G. Christé

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Aliases
G. Christe, Georg Christé, G Christé, G. C. Christe, Georges Christé, G Christe, Georges Christe
Publication record
86 papers · 915 citations · H-index 15

PAPERS

Genetic associations of protein-coding variants in human disease
2021117 citationsauthor #14
Divergent estimates of ratio between Na+-Ca2+ current densities in t-tubular and surface membranes of rat cardiomyocytes.
20212 citationsauthor #4
Accounting for cardiac t-tubule increase with age and myocyte volume to improve measurements of its membrane area and ionic current densities.
20203 citationsauthor #1
A Novel PITX2c Gain-of-Function Mutation, p.Met207Val, in Patients With Familial Atrial Fibrillation.
201919 citationsauthor #11
Different Densities of Na-Ca Exchange Current in T-Tubular and Surface Membranes and Their Impact on Cellular Activity in a Model of Rat Ventricular Cardiomyocyte
201711 citationsauthor #3
A modified mathematical model of human ventricular cardiomyocyte incorporating separate t-tubular and surface dyads and submembrane spaces
20170 citationsauthor #3
Acute effects of ethanol on action potential and intracellular Ca2+ transient in cardiac ventricular cells: a simulation study
201610 citationsauthor #3
Acute effects of ethanol on action potential and intracellular Ca2+ transient in cardiac ventricular cells: a simulation study
20152 citationsauthor #3
Effect of ethanol on action potential in ventricularcardiomyocytes: experimental and computational approach
20140 citationsauthor #3
SENSITIVITY OF ACTION POTENTIAL TO CHANGES OF INWARD RECTIFIERPOTASSIUM CURRENT IK1 IS DIFFERENT IN RECENT MODELS OF HUMANVENTRICULAR CARDIOMYOCYTES
20140 citationsauthor #3
The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT.
20146 citationsauthor #10
Characterization of novel KCNH 2 mutations in the l ong QT s yndrome type 2 manifesting as seizure s
20140 citationsauthor #3
Ranolazine accelerates amiodarone-mediated conversion of paroxysmal atrial fibrillation in man
20130 citationsauthor #31
Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation
201325 citationsauthor #5
EFFECT OF ION CONCENTRATION CHANGES IN T-TUBULES ON INTRACELLULAR SIGNALS CONTROLLING MECHANICAL ACTIVITY IN A MODEL OF HUMAN VENTRICULAR CARDIOMYOCYTE
20130 citationsauthor #4
Effect of Ion Concentration Changes in the Limited Extracellular Spaces on Sarcolemmal Ion Transport and Ca2+ Turnover in a Model of Human Ventricular Cardiomyocyte
201311 citationsauthor #4
Sudden Death of Cardiac Origin and Psychotropic Drugs
201245 citationsauthor #5
Unprovoked atrial tachyarrhythmias in aging spontaneously hypertensive rats: the role of the autonomic nervous system.
201249 citationsauthor #8
Effect of ion concentration changes in t-tubules on membranecurrents and intracellular Ca2+ transient in a model of humanventricular cardiomyocyte
20120 citationsauthor #4
Physiological consequences of ion concentration changes intransverse-axial tubular system in a model of human ventricularcardiomyocyte
20101 citationsauthor #4
VE-Cadherin Tyrosine Phosphorylation in Angiogenic and Quiescent Adult Tissues
20090 citationsauthor #5
Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures.
200930 citationsauthor #3
Modelling the cardiac transverse-axial tubular system.
200833 citationsauthor #3
A model of the guinea-pig ventricular cardiac myocyte incorporating a transverse-axial tubular system.
200860 citationsauthor #4
Modelling in cardiac electrophysiology
20083 citationsauthor #2
In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant.
200827 citationsauthor #7
Quantification of t-tubule area and protein distribution in rat cardiac ventricular myocytes.
200881 citationsauthor #6
Changes in action potentials and intracellular ionic homeostasis in a ventricular cell model related to a persistent sodium current in SCN5A mutations underlying LQT3.
20086 citationsauthor #1
A new C-terminal hERG mutation A915fs+47X associated with symptomatic LQT2 and auditory-trigger syncope.
200812 citationsauthor #1
