Jeffrey J. Lochhead

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Aliases
Jeff Lochhead, Jeffrey J Lochhead, Jeffrey James Lochhead, Jeffrey Lochhead
Publication record
32 papers · 3,153 citations · H-index 18

PAPERS

The role of oxidative stress in blood-brain barrier disruption during ischemic stroke: Antioxidants in clinical trials.
202437 citationsauthor #1
Abstract TP209: Role Of Endoglin In The Regulation Of Organic Anion Transporting Polypeptide 1a4 At The Blood-brain Barrier: Relevance To The Treatment Of Ischemic Stroke
20230 citationsauthor #4
High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke
20238 citationsauthor #1
Abstract WP244: Localization And Expression Of Transporters For Cationic Drugs At The Blood-brain Barrier: Relevance To The Pharmacotherapy Of Ischemic Stroke
20230 citationsauthor #4
Abstract TP205: Organic Anion Transporting Polypeptides: Endogenous Blood-brain Barrier Transporters That Are Required For Statins To Exert Neuroprotective Effects In Ischemic Stroke
20230 citationsauthor #4
Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke
202312 citationsauthor #5
Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor-β/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins)
202212 citationsauthor #4
High-Dose Acetaminophen Alters the Integrity of the Blood–Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats
20226 citationsauthor #9
β_IV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling
20220 citationsauthor #8
βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling
202213 citationsauthor #8
Abstract TP121: Organic Anion Transporting Polypeptide (Oatp)-Mediated Transport is Required for Statin-Induced Neuroprotection: A Role for Blood-Brain Barrier Transporters in Stroke Treatment
20200 citationsauthor #2
Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders
2020318 citationsauthor #1
Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration
201978 citationsauthor #1
Distribution of insulin in trigeminal nerve and brain after intranasal administration
2019113 citationsauthor #1
Intranasal delivery of antibodies bypasses the blood‐brain barrier and results in significantly higher central nervous system levels than systemic administration
20181 citationsauthor #3
Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose‐response, and mechanisms of delivery
201883 citationsauthor #2
Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System
201770 citationsauthor #1
Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery
201649 citationsauthor #3
Rapid Transport within Cerebral Perivascular Spaces Underlies Widespread Tracer Distribution in the Brain after Intranasal Administration
2015231 citationsauthor #1
Intranasal Drug Delivery to the Brain
201432 citationsauthor #1
Tempol modulates changes in xenobiotic permeability and occludin oligomeric assemblies at the blood-brain barrier during inflammatory pain.
201243 citationsauthor #1
Intranasal delivery of biologics to the central nervous system.
20121,050 citationsauthor #1
OXIDATIVE STRESS ALTERS BLOOD-BRAIN BARRIER INTEGRITY
20110 citationsauthor #1
Oxidative Stress Increases Blood–Brain Barrier Permeability and Induces Alterations in Occludin during Hypoxia–Reoxygenation
2010329 citationsauthor #1
Occludin oligomeric assemblies at tight junctions of the blood–brain barrier are altered by hypoxia and reoxygenation stress
200993 citationsauthor #7
Cholesterol, copper and Abeta in controls, MCI, AD and the AD cholesterol-lowering treatment trial (ADCLT).
200539 citationsauthor #9
Cholesterol, copper and statin therapy in Alzheimer's disease
20050 citationsauthor #14
Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD.
200573 citationsauthor #10
Water quality and cholesterol-induced pathology: differential effects of the M-1 muscarinic receptor agonist Af267B on accumulation of Alzheimer-Like amyloid _ In rabbit brain
20051 citationsauthor #2
Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.
2005416 citationsauthor #9
Cholesterol modifies classical conditioning of the rabbit (Oryctolagus cuniculus) nictitating membrane response.
200323 citationsauthor #3
Water quality has a pronounced effect on cholesterol-induced accumulation of Alzheimer amyloid β (Aβ) in rabbit brain
200231 citationsauthor #2

TIMELINE

2002 31 citations

2003 23 citations

2005 529 citations

2009 93 citations

2010 329 citations

2011 0 citations

2012 1,093 citations

2014 32 citations

2015 231 citations

2016 49 citations

2017 70 citations

2018 84 citations

2019 191 citations

2020 318 citations

2022 31 citations

2023 20 citations

2024 37 citations

Jeffrey J. Lochhead

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