N. Holliday

PROFILE

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Aliases
N D Holliday, Nicholas D Holliday, Nicholas Holliday, Nicholas D. Holliday
Publication record
68 papers · 2,234 citations · H-index 24

PAPERS

Role of G protein‐coupled receptor kinases (GRKs) in β2‐adrenoceptor‐mediated glucose uptake
20241 citationsauthor #7
A time-resolved Förster resonance energy transfer assay to investigate drug and inhibitor binding to ABCG2.
20241 citationsauthor #6
Dually Labeled Neurotensin NTS1R Ligands for Probing Radiochemical and Fluorescence-Based Binding Assays
20243 citationsauthor #15
Correction to "Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta".
20232 citationsauthor #17
A time-resolved Förster resonance energy transfer assay to investigate inhibitor binding to ABCG2
20230 citationsauthor #6
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
20230 citationsauthor #73
Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2
202310 citationsauthor #6
Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
202232 citationsauthor #15
Optical control of the β2-adrenergic receptor with opto-prop-2: A cis-active azobenzene analog of propranolol
202212 citationsauthor #13
Development of gallium coordinate nonapeptides as candidates for PET imaging of neuropeptide Y1 receptors in oncology
20220 citationsauthor #4
Bitter taste sensitivity in domestic dogs (Canis familiaris) and its relevance to bitter deterrents of ingestion
202210 citationsauthor #9
Development of fluorescent peptide G Protein Coupled Receptor activation biosensors for NanoBRET characterisation of intracellular allosteric modulators
20225 citationsauthor #4
Luciferase Complementation Approaches to Measure GPCR Signaling Kinetics and Bias.
202113 citationsauthor #3
Analysis of Sequence Divergence in Mammalian ABCGs Predicts a Structural Network of Residues That Underlies Functional Divergence
20217 citationsauthor #3
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
2021438 citationsauthor #67
The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex
202037 citationsauthor #29
Investigating the Kinetics of β1 and β2 Adrenoceptor Effector Recruitment using Luciferase Complementation Assays
20200 citationsauthor #2
Using NanoBit complementation and TR FRET to Study the Mechanism of Action of Small‐molecule Modulators of CXCR2
20201 citationsauthor #4
is an essential subunit of an ADAM10 scissor complex
20200 citationsauthor #31
Red-emitting dibenzodiazepinone derivatives as fluorescent dualsteric probes for the muscarinic acetylcholine M2 receptor.
202015 citationsauthor #11
Application of fluorescence correlation spectroscopy to study substrate binding in styrene maleic acid lipid copolymer encapsulated ABCG2
202018 citationsauthor #3
Kinetics of ligand binding and signaling
20203 citationsauthor #3
is an essential subunit of an ADAM10 scissor complex
20201 citationsauthor #31
Heterodimeric analogues of the potent Y1R antagonist 1229U91, lacking one of the pharmacophoric C-terminal structures, retain potent Y1R affinity and show improved selectivity over Y4R.
20202 citationsauthor #6
ThermoBRET: a ligand-engagement nanoscale thermostability assay applied to GPCRs
20203 citationsauthor #9
Fluorescence Labeling of Neurotensin(8–13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity
201924 citationsauthor #11
The Peptide PnPP-19, a Spider Toxin Derivative, Activates μ-Opioid Receptors and Modulates Calcium Channels
201818 citationsauthor #9
Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors
2017180 citationsauthor #4
Plasma membrane dynamics and tetrameric organisation of ABCG2 transporters in mammalian cells revealed by single particle imaging techniques.
201653 citationsauthor #3
Identification of a Cyanine-Dye Labeled Peptidic Ligand for Y1R and Y4R, Based upon the Neuropeptide Y C-Terminal Analogue, BVD-15.
20169 citationsauthor #7
Optically Pure, Structural, and Fluorescent Analogues of a Dimeric Y4 Receptor Agonist Derived by an Olefin Metathesis Approach.
201616 citationsauthor #5
Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data.
201641 citationsauthor #3
Single Molecule or Ensemble Fluorescence Microscopy Investigations of ABC Transporter Oligomerisation and Dynamics
20161 citationsauthor #2
Kilpatrick, Laura E. and Briddon, Stephen J. and Holliday, Nicholas D. (2012) Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane
20160 citationsauthor #2
Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network*
201539 citationsauthor #4
