONDRIAL DYSFUNCTION AND INFLUENCES THE PATHOGENESIS OF EXPERIMENTAL COLITIS
20233 citationsauthor #2
Use of Internal Standards to Develop Improved Methylation Detection in cfDNA
20230 citationsauthor #1
Abstract 529: SNAQ-SEQ™: Use of synthetic internal standards in conjunction with poisson exact test to call variants in contrived circulating tumor DNA specimens
20220 citationsauthor #2
Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
20220 citationsauthor #22
Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples
20227 citationsauthor #22
Microcystin-LR aerosol induces inflammatory responses in healthy human primary airway epithelium.
202228 citationsauthor #9
Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions
20210 citationsauthor #51
Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions
202125 citationsauthor #51
Deep oncopanel sequencing reveals fixation time- and within block position-dependent quality degradation in FFPE processed samples
20216 citationsauthor #22
Abstract 2525: Low frequency TP53 mutations in airway epithelial cells serve as lung cancer risk biomarker
20210 citationsauthor #2
Advancing NGS quality control to enable measurement of actionable mutations in circulating tumor DNA
202114 citationsauthor #4
Advancing quality-control for NGS measurement of actionable mutations in circulating tumor DNA
20215 citationsauthor #4
Abstract 2286: Use of a synthetic spike-in ladder to measure NGS library complexity
20210 citationsauthor #1
Abstract 4609: TP53, PIK3CA, and BRAF somatic mutations in airway epithelial field of injury associated with lung cancer risk
20200 citationsauthor #4
Platelet-T cell aggregates in lung cancer patients: Implications for thrombosis
202025 citationsauthor #7
Abstract 3537: Targeted deep sequencing of driver mutations in airway epithelial cells from smokers
20190 citationsauthor #3
Abstract 3539: Impact of formalin time on targeted NGS performance in FFPE tissue
20191 citationsauthor #2
Circulating Lactonase Activity but Not Protein Level of PON-1 Predicts Adverse Outcomes in Subjects with Chronic Kidney Disease
201923 citationsauthor #8
Chronic Low Dose Oral Exposure to Microcystin-LR Exacerbates Hepatic Injury in a Murine Model of Non-Alcoholic Fatty Liver Disease
201937 citationsauthor #13
Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells
201914 citationsauthor #4
Abstract 432: Novel method for NGS analysis of actionable mutations in circulating tumor DNA specimens: improved quality control and 20-fold lower sequencing required
20190 citationsauthor #2
RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs
201822 citationsauthor #4
Abstract 1488: Inter-individual variation in hTERT regulation pathway genes in normal bronchial epithelial cells
20181 citationsauthor #3
Abstract 1623: Inter-laboratory harmonization of next generation sequencing somatic mutation assays for cancer response prediction
20180 citationsauthor #3
Abstract 2222: Using rare variants to characterize lung cancer risk
20180 citationsauthor #4
A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells
20170 citationsauthor #2
Abstract 4737: A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells
20170 citationsauthor #2
A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells
20174 citationsauthor #2
ASSESSING NUCLECACDS AND ALLELES
20170 citationsauthor #1
Additional file 6: of Lung cancer risk test trial: study design, participant baseline characteristics, bronchoscopy safety, and establishment of a biospecimen repository
20160 citationsauthor #1
Haplotype and diplotype analyses of variation in ERCC5 transcription cis-regulation in normal bronchial epithelial cells.
201613 citationsauthor #2
Lung cancer risk test trial: study design, participant baseline characteristics, bronchoscopy safety, and establishment of a biospecimen repository
201612 citationsauthor #1
Abstract 2905: Induction of hTERT and increased proliferative potential in conditionally reprogrammed normal bronchial epithelial cells
20160 citationsauthor #5
Control for stochastic sampling variation and qualitative sequencing error in next generation sequencing analysis of KRAS actionable mutations
20166 citationsauthor #4
Abstract 2890: ERCC5 variant rs2296147 T-allele creates a predicted TP53 binding site and up-regulates transcript abundance in normal bronchial epithelial cells, while rs17655 C-allele is linked to miRNA binding site variant and down regulates