Modelling t-tubule function in cardiac ventricular myocytes
20070 citationsauthor #2
Activity-dependent changes of [Ca 2+ ] in the transverse-axial tubular system reduce SR [Ca 2+ ] content and [Ca 2+ ] transient amplitude in rat and guinea pig cardiac ventricular myocytes: a simulation study
20060 citationsauthor #4
The functional role of cardiac T-tubules explored in a model of rat ventricular myocytes
200648 citationsauthor #3
Brain death does not change epicardial action potentials and their response to ischemia-reperfusion in open-chest pigs.
20063 citationsauthor #1
Voltage homogenity over the membrane of cardiac cell with atransverse-axial tubular system
20060 citationsauthor #1
The functional role of cardiac T-tubules in a model of rat ventricular myocytes
20065 citationsauthor #3
Evaluation of cardiac cell membrane capacitance from the current response to a small pulse. Compared reliability of numerical integration versus fitting an exponential decay
20061 citationsauthor #5
Cycling of cations between T-tubular and surface membranes in amodel of guinea-pig ventricular cardiomyocyte
20052 citationsauthor #1
Vascular Endothelial–Cadherin Tyrosine Phosphorylation in Angiogenic and Quiescent Adult Tissues
2005134 citationsauthor #5
PC 1 THE COHESIVE FORCE OF WATER
20050 citationsauthor #7
A novel quantitative description of electrophysiologicalprocesses in guinea pig ventricular cardiomyocytes
20050 citationsauthor #2
Effects of a persistent sodium current through mutated hnav1.5 sodium channels on intracellular ionic homeostasis in a ventricular cell model
20052 citationsauthor #1
Physiological role of transverse-axial tubular system in cardiac ventricular myocytes: a simulation study
20051 citationsauthor #4
Quantitative exploration of T-tubular membrane parameters in amodel of rat ventricular cardiomyocyte
20050 citationsauthor #4
Distribution of ionic concentrations in tubular system ofcardiomyocytes
20040 citationsauthor #3
Modelling the distribution of [Ca2+] within the cardiact-tubule: effects of Ca2+ current distribution and changes inextracellular [Ca2+]
20045 citationsauthor #3
Quantitative analysis of ionic concentration changes in tubularsystem of guinea pig ventricular cardiomyocyte
20040 citationsauthor #2
Concentration changes in Ca2+ and K+ in the t-tubules of ratand guinea pig as estimated in two models of ventricularmyocytes
20040 citationsauthor #1
Ion concentration changes in transverse-axial tubular system ofrat and guinea pig ventricular cardiomyocytes: a simulationstudy
20040 citationsauthor #2
MODELLING THE DISTRIBUTION OF [Ca 2+ ] WITHIN THE CARDIAC T-TUBULE - EFFECTS OF Ca 2+ CURRENT DISTRIBUTION AND CHANGES IN EXTRACELLULAR [Ca 2+ ]
20043 citationsauthor #2
Changes of [Ca2+] in the t-tubule lumen during activity maymodulate the inotropic state of rat cardiac ventricularmyocytes
20040 citationsauthor #2
Physiological consequences of ionic concentration changes incardiac cell tubular System
20040 citationsauthor #2
MODELLING CHANGES OF [Ca 2+ ] AND [K + ] IN THE T-TUBULES OF RAT AND GUINEA PIG VENTRICULAR MYOCYTES
20041 citationsauthor #3
Ionic concentration changes in the tubular system of ratventricular cardiac cell model
20040 citationsauthor #2
Effects of chronic treatment with glibenclamide and/or metformin on the resistance to ischaemia of isolated hearts from Zucker Diabetic Fatty rats (ZDF/GMI-fa/fa)
20033 citationsauthor #2
Impact of T-tubules on electrical activity of cardiac cellsevaluated in a quantitative model
20030 citationsauthor #2
Quantitative modelling of effect of transverse - axial tubularsystem on electrical activity of cardiac cells: Development ofmodel II.
20031 citationsauthor #2
A quantitative model of the cardiac ventricular cell incorporating the transverse-axial tubular system.
200314 citationsauthor #2
Role of TAT-system in cardiac excitability: investigation in aquantitative model of a ventricular cardiac cell
20020 citationsauthor #2
The role of transverse-axial tubular system in ventricularcardiac cell arrhythmogenesis: A simulation study
20020 citationsauthor #2
