D. Burkhart

PROFILE

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Aliases
D J Burkhart, David J Burkhart, David J. Burkhart, David Burkhart
Publication record
37 papers · 519 citations · H-index 13

PAPERS

Covalent conjugation of a TLR7/8 agonist to recombinant influenza A virus hemagglutinin provides enhanced immunogenicity and protection against disease from a drifted strain 9291
20250 citationsauthor #5
Adjuvanted Vaccine Induces Functional Antibodies against Pseudomonas aeruginosa Filamentous Bacteriophages
20241 citationsauthor #7
Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses
20246 citationsauthor #10
Intranasal administration of a synthetic TLR4 agonist INI-2004 significantly reduces allergy symptoms following therapeutic administration in a murine model of allergic sensitization
20243 citationsauthor #9
Promotion of Th17 Polarized Immunity via Co-Delivery of Mincle Agonist and Tuberculosis Antigen Using Silica Nanoparticles.
20244 citationsauthor #12
TLR Agonist INI-4001 Improves Efficacy of Heroin Vaccine Intended for Clinical Treatment of Opioid Use Disorder
20230 citationsauthor #3
Co-Delivery of Novel Synthetic TLR4 and TLR7/8 Ligands Adsorbed to Aluminum Salts Promotes Th1-Mediated Immunity against Poorly Immunogenic SARS-CoV-2 RBD
20236 citationsauthor #8
Deciphering immunological mechanisms underlying the efficacy of nanoparticle-based vaccines against opioid use disorder (OUD)
20231 citationsauthor #6
Deciphering immunological mechanisms underlying the efficacy of nanoparticle-based vaccines and novel adjuvants against Opioid Use Disorder (OUD)
20230 citationsauthor #6
Self-Adjuvanting TLR7/8 Agonist and Fentanyl Hapten Co-Conjugate Achieves Enhanced Protection against Fentanyl Challenge
202311 citationsauthor #9
A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice
202313 citationsauthor #7
A novel, synthetic TLR7/8 agonist demonstrates monotherapy efficacy and synergy with anti-PD-1 in syngeneic mouse tumor models
20220 citationsauthor #8
Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination
202217 citationsauthor #15
Using Dual Toll-like Receptor Agonism to Drive Th1-Biased Response in a Squalene- and α-Tocopherol-Containing Emulsion for a More Effective SARS-CoV-2 Vaccine
202214 citationsauthor #9
1168 A novel immunostimulatory TLR7/8 agonist is curative as a monotherapy in lewis lung carcinoma and synergizes with anti-PD-1 in B16F10 and MC38 tumor models
20220 citationsauthor #9
Cationic liposomes containing a TLR4 agonist promote the efficient development of cellular immunity against SARS-CoV-2 Spike protein in a subunit vaccine.
20222 citationsauthor #6
Adjuvanted multivalent vaccine targeting clinically relevant Pf bacteriophage creates cross-reactive antibodies
20220 citationsauthor #6
Combinations of alum and synthetic toll-like receptor agonists as adjuvants for CoVID-19 vaccines
20210 citationsauthor #6
A tractable covalent linker strategy for the production of immunogenic antigen-TLR7/8L bioconjugates
20216 citationsauthor #7
Co-delivery of antigens with TLR7/8 agonists leads to an improved Th1-mediated immune response to subunit vaccines.
20212 citationsauthor #5
A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity
202024 citationsauthor #11
Influenza vaccines using liposomal formulations of toll-like receptor (TLR) 7/8 and 4 agonists as adjuvants
20204 citationsauthor #6
Adjuvanted bacteriophage vaccine targeting Pseudomonas aeruginosa
20201 citationsauthor #7
Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice
202050 citationsauthor #7
Codelivery of antigens with TLR7/8 agonists leads to an improved immune response to influenza vaccination
20200 citationsauthor #5
Co-Adsorption of Synthetic Mincle Agonists and Antigen to Silica Nanoparticles for Enhanced Vaccine Activity: A Formulation Approach to Co-Delivery.
202012 citationsauthor #7
Species-Specific Structural Requirements of Alpha-Branched Trehalose Diester Mincle Agonists
201921 citationsauthor #8
Co-encapsulation of synthetic lipidated TLR4 and TLR7/8 agonists in the liposomal bilayer results in a rapid, synergistic enhancement of vaccine-mediated humoral immunity.
201938 citationsauthor #7
Investigation of novel TLR7/8 ligands in combination with TLR4 ligands as adjuvants to drive cell mediated anti-influenza immunity
20182 citationsauthor #6
Vaccine adjuvants: Softness makes it better.
201815 citationsauthor #2
Age-specific TLR7/8 adjuvant formulation overcomes hyporesponsiveness to neonatal acellular pertussis vaccination in a mouse model
20182 citationsauthor #7
Liposomal vaccine formulations as prophylactic agents: design considerations for modern vaccines
201786 citationsauthor #2
Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization
201742 citationsauthor #11
PEG modified liposomes containing CRX-601 adjuvant in combination with methylglycol chitosan enhance the murine sublingual immune response to influenza vaccination.
201665 citationsauthor #5
Methylglycol chitosan and a synthetic TLR4 agonist enhance immune responses to influenza vaccine administered sublingually.
201527 citationsauthor #5
Methods to monitor monocytes-mediated amyloid-beta uptake and phagocytosis in the context of adjuvanted immunotherapies.
201524 citationsauthor #13
Doxorubicin-formaldehyde conjugates targeting αvβ3 integrin
200422 citationsauthor #1

TIMELINE

2004 22 citations

2015 51 citations

2016 65 citations

2017 128 citations

2018 19 citations

2019 59 citations

2020 91 citations

2021 8 citations

2022 33 citations

2023 31 citations

2024 14 citations

2025 0 citations

D. Burkhart

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PAPERS

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