20168 citationsauthor #2
Additional file 4: of Lung cancer risk test trial: study design, participant baseline characteristics, bronchoscopy safety, and establishment of a biospecimen repository
20160 citationsauthor #1
Abstract 1983: Altered regulation of CEBP transcription factor family in normal bronchial epithelial cells of subjects with lung cancer or COPD
20160 citationsauthor #2
Control for stochastic sampling variation and qualitative sequencing error in next generation sequencing
201512 citationsauthor #2
Abstract 4259: Conversion of the Lung Cancer Risk Test (LCRT) to a next generation sequencing (NGS) platform
20150 citationsauthor #1
Abstract 4892: Methods for accurate reporting of confidence intervals in clinical applications of next generation sequencing (NGS)
20150 citationsauthor #1
Abstract 2205: Identification of transcript abundance difference at lung cancer and COPD risk genes in normal bronchial epithelial cells
20150 citationsauthor #3
Abstract 2084: Genetic variation at a cis-acting C/EBPG binding site is associated with allele-specific ERCC5 transcript expression
20150 citationsauthor #3
Abstract 3381: Investigation of C/EBPG transcription factor role in regulation of ERCC4 and ERCC5 in human lung cancer cells
20141 citationsauthor #3
A Multiplex Two-Color Real-Time PCR Method for Quality-Controlled Molecular Diagnostic Testing of FFPE Samples
201410 citationsauthor #2
Abstract 4251: Identification of expression quantitative trait loci at lung cancer and COPD risk genes in normal bronchial epithelial cells
20140 citationsauthor #1
Bioinformatics analysis of plant orthologous introns: identification of an intronic tRNA-like sequence.
20145 citationsauthor #5
Abstract 3401: Inter-individual variation in MUC5B allele specific expression in normal bronchial epithelial cells and relationship to lung cancer
20140 citationsauthor #3
Abstract 4156: Inter-individual variation in allele specific expression of catalase (CAT) in normal bronchial epithelial cells and association of putative cis-regulatory CAT SNP rs12807961 with lung cancer risk
20141 citationsauthor #3
Correction: Targeted RNA-Sequencing with Competitive Multiplex-PCR Amplicon Libraries
20134 citationsauthor #2
Abstract 61: Use of two-color fluorometric real-time PCR to develop molecular diagnostic tests with intrinsic quality control that augment cytomorphologic diagnosis of lung cancer.
20130 citationsauthor #2
Targeted RNA-Sequencing with Competitive Multiplex-PCR Amplicon Libraries
201339 citationsauthor #2
A new StaRT-PCR approach to detect and quantify fish Viral Hemorrhagic Septicemia virus (VHSv): enhanced quality control with internal standards.
201315 citationsauthor #3
Accurate Detection and Quantification of the Fish Viral Hemorrhagic Septicemia virus (VHSv) with a Two-Color Fluorometric Real-Time PCR Assay
201322 citationsauthor #6
CEBPG Exhibits Allele-Specific Expression in Human Bronchial Epithelial Cells
201311 citationsauthor #3
Abstract 4150: Quantitative sequencing following PCR-driven library preparation with internal standard mixtures has improved analytical performance and lower cost.
20131 citationsauthor #2
Quality control methods for optimal BCR-ABL1 clinical testing in human whole blood samples.
201314 citationsauthor #2
Abstract 5541: Molecular diagnostic tests to augment cytomorphologic diagnosis of lung cancer
20120 citationsauthor #2
Abstract 5538: Development of RNA quality control methods to improve BCR-ABL measurement in whole blood samples
20120 citationsauthor #2
Abstract 5549: Normal bronchial epithelial cells (NBEC) sample RNA quality characteristics that will yield reliable measurement of lung cancer risk test
20120 citationsauthor #2
Abstract 2232: Effectiveness evaluation of an in vitro nucleic acid amplification test for quantification of BCR-ABL fusion transcript variants in human whole blood
20110 citationsauthor #3
Evaluating tuberculosis case detection via real-time monitoring of tuberculosis diagnostic services.
201147 citationsauthor #4
Multi-Institutional Trial Of A Lung Cancer Risk Test
20100 citationsauthor #11
Cis-acting genetic variation at an E2F1/YY1 response site and putative p53 site is associated with altered allele-specific expression of ERCC5 (XPG) transcript in normal human bronchial epithelium.
201025 citationsauthor #2
