M. Bictash

PROFILE

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Aliases
Magda N. Bictash, M Bictash, Magda N Bictash, Magda Bictash, M. Bictash
Publication record
42 papers · 3,513 citations · H-index 17

PAPERS

Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
202246 citationsauthor #15
Structural Analysis and Development of Notum Fragment Screening Hits
20224 citationsauthor #16
Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit
202212 citationsauthor #19
TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation
20215 citationsauthor #5
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
202125 citationsauthor #13
Author response: Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
20210 citationsauthor #13
TREM2/PLCγ2 signalling in immune cells: function, structural insight, and potential therapeutic modulation
202144 citationsauthor #5
Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity.
20218 citationsauthor #11
Structural Insights into Notum Covalent Inhibition
202113 citationsauthor #6
Screening of a custom-designed acid fragment library identifies 1-phenylpyrroles and 1-phenylpyrrolidines as inhibitors of Notum carboxylesterase activity.
202016 citationsauthor #17
5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit.
202014 citationsauthor #13
Changing the HTS Paradigm: AI-Driven Iterative Screening for Hit Finding
202043 citationsauthor #2
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at Chr16q11.2 and on the MAPT H1 allele
202011 citationsauthor #13
Publisher Correction: Molecular and functional variation in iPSC-derived sensory neurons
20190 citationsauthor #12
Publisher Correction: Molecular and functional variation in iPSC-derived sensory neurons
20190 citationsauthor #12
STRUCTURE OF THE WNT DEACYLASE NOTUM IN COMPLEX WITH A BENZOTRIAZOLE FRAGMENT
20195 citationsauthor #12
Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors
201916 citationsauthor #12
Characterisation of the CNS expression and function of Notum, a negative regulator of Wnt signalling pathway.
20180 citationsauthor #6
Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration
2018589 citationsauthor #15
Molecular and functional variation in iPSC-derived sensory neurons
2017203 citationsauthor #12
Molecular and functional variation in iPSC-derived sensory neurons
20171 citationsauthor #12
Application of induced pluripotent stem cell technology for disease modelling and drug discovery in peripheral sensory neurons
20170 citationsauthor #2
Molecular and functional variation in iPSC-derived sensory 1 neurons 2
20170 citationsauthor #14
The discovery and evaluation of diaryl ether heterocyclic sulfonamides as URAT1 inhibitors for the treatment of gout
20167 citationsauthor #7
Targeting the cAMP and Transforming Growth Factor‐β Pathway Increases Proliferation to Promote Re‐Epithelialization of Human Stem Cell‐Derived Retinal Pigment Epithelium
201615 citationsauthor #7
The design, synthesis and evaluation of low molecular weight acidic sulfonamides as URAT1 inhibitors for the treatment of gout
20166 citationsauthor #6
Urinary metabolic signatures of human adiposity
2015195 citationsauthor #6
Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research
201426 citationsauthor #11
Metabolic phenotyping in epidemiology and metabolome-wide association studies
20140 citationsauthor #1
Characterizing Human Stem Cell-derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research.
2014107 citationsauthor #11
Quantitative UPLC-MS/MS analysis of the gut microbial co-metabolites phenylacetylglutamine, 4-cresyl sulphate and hippurate in human urine: INTERMAP Study.
201235 citationsauthor #3
In vitro and in vivo pharmacological characterisation of the potent and selective vasopressin V(1A) receptor antagonist 4-[4-(4-Chloro-phenyl)-5-[1,2,3]triazol-2-ylmethyl-4H-[1,2,4]triazol-3-yl]-piperidin-1-yl-(3,5-difluoro-phenyl) methanone (PF-00738245).
20113 citationsauthor #8
Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology.
2010142 citationsauthor #1
Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study.
2010123 citationsauthor #6
Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption.
2010257 citationsauthor #4
Correction
20100 citationsauthor #19
Integrated Cytokine and Metabolic Analysis of Pathological Responses to Parasite Exposure in Rodents
201043 citationsauthor #9
Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies.
200937 citationsauthor #6
Metabolic Profiling and Population Screening of Analgesic Usage in NMR-Spectroscopy-based Large-scale Epidemiologic Studies
20090 citationsauthor #6
Biomarkers in nutritional epidemiology: applications, needs and new horizons
2009432 citationsauthor #3
Human metabolic phenotype diversity and its association with diet and blood pressure
20081,031 citationsauthor #4
Exploring the Contribution of Metabolic Profiling to Epidemiological Studies
20080 citationsauthor #1

TIMELINE

2008 1,031 citations

2009 469 citations

2010 565 citations

2011 3 citations

2012 35 citations

2014 133 citations

2015 195 citations

2016 28 citations

2017 204 citations

2018 589 citations

2019 21 citations

2020 84 citations

2021 95 citations

2022 62 citations

M. Bictash

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