P. Sarkar

PROFILE

Homepage
No homepage is listed.
ORCID
No ORCID is listed.
Affiliations
No affiliations are listed.
Aliases
Partha S. Sarkar, P S Sarkar, Parthas S Sarkar, Partha S Sarkar, Partha Sarkar
Publication record
49 papers · 2,806 citations · H-index 33

PAPERS

Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons
20240 citationsauthor #21
Correction: The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
20240 citationsauthor #16
The future of cancer treatment: combining radiotherapy with immunotherapy
202423 citationsauthor #12
Polyglutamine Expansion in Huntingtin and Mechanism of DNA Damage Repair Defects in Huntington’s Disease
202222 citationsauthor #6
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases
202111 citationsauthor #10
Huntingtin Maintains Mitochondrial Genome Integrity and Function
20210 citationsauthor #20
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s disease
202137 citationsauthor #27
Deficiency in classical nonhomologous end-joining–mediated repair of transcribed genes is linked to SCA3 pathogenesis
202031 citationsauthor #12
Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription
2019108 citationsauthor #15
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences
201870 citationsauthor #7
Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes
2016150 citationsauthor #7
Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10
201642 citationsauthor #4
Glucocorticoids increase skeletal muscle NF‐κB inducing kinase (NIK): links to muscle atrophy
201643 citationsauthor #4
The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
201593 citationsauthor #16
Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3
201583 citationsauthor #14
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation* ♦
201592 citationsauthor #12
Structure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity.
201458 citationsauthor #7
Ethanol Suppresses PGC-1α Expression by Interfering with the cAMP-CREB Pathway in Neuronal Cells
201429 citationsauthor #8
Paradoxical effects of repeat interruptions on spinocerebellar ataxia type 10 expansions and repeat instability
201335 citationsauthor #5
Mutant Ataxin‐3 inhibits 3’ phosphatase activity of human polynucleotide kinase 3′‐phosphatase (PNKP)
20130 citationsauthor #8
Purkinje cell loss is the major brain pathology of spinocerebellar ataxia type 10
201331 citationsauthor #4
Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
20131 citationsauthor #7
Klotho Ameliorates Chemically Induced Endoplasmic Reticulum (ER) Stress Signaling
201345 citationsauthor #3
Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2.
201252 citationsauthor #6
Transgenic mice with SCA10 pentanucleotide repeats show motor phenotype and susceptibility to seizure: A toxic RNA gain‐of‐function model
201248 citationsauthor #5
Myotonic dystrophy types 1 and 2.
201178 citationsauthor #2
Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast
201149 citationsauthor #7
Klotho Depletion Contributes to Increased Inflammation in Kidney of the db/db Mouse Model of Diabetes via RelA (Serine)536 Phosphorylation
2011233 citationsauthor #5
RNA Foci, CUGBP1, and ZNF9 are the primary targets of the mutant CUG and CCUG repeats expanded in myotonic dystrophies type 1 and type 2.
201138 citationsauthor #5
The role of human DNA glycosylase NEIL 2 and the single-strand break repair protein polynucleotide kinase 3 '-phosphatase in maintenance of the mitochondrial genome
20111 citationsauthor #11
Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome*
201188 citationsauthor #11
Inactivation of hnRNP K by Expanded Intronic AUUCU Repeat Induces Apoptosis Via Translocation of PKCδ to Mitochondria in Spinocerebellar Ataxia 10
2010112 citationsauthor #12
Expansion of CUG RNA repeats causes stress and inhibition of translation in myotonic dystrophy 1 (DM1) cells
201099 citationsauthor #8
Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells*
2010138 citationsauthor #8
Expression of RNA CCUG repeats dysregulates translation and degradation of proteins in myotonic dystrophy 2 patients.
200979 citationsauthor #8
Reduction of the Rate of Protein Translation in Patients with Myotonic Dystrophy 2
200988 citationsauthor #5
Cytoplasmic CUG RNA Foci Are Insufficient to Elicit Key DM1 Features
200852 citationsauthor #3
The role of ataxin 10 in the pathogenesis of spinocerebellar ataxia type 10
200664 citationsauthor #8
In situ hybridization analysis of Dmpk mRNA in adult mouse tissues.
200433 citationsauthor #1
Six5 is required for spermatogenic cell survival and spermiogenesis.
200469 citationsauthor #1
Characterization of Cardiac Conduction System Abnormalities in Mice with Targeted Disruption of Six5 Gene
200249 citationsauthor #5
Overexpression of Smad2 reveals its concerted action with Smad4 in regulating TGF-beta-mediated epidermal homeostasis.
200169 citationsauthor #2
Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts
2000215 citationsauthor #1
CTG repeats show bimodal amplification in E. coli.
199873 citationsauthor #1
Correlation of clinical profile of myotonic dystrophy with CTG repeats in the myotonin protein kinase gene.
199811 citationsauthor #7
Simple repetitive sequences in the genome: Structure and functional significance
199565 citationsauthor #3
A novel approach to design of cis-acting DNA structural element for regulation of gene expression in vivo
19911 citationsauthor #1
Synthetic gene design to investigate the role of cis-acting DNA structural elements in regulation of gene expression in vivo.
19911 citationsauthor #2
Mutant huntingtin impairs PNKP and ATXN 3 , disrupting DNA repair and transcription 1 2 3
year unknown0 citationsauthor #17

TIMELINE

1991 2 citations

1995 65 citations

1998 84 citations

2000 215 citations

2001 69 citations

2002 49 citations

2004 102 citations

2006 64 citations

2008 52 citations

2009 167 citations

2010 349 citations

2011 487 citations

2012 100 citations

2013 112 citations

2014 87 citations

2015 268 citations

2016 235 citations

2018 70 citations

2019 108 citations

2020 31 citations

2021 48 citations

2022 22 citations

2024 23 citations

Unknown 0 citations

P. Sarkar

PROFILE

PAPERS

TIMELINE

COAUTHOR MAP

CONCEPT FOOTPRINT