A. Miranker

PROFILE

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Aliases
A. Miranker, Andrew David Miranker, A D Miranker, Andrew D. Miranker, Andrew D Miranker, Andrew Miranker, A Miranker
Publication record
95 papers · 6,428 citations · H-index 40

PAPERS

Assessing and mitigating privacy risk of sparse, noisy genotypes by local 3 alignment to haplotype databases 4
20220 citationsauthor #3
Assessing and mitigating privacy risk of sparse, noisy genotypes by local alignment to haplotype databases
20212 citationsauthor #3
Data Sanitization to Reduce Private Information Leakage from Functional Genomics.
202033 citationsauthor #8
α-Synuclein Binds Extracellular Complex N-Linked Glycans
20190 citationsauthor #3
STEM Climate survey developed through student–faculty collaboration
20199 citationsauthor #12
Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid
20180 citationsauthor #4
Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands.
201814 citationsauthor #4
Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid
201846 citationsauthor #4
Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein
201847 citationsauthor #3
Toxic and Non-Toxic Forms of Membrane Poration are Mediated by Structurally Distinct States of Islet Amyloid Polypeptide
20170 citationsauthor #4
Foldamer-mediated manipulation of a pre-amyloid toxin
201650 citationsauthor #6
Structurally distinct oligomers of islet amyloid polypeptide mediate toxic and non-toxic membrane poration
20160 citationsauthor #4
Foldamer scaffolds suggest distinct structures are associated with alternative gains-of-function in a preamyloid toxin.
201614 citationsauthor #3
Influence of the Human and Rat Islet Amyloid Polypeptides on Structure of Phospholipid Bilayers: Neutron Reflectometry and Fluorescence Microscopy Studies.
20168 citationsauthor #4
Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity.
201510 citationsauthor #4
A solenoid design for assessing determinants of parallel β-sheet registration.
20150 citationsauthor #2
A Role for Unstructured Residues in the Induction of Membrane Poration by Pre-Amyloid Assemblies of Islet Amyloid Polypeptide
20150 citationsauthor #3
Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics.
201550 citationsauthor #10
Amphiphilic oligoamide α-helix peptidomimetics inhibit islet amyloid polypeptide aggregation
201526 citationsauthor #7
Recent Insight in Islet Amyloid Polypeptide Morphology, Structure, Membrane Interaction, and Toxicity in Type 2 Diabetes
20159 citationsauthor #3
Mapping Protein Conformational Landscapes under Strongly Native Conditions with Hydrogen Exchange Mass Spectrometry.
20158 citationsauthor #5
Foldamer-Based Enantioselective Targeting of Islet Amyloid Polypeptide
20150 citationsauthor #3
Peptide Amyloid Surface Display
20148 citationsauthor #4
Folded small molecule manipulation of islet amyloid polypeptide.
201423 citationsauthor #4
Surface-Catalyzed Nucleation of Amyloidogenic Peptides by Peptide-Specific Templates
20140 citationsauthor #2
Fiber-dependent and -independent toxicity of islet amyloid polypeptide.
201430 citationsauthor #2
Small molecule screening in context: Lipid‐catalyzed amyloid formation
201414 citationsauthor #3
Screening and Design of New Modulators of IAPP Membrane-Binding and Toxicity
20130 citationsauthor #5
Membrane Geometry Alters the Interaction between Islet Amyloid Polypeptide and Lipid Bilayers
20130 citationsauthor #2
A physical chemical approach to understanding cellular dysfunction in type II diabetes
20130 citationsauthor #1
Inhibition and Mechanism of Islet Amyloid Polypeptide Toxicity
20131 citationsauthor #5
A foldamer approach to targeting membrane bound helical states of islet amyloid polypeptide.
201339 citationsauthor #2
Common mechanism unites membrane poration by amyloid and antimicrobial peptides
2013173 citationsauthor #2
A common landscape for membrane‐active peptides
201382 citationsauthor #3
Design and Characterization of Peptide Modulators of IAPP-Membrane Binding
20130 citationsauthor #3
Designing Self Assembling Beta Helices
20130 citationsauthor #4
Targeting Protein Misfolding(Islet Amyloid Polypeptide) using Helical Mimetics
20131 citationsauthor #3
Concentration‐dependent transitions govern the subcellular localization of islet amyloid polypeptide
201276 citationsauthor #2
A membrane-bound antiparallel dimer of rat islet amyloid polypeptide.
201140 citationsauthor #2
Protein aggregation: p53 succumbs to peer pressure.
20117 citationsauthor #2
Evolution of Membrane Leakage by Pre-Amyloidogenic Oligomers of Islet Amyloid Polypeptide
20110 citationsauthor #2
Single Molecule Studies of Unstructured Protein Function and Dynamics
20110 citationsauthor #3
Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity
2011131 citationsauthor #3
Selenium NMR Spectroscopy as Versatile Probe of Selenoproteins
20110 citationsauthor #7
Single-Molecule Enzymology: Studies on Glutathione-S-Transferases
20110 citationsauthor #3
Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation.
2010112 citationsauthor #5
Small Molecule Inhibitors of Islet Amyloid Polypeptide Fibrillogenesis and Cytotoxicity
20100 citationsauthor #3
Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs.
201050 citationsauthor #4
Pre-Amyloid States of Islet Amyloid Polypeptide Examined by Single-Particle Fluorescence
