P. Downton

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Aliases
P Downton, Polly J. Downton, Polly Downton
Publication record
22 papers · 876 citations · H-index 11

PAPERS

Colonic inflammation modulates the intestinal circadian landscape
20251 citationsauthor #2
Meal timing is a critical factor for maintenance of gut homeostasis around the clock
20250 citationsauthor #2
Genome editing of a low-penetrance albinism-associated variant in TYR in patient-derived pluripotent stem cells
20251 citationsauthor #1
Fibroblast-like synoviocytes orchestrate daily rhythmic inflammation in arthritis
20245 citationsauthor #1
Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression
202318 citationsauthor #1
Identification of diurnal rhythmic blood markers in bronchial asthma
20236 citationsauthor #6
Consequences of collagen induced inflammatory arthritis on circadian regulation of the gut microbiome
20228 citationsauthor #2
Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism
202221 citationsauthor #1
L1 Blood immune cells clock mechanism is altered in asthma, with a time-of-day dependent response to steroids in vitro
20212 citationsauthor #2
Author response: Adipocyte NR1D1 dictates adipose tissue expansion during obesity
20210 citationsauthor #7
Adipocyte NR1D1 dictates adipose tissue expansion during obesity
202144 citationsauthor #7
The histone methyltransferase Ezh2 restrains macrophage inflammatory responses
202119 citationsauthor #4
Ezh2 restrains macrophage inflammatory responses, and is critical for neutrophil migration in response to pulmonary infection
20200 citationsauthor #4
Adipocyte REVERBα dictates adipose tissue expansion during obesity
20200 citationsauthor #6
Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism
202043 citationsauthor #4
Circadian rhythms in adaptive immunity
201966 citationsauthor #1
Temperature regulates NF-κB dynamics and function through timing of A20 transcription
201856 citationsauthor #8
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation
201847 citationsauthor #5
Asymmetry between Activation and Deactivation during a Transcriptional Pulse
201713 citationsauthor #4
Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states
201678 citationsauthor #3
The cis-regulatory module interactome of vertebrate myoD1
20120 citationsauthor #1
Signatures of Adaptation to Obligate Biotrophy in the Hyaloperonospora arabidopsidis Genome
2010452 citationsauthor #18

TIMELINE

2010 452 citations

2012 0 citations

2016 78 citations

2017 13 citations

2018 103 citations

2019 66 citations

2020 43 citations

2021 65 citations

2022 29 citations

2023 24 citations

2024 5 citations

2025 2 citations

P. Downton

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