N. Kiyosawa

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Aliases
N. Kiyosawa, Naoki Kiyosawa
Publication record
61 papers · 1,094 citations · H-index 21

PAPERS

Activation of Naturally Occurring Lecithin:Cholesterol Acyltransferase Mutants by a Novel Activator Compound
202013 citationsauthor #9
Exploratory Analysis of Circulating miRNA Signatures in Atrial Fibrillation Patients Determining Potential Biomarkers to Support Decision-Making in Anticoagulation and Catheter Ablation
202023 citationsauthor #1
Activation of naturally occurring LCAT mutants by a novel activator compound
20202 citationsauthor #10
Circulating miRNA Signature as a Potential Biomarker for the Prediction of Analgesic Efficacy of Hydromorphone
201920 citationsauthor #1
Identification of Circulating miRNAs Differentially Regulated by Opioid Treatment
201746 citationsauthor #2
Comprehensive Evaluation of (+)-Usnic Acid–induced Cardiotoxicity in Rats by Sequential Cross-omics Analysis
20175 citationsauthor #4
Data-intensive drug development in the information age: applications of Systems Biology/Pharmacology/Toxicology.
20164 citationsauthor #1
Pharmacokinetics and circulating Microrna profiles of extended release Hydromorphone in healthy subjects
20150 citationsauthor #2
(+)-Usnic Acid-induced Myocardial Toxicity in Rats
201514 citationsauthor #4
of atrophyprofile of a myotube starvation model
20140 citationsauthor #10
PPARα-mediated responses in human adult liver stem cells: In vivo/in vitro and cross-species comparisons.
201311 citationsauthor #2
Developing a practical toxicogenomics data analysis system utilizing open-source software.
20133 citationsauthor #2
Hepatic transcriptome and proteome responses against diethyl maleate-induced glutathione depletion in the rat
201120 citationsauthor #2
Cerivastatin induces type-I fiber-, not type-II fiber-, predominant muscular toxicity in the young male F344 rats.
201128 citationsauthor #4
Toxicogenomic investigation on rat testicular toxicity elicited by 1,3-dinitrobenzene.
20119 citationsauthor #3
Gene set-level network analysis using a toxicogenomics database.
201014 citationsauthor #1
Ethylene Glycol Monomethyl Ether–Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family
201044 citationsauthor #5
Practical Application of Toxicogenomics for Profiling Toxicant-Induced Biological Perturbations
201030 citationsauthor #1
glutathione S-transferase Mu 1 gene
20102 citationsauthor #3
Methemoglobinemia Induced by 1,2-Dichloro-4-nitrobenzene in Mice with a Disrupted Glutathione S-Transferase Mu 1 Gene
201021 citationsauthor #3
Scoring multiple toxicological endpoints using a toxicogenomic database.
200914 citationsauthor #1
Toxicogenomic Biomarkers for Liver Toxicity
200927 citationsauthor #1
Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy.
200929 citationsauthor #3
Species-specific differences in coumarin-induced hepatotoxicity as an example toxicogenomics-based approach to assessing risk of toxicity to humans
200844 citationsauthor #2
A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats.
2008111 citationsauthor #4
o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver.
200836 citationsauthor #1
Toxicokintic and toxicodynamic analysis of clofibrate based on free drug concentrations in nagase analbuminemia rats (NAR).
20087 citationsauthor #5
Gene expression profiling of methapyrilene-induced hepatotoxicity in rat.
200830 citationsauthor #2
Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT
200843 citationsauthor #1
Erratum: o,p′-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver (Toxicological Sciences (2008) vol. 101 (350-363) 10.1093/toxsci/kfm275)
20080 citationsauthor #1
Resistance to the skeletal muscle injury expressed by repeated treatment with compound A that has HMG-CoA reductase inhibitory activity.
20071 citationsauthor #2
Characterization of resistance to bromobenzene-induced hepatotoxicity by microarray.
200719 citationsauthor #2
Identification of glutathione depletion-responsive genes using phorone-treated rat liver.
200732 citationsauthor #1
Gene expression profiling of rat liver treated with serum triglyceride-decreasing compounds.
200714 citationsauthor #2
Influence of Kupffer cell inactivation on cycloheximide-induced hepatic injury.
200718 citationsauthor #2
A toxicogenomics approach for risk assessment of glutathione depletion and oxidative stress-induced nongenotoxic hepatocarcinogenesis in the rat liver
20060 citationsauthor #2