20100 citationsauthor #2
Protein-induced photophysical changes to the amyloid indicator dye thioflavin T
2010322 citationsauthor #5
Delineating the conformational elements responsible for Cu(2+)-induced oligomerization of beta-2 microglobulin.
200920 citationsauthor #2
The role of prefibrillar structures in the assembly of a peptide amyloid.
200923 citationsauthor #2
Metal binding sheds light on mechanisms of amyloid assembly
200937 citationsauthor #2
A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes.
200986 citationsauthor #5
The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes.
2009227 citationsauthor #2
Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide.
2009173 citationsauthor #3
Single Particle Analysis of Liposome Leakage Induced by Islet Amyloid Polypeptide
20090 citationsauthor #2
A regulatable switch mediates self-association in an immunoglobulin fold
200896 citationsauthor #4
Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide.
200855 citationsauthor #3
Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry
200849 citationsauthor #3
Interaction of membrane‐bound islet amyloid polypeptide with soluble and crystalline insulin
200883 citationsauthor #3
Fiber-dependent amyloid formation as catalysis of an existing reaction pathway
2007205 citationsauthor #2
Backbone 1H, 13C, and 15N and CB Assignments for Rat Islet Amyloid Polypeptide
20070 citationsauthor #2
Formation of a stable oligomer of beta-2 microglobulin requires only transient encounter with Cu(II).
200740 citationsauthor #2
Direct detection of transient α‐helical states in islet amyloid polypeptide
2007205 citationsauthor #2
Direct detection of transient alpha-helical states in islet amyloid polypeptide.
200746 citationsauthor #2
Scope and utility of hydrogen exchange as a tool for mapping landscapes
200716 citationsauthor #2
A native to amyloidogenic transition regulated by a backbone trigger
2006189 citationsauthor #3
Conserved and cooperative assembly of membrane-bound alpha-helical states of islet amyloid polypeptide.
2006294 citationsauthor #3
From chance to frequent encounters: origins of beta2-microglobulin fibrillogenesis.
200548 citationsauthor #2
Contribution of the intrinsic disulfide to the assembly mechanism of islet amyloid
200571 citationsauthor #2
Quantitative measurement of fibrillogenesis by mass spectrometry.
20051 citationsauthor #1
Structural biology: Fibres hinge on swapped domains
20057 citationsauthor #1
Unzipping the mysteries of amyloid fiber formation.
200419 citationsauthor #1
Phospholipid catalysis of diabetic amyloid assembly.
2004349 citationsauthor #2
The mechanism of insulin action on islet amyloid polypeptide fiber formation.
2004120 citationsauthor #2
Oligomeric assembly of native-like precursors precedes amyloid formation by beta-2 microglobulin.
2004118 citationsauthor #4
Formation of a copper specific binding site in non-native states of beta-2-microglobulin.
2002102 citationsauthor #5
Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of fibrillogenesis.
2002322 citationsauthor #2
Kidney dialysis-associated amyloidosis: a molecular role for copper in fiber formation.
2001147 citationsauthor #4
Islet amyloid polypeptide: identification of long-range contacts and local order on the fibrillogenesis pathway.
2001118 citationsauthor #2
Mass spectrometry of proteins of known mass.
20007 citationsauthor #1
Protein complexes and analysis of their assembly by mass spectrometry.
200026 citationsauthor #1
Global unfolding of a substrate protein by the Hsp100 chaperone ClpA
1999425 citationsauthor #3
Conformational dynamics and protein unfolding in lysozyme amyloidosis
19990 citationsauthor #2
Characterization of collapsed states in the early stages of the refolding of hen lysozyme.
199824 citationsauthor #2
Hydrogen exchange properties of proteins in native and denatured states monitored by mass spectrometry and NMR
199787 citationsauthor #5
Isotope-labeling strategy for the assignment of protein fragments generated for mass spectrometry
199613 citationsauthor #1
Collapse and cooperativity in protein folding.
1996113 citationsauthor #1
Investigation of protein folding by mass spectrometry
1996152 citationsauthor #1
Cooperative Elements in Protein Folding Monitored by Electrospray Ionization Mass Spectrometry
199535 citationsauthor #3
An automated method for dynamic ligand design
199585 citationsauthor #1
Functionality maps of binding sites: A multiple copy simultaneous search method
1991503 citationsauthor #1
Demonstration by NMR of folding domains in lysozyme
1991222 citationsauthor #1
Numerical Methods for Stiff Equations
198036 citationsauthor #2

TIMELINE

1980 36 citations

1991 725 citations

1995 120 citations

1996 278 citations

1997 87 citations

1998 24 citations

1999 425 citations

2000 33 citations

2001 265 citations

2002 424 citations

2004 606 citations

2005 127 citations

2006 483 citations

2007 512 citations

2008 283 citations

2009 566 citations

2010 484 citations

2011 178 citations

2012 76 citations

2013 296 citations

2014 75 citations

2015 103 citations

2016 72 citations

2017 0 citations

2018 107 citations

2019 9 citations

2020 33 citations

2021 2 citations

2022 0 citations

A. Miranker

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