H. Hong

PROFILE

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Aliases
H. S. Hong, Hyun-seok Hong, H. Hong, Hyun‐seok Hong, Hyun Seok Hong
Publication record
50 papers · 3,134 citations · H-index 30

PAPERS

Discovery of an Orally Bioavailable Benzofuran Analogue That Serves as a β-Amyloid Aggregation Inhibitor for the Potential Treatment of Alzheimer's Disease.
201830 citationsauthor #11
Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design.
201740 citationsauthor #12
The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis
20160 citationsauthor #5
The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer’s disease pathogenesis
201622 citationsauthor #5
PiB-PET Imaging-Based Serum Proteome Profiles Predict Mild Cognitive Impairment and Alzheimer’s Disease
201630 citationsauthor #8
A novel porcine model of Alzheimer"s disease based on lentivirus vector-mediated gene transfer
20160 citationsauthor #2
Tomoregulin (TMEFF2) Binds Alzheimer’s Disease Amyloid-β (Aβ) Oligomer and AβPP and Protects Neurons from Aβ-Induced Toxicity
201516 citationsauthor #1
Hippocampal Slices Dendritic Spine Density and LTP Induction in Cultured
20150 citationsauthor #4
Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90
201536 citationsauthor #12
3D Light-Sheet Fluorescence Microscopy of Cranial Neurons and Vasculature during Zebrafish Embryogenesis
201527 citationsauthor #5
Mitochondrial ATP synthase activity is impaired by suppressed O-GlcNAcylation in Alzheimer's disease.
201581 citationsauthor #7
Identification of disulfide cross-linked tau dimer responsible for tau propagation
201563 citationsauthor #5
6-Phenoxy-2-phenylbenzoxazoles, novel inhibitors of receptor for advanced glycation end products (RAGE).
201512 citationsauthor #6
O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment.
2013105 citationsauthor #5
Two β-strands of RAGE participate in the recognition and transport of amyloid-β peptide across the blood brain barrier.
201316 citationsauthor #8
The Influence of Spin-Labeled Fluorene Compounds on the Assembly and Toxicity of the Aβ Peptide
201218 citationsauthor #6
Intracellular Amyloid-β Accumulation in Calcium-Binding Protein-Deficient Neurons Leads to Amyloid-β Plaque Formation in Animal Model of Alzheimer's Disease
201256 citationsauthor #2
Impaired Short-Term Plasticity in Mossy Fiber Synapses Caused by Mitochondrial Dysfunction of Dentate Granule Cells Is the Earliest Synaptic Deficit in a Mouse Model of Alzheimer's Disease
201280 citationsauthor #5
Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death
2012224 citationsauthor #4
Aβ1–42-RAGE Interaction Disrupts Tight Junctions of the Blood–Brain Barrier Via Ca2+-Calcineurin Signaling
2012239 citationsauthor #2
Ligand-based design, synthesis, and biological evaluation of 2-aminopyrimidines, a novel series of receptor for advanced glycation end products (RAGE) inhibitors.
201254 citationsauthor #8
Ghrelin Ameliorates Cognitive Dysfunction and Neurodegeneration in Intrahippocampal Amyloid-β1-42 Oligomer-Injected Mice
2011130 citationsauthor #4
Human Serum Transthyretin Levels Correlate Inversely with Alzheimer's Disease
201181 citationsauthor #5
A differential association of Apolipoprotein E isoforms with the amyloid‐β oligomer in solution
201150 citationsauthor #2
Single-cell mechanics provides a sensitive and quantitative means for probing amyloid-β peptide and neuronal cell interactions
201079 citationsauthor #3
FK506 Reduces Amyloid Plaque Burden and Induces MMP-9 in AβPP/PS1 Double Transgenic Mice
201049 citationsauthor #1
Candidate anti-A beta fluorene compounds selected from analogs of amyloid imaging agents.
201024 citationsauthor #1
Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons.
200928 citationsauthor #6
Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo
200967 citationsauthor #1
RAGE regulates BACE1 and Aβ generation via NFAT1 activation in Alzheimer's disease animal model
2009124 citationsauthor #4
AMYLOID-PEPTIDE ACCELERATES ALTERATIONS OF EXPRESSION AND LOCALIZATION OF TIGHT JUNCTION PROTEINS VIA RAGE
20090 citationsauthor #3
Syntheses of tricyclic pyrones and pyridinones and protection of Abeta-peptide induced MC65 neuronal cell death.
200916 citationsauthor #2
P1‐450: Tomoregulin‐2 binds beta‐amyloid precursor protein and intracellular beta‐amyloid (Aβ)
20081 citationsauthor #2
P2‐331: Counteraction of protein misfolding in Alzheimer's disease
20080 citationsauthor #3
Congo red and thioflavin-T analogs detect Abeta oligomers.
200888 citationsauthor #2
Congo red and thioflavin‐T analogs detect Aβ oligomers
2007199 citationsauthor #2
Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity.
200759 citationsauthor #1
Upregulation of amyloid precursor protein by platelet-derived growth factor in hippocampal precursor cells
20078 citationsauthor #3
Mapping the structural transition in an amyloidogenic apolipoprotein A-I.
200747 citationsauthor #4
Effect of Ischemic Neuronal Insults on Amyloid Precursor Protein Processing
200628 citationsauthor #3
ERK1/2 is an endogenous negative regulator of the γsecretase activity
200673 citationsauthor #3
A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid‐β oligomeric complexes
200691 citationsauthor #2
Amyloid peptide attenuates the proteasome activity in neuronal cells.
2005154 citationsauthor #2
Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity.
2004125 citationsauthor #2
Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice.
2003125 citationsauthor #3
Contribution of presenilin/gamma-secretase to calsenilin-mediated apoptosis.
200314 citationsauthor #3
Interferon gamma stimulates beta-secretase expression and sAPPbeta production in astrocytes.
200380 citationsauthor #1
Contribution of presenilin/γ-secretase to calsenilin-mediated apoptosis
200328 citationsauthor #3
Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice
2001145 citationsauthor #2
Neuroprotective effects of estrogen against beta-amyloid toxicity are mediated by estrogen receptors in cultured neuronal cells.
200174 citationsauthor #5

TIMELINE

2001 219 citations

2003 247 citations

2004 125 citations

2005 154 citations

2006 192 citations

2007 313 citations

2008 89 citations

2009 235 citations

2010 152 citations

2011 261 citations

2012 671 citations

2013 121 citations

2015 235 citations

2016 52 citations

2017 40 citations

2018 30 citations

H. Hong

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