A G Protein–Coupled Receptor Dimer Imaging Assay Reveals Selectively Modified Pharmacology of Neuropeptide Y Y1/Y5 Receptor Heterodimers
201526 citationsauthor #3
Propargyloxyproline Regio- and Stereoisomers for Click-Conjugation of Peptides: Synthesis and Application in Linear and Cyclic Peptides
20158 citationsauthor #7
Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis
201416 citationsauthor #10
Synthetic routes to the Neuropeptide Y Y1 receptor antagonist 1229U91 and related analogues for SAR studies and cell-based imaging.
20148 citationsauthor #6
Investigation of the novel pharmacology of Neuropeptide Y (NPY) receptor dimers constrained by bimolecular fluorescence complementation (BiFC)
20130 citationsauthor #2
The Arginine of the DRY Motif in Transmembrane Segment III Functions as a Balancing Micro-switch in the Activation of the β2-Adrenergic Receptor
201239 citationsauthor #5
Differential Signaling by Splice Variants of the Human Free Fatty Acid Receptor GPR120
2012142 citationsauthor #3
Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptors
201240 citationsauthor #3
Dissecting the pharmacology of G protein-coupled receptor signaling complexes using bimolecular fluorescence complementation.
201212 citationsauthor #2
Dimerization of ABCG2 Analysed by Bimolecular Fluorescence Complementation
201134 citationsauthor #5
Unique Interaction Pattern for a Functionally Biased Ghrelin Receptor Agonist*
201154 citationsauthor #4
Drug Discovery Opportunities and Challenges at G Protein Coupled Receptors for Long Chain Free Fatty Acids
201150 citationsauthor #1
Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1
201128 citationsauthor #5
The Evolving Pharmacology of GPCRs
20104 citationsauthor #2
RESEARCH PAPER Quantitative analysis of neuropeptide Y receptor association with b-arrestin2 measured by bimolecular fluorescence complementation
20100 citationsauthor #4
Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networks
201054 citationsauthor #3
Characterization of G-Protein Coupled Receptor Kinase Interaction with the Neurokinin-1 Receptor Using Bioluminescence Resonance Energy Transfer
200827 citationsauthor #2
Characterization of G-Protein Coupled Receptor Kinase Interaction with the NK-1 Receptor Using BRET
20071 citationsauthor #2
Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor.
200796 citationsauthor #1
Y4 Receptors Mediate the Inhibitory Responses of Pancreatic Polypeptide in Human and Mouse Colon Mucosa
200643 citationsauthor #2
Role of the C Terminus in Neuropeptide Y Y Receptor Desensitization and Internalization
200545 citationsauthor #1
Common Structural Basis for Constitutive Activity of the Ghrelin Receptor Family*
2004344 citationsauthor #2
NPY Receptor Subtypes and Their Signal Transduction
200428 citationsauthor #1
Neuropeptide Y and Related Peptides
200459 citationsauthor #1
Role of the neuropeptide Y Y1 receptor C terminus in promoting agonist-induced desensitisation
20040 citationsauthor #1
Control of signalling efficacy by palmitoylation of the rat Y1 receptor
200321 citationsauthor #1
Constitutive neuropeptide Y Y4 receptor expression in human colonic adenocarcinoma cell lines
200121 citationsauthor #4
PYY preference is a common characteristic of neuropeptide Y receptors expressed in human, rat, and mouse gastrointestinal epithelia.
200012 citationsauthor #1
Functional somatostatin (SRIF) responses in human adenocarcinoma cells transfected with human or rat sst(2) receptors
20000 citationsauthor #1
Modulation of chloride, potassium and bicarbonate transport by muscarinic receptors in a human adenocarcinoma cell line
19997 citationsauthor #1
Inhibition of cyclic AMP-dependent chloride secretion by PP receptors and α2-adrenoceptors in a human colonic epithelial cell line
199711 citationsauthor #1
The functional investigation of a human adenocarcinoma cell line, stably transfected with the neuropeptide Y Y1 receptor
199611 citationsauthor #1
XXVIIth Annual Meeting of the European Chemoreception Research
year unknown0 citationsauthor #24

TIMELINE

1996 11 citations

1997 11 citations

1999 7 citations

2000 12 citations

2001 21 citations

2003 21 citations

2004 431 citations

2005 45 citations

2006 43 citations

2007 97 citations

2008 27 citations

2010 58 citations

2011 166 citations

2012 233 citations

2013 0 citations

2014 24 citations

2015 73 citations

2016 120 citations

2017 180 citations

2018 18 citations

2019 24 citations

2020 80 citations

2021 458 citations

2022 59 citations

2023 12 citations

2024 5 citations

Unknown 0 citations

N. Holliday

PROFILE

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