S. Uzunoğlu

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Aliases
S Uzunoglu, S. Uzunoglu, Selim Uzunoglu, Selim Uzunoğlu
Publication record
48 papers · 570 citations · H-index 15

PAPERS

AT-101 acts as anti-proliferative and hormone suppressive agent in mouse pituitary corticotroph tumor cells
20187 citationsauthor #9
Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway
20164 citationsauthor #6
Octreotide in combination with AT-101 induces cytotoxicity and apoptosis through up-regulation of somatostatin receptors 2 and 5 in DU-145 prostate cancer cells
20168 citationsauthor #5
Zoledronic acid increases cytotoxicity by inducing apoptosis in hormone and docetaxel-resistant prostate cancer cell lines
20154 citationsauthor #6
Anti-angiogenic effects of trabectedin (Yondelis; ET-743) on human breast cancer cells
201424 citationsauthor #2
Lack of association between leptin levels and leptin gene polymorphism in obese women
20142 citationsauthor #4
Enhancement of docetaxel efficacy by zoledronic acid pretreatment in docetaxel-resistant prostate cancer cells (PC-3/R and DU-145/R).
20140 citationsauthor #6
97PAT-101 (-/- GOSSYPOL) IN COMBINATION WITH TRASTUZUMAB TRIGGERS APOPTOSIS THROUGH INHIBITING BCL-2, BCL-XL AND MCL-1 PROTEIN LEVELS IN HUMAN HER2-POSITIVE BREAST CANCER CELLS
20130 citationsauthor #6
Preclinical breast cancer biology 97P AT-101 (-/- GOSSYPOL) IN COMBINATION WITH TRASTUZUMAB TRIGGERS APOPTOSIS THROUGH INHIBITING BCL-2, BCL-XL AND MCL-1 PROTEIN LEVELS IN HUMAN HER2-POSITIVE BREAST CANCER CELLS
20130 citationsauthor #6
Combination of AT-101/cisplatin overcomes chemoresistance by inducing apoptosis and modulating epigenetics in human ovarian cancer cells
201345 citationsauthor #5
P05.05 A DIVERSE INDUCTION OF APOPTOSIS BY TRABECTEDIN IN MCF-7 (HER2-/ER+) AND MDA-MB-453 (HER2 + /ER-) BREAST CANCER CELLS
20131 citationsauthor #3
A diverse induction of apoptosis by trabectedin in MCF-7 (HER2-/ER+) and MDA-MB-453 (HER2+/ER-) breast cancer cells.
201342 citationsauthor #3
Poster session 5. Translational research
20130 citationsauthor #22
P05.03 P53 MODULATES TRABECTEDIN MEDIATED CYTOTOXICITY IN GLIOBLASTOMA MULTIFORME CELLS (U-87MG AND T98G)
20130 citationsauthor #3
Trabectedin to induce mitochondrial membrane potential dissipation and reactive oxygen species generation in breast cancer cells.
20130 citationsauthor #5
Paclitaxel in combination with AT-101 induces apoptosis via supressing Bcl-2, bcl-XL, mcl-1 proteins in human breast cancer cells.
20131 citationsauthor #6
Effects of Thymus serpyllum Extract on Cell Proliferation, Apoptosis and Epigenetic Events in Human Breast Cancer Cells
201246 citationsauthor #4
94P Comparison of A Novel, Label-Free, and Real-Time cell Based System (Xcelligence) With a Conventional Viability Assay (Xtt) to Determine the Anti-Proliferative Effect of At-101 in Human Breast Cancer Cells
20120 citationsauthor #9
Pretreatment with AT-101 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of breast cancer cells by inducing death receptors 4 and 5 protein levels
201226 citationsauthor #6
Molecular biology (pre-clinical)
20123 citationsauthor #107
Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone‐refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A
201218 citationsauthor #7
Combination of AT-101/cisplatin overcomes chemoresistance by inducing apoptosis and modulating epigenetics in human ovarian cancer cells
20120 citationsauthor #5
HORMESIS: Antecedent phenomena for adaptation to low doses of toxic agents
20123 citationsauthor #2
98P Octreotide in Combination with Docetaxel Triggers Apoptosis by Inducing Sstr2 and Sstr5 Levels in Human Breast Cancer Cells, Mcf-7 and Mda-Mb-231
20121 citationsauthor #8
Expression profiling of apoptotic proteins in human breast cancer cells treated with AT-101 by protein array technology
20110 citationsauthor #4
Targeting Bcl-2 Protein to Enhance Chemosensitivity of Hormone Refractory Prostate Cancer Cell Line, DU-145 by a Synergistic Combination of Docetaxel and Gossypol
