Leslie I. Grad

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Leslie I Grad, Leslie Ian. Grad
Publication record
24 papers · 2,330 citations · H-index 19

PAPERS

CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1
2019122 citationsauthor #10
Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites
2018128 citationsauthor #6
Intercellular Prion-Like Conversion and Transmission of Cu/Zn Superoxide Dismutase (SOD1) in Cell Culture.
20173 citationsauthor #1
Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS).
2017244 citationsauthor #1
TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion
201687 citationsauthor #2
Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways
201695 citationsauthor #3
Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways
20160 citationsauthor #3
From molecule to molecule and cell to cell: prion-like mechanisms in amyotrophic lateral sclerosis.
201585 citationsauthor #1
Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding
201456 citationsauthor #1
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms
2014417 citationsauthor #1
Prion-like activity of Cu/Zn superoxide dismutase
201466 citationsauthor #1
Aberrant Localization of FUS and TDP43 Is Associated with Misfolding of SOD1 in Amyotrophic Lateral Sclerosis
2012190 citationsauthor #2
Intermolecular transmission of superoxide dismutase 1 misfolding in living cells
2011291 citationsauthor #1
Generalization of the Prion Hypothesis to Other Neurodegenerative Diseases: An Imperfect Fit
201175 citationsauthor #5
P3‐378: Misfolded superoxide dismutase 1 (SOD1) as a novel target for Alzheimer's disease
20102 citationsauthor #1
Isolation and functional analysis of mitochondria from the nematode Caenorhabditis elegans.
200739 citationsauthor #1
Modeling complex I mutations in Caenorhabditis elegans
20060 citationsauthor #2
Riboflavin enhances the assembly of mitochondrial cytochrome c oxidase in C. elegans NADH-ubiquinone oxidoreductase mutants.
200657 citationsauthor #1
Introduction of an additional pathway for lactate oxidation in the treatment of lactic acidosis and mitochondrial dysfunction in Caenorhabditis elegans.
200538 citationsauthor #1
Mitochondrial complex I mutations in Caenorhabditis elegans produce cytochrome c oxidase deficiency, oxidative stress and vitamin-responsive lactic acidosis.
2003129 citationsauthor #1
Mitochondrial Respiratory Chain Deficiency inCaenorhabditis elegans Results in Developmental Arrest and Increased Life Span*
2001151 citationsauthor #3
Locally released retinoic acid repatterns the first branchial arch cartilages in vivo.
200036 citationsauthor #3
Inactivation of the Neurospora crassa mitochondrial outer membrane protein TOM70 by repeat-induced point mutation (RIP) causes defects in mitochondrial protein import and morphology
199926 citationsauthor #1
Functional analysis of the mitochondrial outer membrane protein TOM70 in neurospora crassa
19980 citationsauthor #1

TIMELINE

1998 0 citations

1999 26 citations

2000 36 citations

2001 151 citations

2003 129 citations

2005 38 citations

2006 57 citations

2007 39 citations

2010 2 citations

2011 366 citations

2012 190 citations

2014 539 citations

2015 85 citations

2016 182 citations

2017 247 citations

2018 128 citations

2019 122 citations

Leslie I. Grad

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PAPERS

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