Abstract 4988: Cis-acting genetic variation is associated with altered allele-specific expression of CEBPG transcript in normal human bronchial epithelium
20100 citationsauthor #3
Abstract 825: Development of RNA quality-control methods to improve tissue archiving and molecular diagnostic testing
20100 citationsauthor #2
Tuberculosis Evaluation And Management In District Health Centers In Rural Uganda
20100 citationsauthor #4
Pattern of antioxidant and DNA repair gene expression in normal airway epithelium associated with lung cancer diagnosis.
200955 citationsauthor #2
Identification of lung cancer risk biomarker candidates comprising transcript abundance levels of antioxidant, DNA repair, and transcription factor genes
20080 citationsauthor #3
CEBPG regulates ERCC5/XPG expression in human bronchial epithelial cells and this regulation is modified by E2F1/YY1 interactions.
200740 citationsauthor #1
Determination of lung cancer risk based on a biomarker comprising transcript abundance levels of 15 antioxidant and DNA repair genes
20070 citationsauthor #2
CEBPG transcription factor correlation with antioxidant and DNA repair genes in normal bronchial epithelial cells of individuals with and without bronchogenic carcinoma
20061 citationsauthor #2
Variation in transcriptional regulation of cyclin dependent kinase inhibitor p21waf1/cip1 among human bronchogenic carcinomas
2005110 citationsauthor #3
CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma
200537 citationsauthor #2
Standardized RT-PCR and the standardized expression measurement center.
200433 citationsauthor #2
Use of standardized reverse transcription-polymerase chain reaction and the standardized expression measurement center in multi-institutional trials to develop meaningful lung cancer classification based on molecular genetic criteria.
20046 citationsauthor #3
Development of a standardized, quantitative microarray for gene expression measurement
20041 citationsauthor #1
The c-myc x E2F-1/p21 interactive gene expression index augments cytomorphologic diagnosis of lung cancer in fine-needle aspirate specimens.
200313 citationsauthor #2
Genomics in smoking-induced lung injury
20030 citationsauthor #7
Multiplex standardized RT-PCR for expression analysis of many genes in small samples.
200221 citationsauthor #1
Reproducible Gene Expression Measurement Among Multiple Laboratories Obtained in a Blinded Study Using Standardized RT (StaRT)-PCR
20015 citationsauthor #1
Quantitative end-point RT-PCR gene expression measurement using the Agilent 2100 Bioanalyzer and standardized RT-PCR Application
20011 citationsauthor #1
Localization of tumor suppressor gene candidates by cytogenetic and short tandem repeat analyses in tumorigenic human bronchial epithelial cells.
20007 citationsauthor #5
Normal bronchial epithelial cell expression of glutathione transferase P1, glutathione transferase M3, and glutathione peroxidase is low in subjects with bronchogenic carcinoma.
200050 citationsauthor #1
Measurement of cytochrome P450 2A6 and 2E1 gene expression in primary human bronchial epithelial cells.
199860 citationsauthor #1
Loss of spr1 expression measurable by quantitative RT-PCR in human bronchogenic carcinoma cell lines.
199819 citationsauthor #3
Expression measurement of many genes simultaneously by quantitative RT-PCR using standardized mixtures of competitive templates.
1998101 citationsauthor #2
The gene expression index c-myc x E2F-1/p21 is highly predictive of malignant phenotype in human bronchial epithelial cells.
199842 citationsauthor #4
Molecular Cancer Stable Low-level Expression of P21 Waf1/cip1 in A549 Human Bronchogenic Carcinoma Cell Line-derived Clones Down-regulates E2f1 Mrna and Restores Cell Proliferation Control
year unknown86 citationsauthor #3

TIMELINE

1998 222 citations

2000 57 citations

2001 6 citations

2002 21 citations

2003 13 citations

2004 40 citations

2005 147 citations

2006 1 citations

2007 40 citations

2008 0 citations

2009 55 citations

2010 25 citations

2011 47 citations

2012 0 citations

2013 106 citations

2014 17 citations

2015 12 citations

2016 39 citations

2017 4 citations

2018 23 citations

2019 75 citations

2020 25 citations

2021 50 citations

2022 35 citations

2023 9 citations

2024 0 citations

2025 0 citations

Unknown 86 citations

E. Crawford

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