20111 citationsauthor #1
High-Resolution Melting Analysis for Screening of Turkish Germline Mutations in BRCA 1 and BRCA 2
20101 citationsauthor #5
High-Resolution Melting Analysis for Screening of Turkish Germline Mutations in BRCA1 and BRCA2
20101 citationsauthor #5
Synergistic cytotoxic/apoptotic effects of AT-101, a phytochemical with BH3-mimetic property, in combination with paclitaxel in human breast cancer cells.
20100 citationsauthor #7
Comparison of XTT and Alamar blue assays in the assessment of the viability of various human cancer cell lines by AT-101 (−/− gossypol)
201043 citationsauthor #1
Overcoming drug resistance in hormone- and drug-refractory prostate cancer cell line, PC-3 by docetaxel and gossypol combination
201033 citationsauthor #8
Enhancing cytotoxic and apoptotic effect in OVCAR-3 and MDAH-2774 cells with all-trans retinoic acid and zoledronic acid: a paradigm of synergistic molecular targeting treatment for ovarian cancer
201021 citationsauthor #8
Radiosensitization of hormone-refractory prostate cancer cells by gossypol treatment.
201010 citationsauthor #4
Apoptosis-Mediated Cytotoxic Effects of Ibandronic Acid on Hormone- and Drug-Refractory Prostate Cancer Cells and Human Breast Cancer Cells
20103 citationsauthor #8
Regulation of apoptosis-related molecules by synergistic combination of all-trans retinoic acid and zoledronic acid in hormone-refractory prostate cancer cell lines
201021 citationsauthor #5
Enhancement of taxane-induced cytotoxicity and apoptosis by gossypol in human breast cancer cell line MCF-7.
200910 citationsauthor #3
Regulation of growth factors in hormone‐ and drug‐resistant prostate cancer cells by synergistic combination of docetaxel and octreotide
200919 citationsauthor #8
Targeting apoptosis in the hormone‐ and drug‐resistant prostate cancer cell line, DU‐145, by gossypol/zoledronic acid combination
20096 citationsauthor #9
Combined gossypol and zoledronic acid treatment results in synergistic induction of cell death and regulates angiogenic molecules in ovarian cancer cells.
200923 citationsauthor #8
Docetaxel/zoledronic acid combination triggers apoptosis synergistically through downregulating antiapoptotic Bcl‐2 protein level in hormone‐refractory prostate cancer cells
200944 citationsauthor #9
The effect of racemic gossypol and at-101 on angiogenic profile of ovcar-3 cells: a preliminary molecular framework for gossypol enantiomers.
200913 citationsauthor #7
Translational Perspective of Mathematical Models Used in The Assessment of Cellular Synergy in Cytotoxicity Assays
20082 citationsauthor #3
Profiling of angiogenic cytokines produced by hormone- and drug-refractory prostate cancer cell lines, PC-3 and DU-145 before and after treatment with gossypol.
200817 citationsauthor #8
Zoledronic acid effects interleukin-6 expression in hormone-independent prostate cancer cell lines.
20088 citationsauthor #2
Enhancement of docetaxel-induced cytotoxicity and apoptosis by all-trans retinoic acid (ATRA) through downregulation of survivin (BIRC5), MCL-1 and LTbeta-R in hormone- and drug resistant prostate cancer cell line, DU-145
200834 citationsauthor #8
INCIDENCE OF SEVERE GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD) DEFICIENCY IN COUNTRYSIDE VILLAGES OF THE CENTRAL CITY OF MANISA, TURKEY
20062 citationsauthor #2
Evaluation of the association between null genotypes of glutathione-S-transferases and Behcet’s disease
200512 citationsauthor #1
Up-regulation of serine/threonine protein phosphatase type 2A regulatory subunits during methylprednisolone-induced differentiation of leukaemic HL-60 cells.
200011 citationsauthor #5

TIMELINE

2000 11 citations

2005 12 citations

2006 2 citations

2008 61 citations

2009 115 citations

2010 133 citations

2011 1 citations

2012 97 citations

2013 89 citations

2014 26 citations

2015 4 citations

2016 12 citations

2018 7 citations

COAUTHOR MAP

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