Molecular mechanism investigation of cycloheximide-induced hepatocyte apoptosis in rat livers by morphological and microarray analysis.
200643 citationsauthor #2
Toxicoproteomic investigation of the molecular mechanisms of cycloheximide-induced hepatocellular apoptosis in rat liver.
200613 citationsauthor #3
Utilization of a one-dimensional score for surveying chemical-induced changes in expression levels of multiple biomarker gene sets using a large-scale toxicogenomics database.
200627 citationsauthor #1
Utilization of a toxicogenomic biomarker for evaluation of chemical-induced glutathione deficiency in rat livers across the GeneChip data of different generations.
20063 citationsauthor #1
Gene expression analysis in rat livers and immune organs treated with isoniazid, phenytoin, hydralazine hydrochloride or chlorpromazine(Proceedings of the 32nd Annual Meeting)
20050 citationsauthor #2
Microarray analysis on CYPs expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile and phenobarbital.
200517 citationsauthor #3
Microarray analysis of T-2 toxin-induced liver, placenta and fetal liver lesions in pregnant rats.
200567 citationsauthor #2
Gene expression analysis on rat livers treated with L-buthionine (S, R)-sulfoximine : investigation of data compatibility between RG U34A and RAE 230A GeneChips(Toxicogenomics, Toxicoproteomics, Proceedings of the 32nd Annual Meeting)
20050 citationsauthor #1
Relationship between hepatocellular apoptosis and Kupffer cell activation in the livers of rats treated with cycloheximide(Proceedings of the 32nd Annual Meeting)
20050 citationsauthor #2
Induction of Cytochrome P450 isozymes by phenobarbital in pregnant rat and fetal livers and placenta(Drug metabolism, Proceedings of the 32nd Annual Meeting)
20050 citationsauthor #2
Toxicogenomics : New approach for drug development
20050 citationsauthor #1
Microarray analysis on Phase II drug metabolizing enzymes expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile or phenobarbital.
200517 citationsauthor #3
Molecular mechanism investigation of phenobarbital-induced serum cholesterol elevation in rat livers by microarray analysis
200438 citationsauthor #1
Evaluation of glutathione deficiency in rat livers by microarray analysis.
200425 citationsauthor #1
Gene expression profiles in pregnant rats treated with T-2 toxin.
200427 citationsauthor #2
Morphological and microarray analysis of T-2 toxin-induced rat fetal brain lesion.
200472 citationsauthor #2
Effect of serum cholesterol on the mRNA content of amyloid precursor protein in rat livers.
20042 citationsauthor #1
P6-47 Relationship between hepatic glutathione content and gene expression profile in F344 male rats treated with L-Buthionine(S,R)-sulfoximine(TOXICOGENOMICS)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
20040 citationsauthor #2
P7-41 Skeletal muscle injury caused by compound A completely recovers in spite of further treatment?(GENERAL TOXICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
20040 citationsauthor #2
Gene expression analysis in the liver of rats treated with phenobarbital and 3-methylsholanthrene using DNA microarray (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
20030 citationsauthor #1
Involvement of Drug Transporters in the Acquired Resistance to Bromobenzene-induced Hepatotoxicity (LIVER/DIGESTIVE SYSTEM) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
20030 citationsauthor #2
Phylogenetic tree facilitates the understanding of gene expression data on drug metabolizing enzymes obtained by microarray analysis.
200310 citationsauthor #1
Gene Expression Profiles in the Liver, Placenta and Fetal Liver in Pregnant Rats Treated with T-2 Toxin (TOXICOGENOMICS AND TOXICOPROTEOMICS) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
20030 citationsauthor #2
SUPPRESSION OF PPAR ALPHA SIGNAL CAUSED BY POLYCYCLIC AROMATIC HYDROCARBONS.(GENERAL SESSION BY POSTER PRESENTATION)(MOLECULAR TOXICITY & TOXICOGENOMICS)
20020 citationsauthor #2
Synthesis of Fibronectin-related Peptides : the RGD Peptides and the Third Domain Peptides
20010 citationsauthor #2

TIMELINE

2001 0 citations

2002 0 citations

2003 10 citations

2004 164 citations

2005 101 citations

2006 86 citations

2007 84 citations

2008 271 citations

2009 70 citations

2010 111 citations

2011 57 citations

2013 14 citations

2014 0 citations

2015 14 citations

2016 4 citations

2017 51 citations

2019 20 citations

2020 38 citations

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