Effect of series resistance, seal resistance and leakresistance on membrane current-voltage relations measured inwhole cell patch clamp arrangement
20020 citationsauthor #2
Arrhythmogenic effect of extracellular K-depletion is preventedby the transverse-axial tubular system in a ventricular cardiaccell model
20021 citationsauthor #2
Quantitative modelling of effect of transverse-axial tubularsystem on electrical activity of cardiac cells under low [K]e)
20020 citationsauthor #2
Computer modelling of effect of transversal tubules onexcitation - contraction coupling in cardiac cells (Basicstudy)
20011 citationsauthor #2
Electrophysiological analysis of the negative chronotropic effect of endothelin‐1 in rabbit sinoatrial node cells
200117 citationsauthor #4
Quantitative analysis and modelling of membrane currents incardiac cells
20000 citationsauthor #2
Propafenone blocks ATP-sensitive K+ channels in rabbit atrial and ventricular cardiomyocytes.
199915 citationsauthor #1
Localization of K(+) channels in the tubules of cardiomyocytes as suggested by the parallel decay of membrane capacitance, IK(1) and IK(ATP) during culture and by delayed IK(1) response to barium.
199941 citationsauthor #1
Does propafenone block open sodium channels
19980 citationsauthor #5
Off-line correction of artefacts in whole-cell recordings oftime-independent ionic currents. Application to the IKATPcurrent of cardiac myocytes.
19980 citationsauthor #1
Interaction of ATP-sensitive potassium channels with antiarrhythmic drugs. The effect of propafenone.
19980 citationsauthor #1
Kinetics of propafenone-induced block of sodium current in ratventricular myocytes
19973 citationsauthor #5
Therapeutic levels of antiarrhythmic agent propafenone inhibitATP-sensitive channels in rabbit myocardial cells.
19971 citationsauthor #1
Propafenone is a pure blocker of rabbit cardiac ATPi-sensitiveK current
19970 citationsauthor #5
A modulated receptor model to account for time- anduse-dependent 4-aminopyridine blockade of dog ventriculartransient outward current.
19960 citationsauthor #1
A biophysically realistic model accounts for control featuresand 4-AP inhibition of dog cardiac transient outward current.
19960 citationsauthor #1
Control of cardiac performance by Ca-turnover
19960 citationsauthor #4
A discrete model of the beat to beat control of mechanical activity in cardiac cell
19950 citationsauthor #4
Use-dependent features of 4-aminopyridine block of transient outward current in rat ventricular myocytes.
19957 citationsauthor #1
Use-dependent 4-aminopyridine blodk of cardiac transient outward current.
19950 citationsauthor #1
A model of the "beat to beat" control of contraction of cardiac cell and its interpretation
19950 citationsauthor #4
Presence of a Cs-resistant transient outward current which distorts ICa measurements in guinea-pig single ventricular cells
19891 citationsauthor #1
Use-dependent effects of 4-aminopyridine on transient outward current in dog ventricular muscle
19898 citationsauthor #3
Membrane responses to large hyperpolarizations in trabecles and single cells of frog atrium.
19885 citationsauthor #2
An in vitro evaluation of the hemostatic activity of topical agents.
198811 citationsauthor #3
Possible role of Na+ ions in intracellular Ca2+ release in frog auricular trabeculae.
19854 citationsauthor #2
Effects of low [K+]o on the electrical activity of human cardiac ventricular and Purkinje cells.
198325 citationsauthor #1

TIMELINE

1983 25 citations

1985 4 citations

1988 16 citations

1989 9 citations

1995 7 citations

1996 0 citations

1997 4 citations

1998 0 citations

1999 56 citations

2000 0 citations

2001 18 citations

2002 1 citations

2003 18 citations

2004 9 citations

2005 139 citations

2006 57 citations

2007 0 citations

2008 222 citations

2009 30 citations

2010 1 citations

2012 94 citations

2013 36 citations

2014 6 citations

2015 2 citations

2016 10 citations

2017 11 citations

2019 19 citations

2020 3 citations

2021 119 citations

COAUTHOR MAP

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