B. Wallar

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Aliases
Bradley J. Wallar, Bradley J Wallar, B. J. Wallar, Brad Wallar, B J Wallar
Publication record
66 papers · 3,242 citations · H-index 20

PAPERS

Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter-derived cephalosporinase-33 (ADC-33), a class C β-lactamase present in carbapenem-resistant Acinetobacter baumannii (CRAb)
20252 citationsauthor #2
Synthesis of a Novel Boronic Acid Transition State Inhibitor, MB076: A Heterocyclic Triazole Effectively Inhibits Acinetobacter-Derived Cephalosporinase Variants with an Expanded-Substrate Spectrum
202310 citationsauthor #18
Sulfonamidoboronic Acids as “Cross-Class” Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii
20233 citationsauthor #5
ADC-7 in complex with boronic acid transition state inhibitor PFC_001
20200 citationsauthor #3
1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase
202016 citationsauthor #10
Structural Insights into Inhibition of the Acinetobacter-Derived Cephalosporinase ADC-7 by Ceftazidime and Its Boronic Acid Transition State Analog
20206 citationsauthor #8
1 1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship 2 Study of a Class of β ‑ Lactamase Inhibitors against Acinetobacter 3 baumannii Cephalosporinase
20200 citationsauthor #10
ADC-7 in complex with boronic acid transition state inhibitor S17079
20200 citationsauthor #3
A comprehensive and contemporary “snapshot” of β-lactamases in carbapenem resistant Acinetobacter baumannii
202022 citationsauthor #5
ADC-7 in complex with Beta-lactam antibiotic ceftazidime
20200 citationsauthor #3
ADC-7 in complex with boronic acid transition state inhibitor ME_096
20200 citationsauthor #3
ADC-7 in complex with boronic acid transition state inhibitor S17083
20200 citationsauthor #3
ADC-7 in complex with boronic acid transition state inhibitor S06015
20200 citationsauthor #3
ADC-7 in complex with boronic acid transition state inhibitor LP06
20200 citationsauthor #3
ADC-7 in complex with boronic acid transition state inhibitor CR192
20170 citationsauthor #2
Inhibition of Acinetobacter-Derived Cephalosporinase: Exploring the Carboxylate Recognition Site Using Novel β-Lactamase Inhibitors.
201728 citationsauthor #9
ADC-7 in complex with boronic acid transition state inhibitor CR157
20170 citationsauthor #2
Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C β-Lactamase.
201735 citationsauthor #11
ADC-7 in complex with boronic acid transition state inhibitor S03043
20170 citationsauthor #2
ADC-7 in complex with boronic acid transition state inhibitor CR161
20170 citationsauthor #2
Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefotaxime
20140 citationsauthor #4
Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Cefotaxime
20140 citationsauthor #4
Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Oxacillin
20140 citationsauthor #1
Crystal Structure of AmpC beta-lactamase N152G Mutant from E. coli
20140 citationsauthor #4
Structure of ADC-7 beta-lactamase in complex with boronic acid inhibitor S02030
20140 citationsauthor #2
X-ray crystal structure of the extended-spectrum class C Â²-lactamase, ADC-7, in apo form and in complex with a boronic acid transition state analog
20140 citationsauthor #1
Biochemical and Structural Analysis of Inhibitors Targeting the ADC-7 Cephalosporinase of Acinetobacter baumannii
201434 citationsauthor #9
Crystal structure of ADC-7 beta-lactamase
20140 citationsauthor #2
Session 05 - Engaging Undergraduate Students in Scholarship: Research, Teaching, or Service?
20130 citationsauthor #4
Therapeutics , Targets , and Chemical Biology Small-Molecule Intramimics of Formin Autoinhibition : A New Strategy to Target the Cytoskeletal RemodelingMachinery in Cancer Cells
20130 citationsauthor #2
Probing the role of N152 in the class C beta‐lactamase AmpC
20130 citationsauthor #1
Identification of a Potent Inhibitor for the Extended Spectrum Class C Beta-Lactamase, ADC-7
20130 citationsauthor #3
Probing the Binding Site in the Antibiotic Resistance Enzyme, AmpC Beta-lactamase
20130 citationsauthor #5
Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells.
201329 citationsauthor #2
The X‐ray crystal structure of the Acinetobacter‐Derived Cephalosporinase, ADC‐7, at 1.7 Å
20130 citationsauthor #4
The N152T mutation in the class C beta‐lactamase, AmpC, can serve as a substrate selectivity switch
20130 citationsauthor #4
Probing the Role of Asn 152 in the Class C β- lactamase AmpC
20120 citationsauthor #5
The role of phosphorylation in the regulatory mechanism of the Diaphanous‐related formin, mDia2
20090 citationsauthor #7
The role of phosphorylation in the regulatory mechanism of the Diaphanous‐related formins
20080 citationsauthor #3
Studying Potential Drug Interactions Involved in the Regulation of the Diaphanous-related Formins
20080 citationsauthor #2
Intermediates in the reaction cycle of methane monooxygenase: structure and chemistry
20080 citationsauthor #5
RhoB and the mammalian Diaphanous-related formin mDia2 in endosome trafficking.
2007115 citationsauthor #1
Identification of specific protein regions involved in the regulation of the Diaphanous‐related Formin, DAAM1
20070 citationsauthor #2
Probing important protein interactions in the regulation of cell shape and movement
20060 citationsauthor #1
Probing the specific amino acid residues involved in the regulation of the Diaphanous‐related Formins
20060 citationsauthor #6
The Basic Region of the Diaphanous-autoregulatory Domain (DAD) Is Required for Autoregulatory Interactions with the Diaphanous-related Formin Inhibitory Domain*
2006118 citationsauthor #1
Methane monooxygenase hydroxylase and B component interactions.
200621 citationsauthor #2
A role for mammalian diaphanous-related formins in complement receptor (CR3)-mediated phagocytosis in macrophages.
2005121 citationsauthor #3
Rho GTPase-formin pairs in cytoskeletal remodelling.
200511 citationsauthor #3
EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration
2004599 citationsauthor #7
The formins: active scaffolds that remodel the cytoskeleton.
2003418 citationsauthor #1
Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42.
2003284 citationsauthor #2
Effector proteins from P450(cam) and methane monooxygenase: lessons in tuning nature's powerful reagents.
200326 citationsauthor #2
Methane monooxygenase and compound Q: lessons in oxygen activation
20023 citationsauthor #3
Residues in Methylosinus trichosporium OB3b methane monooxygenase component B involved in molecular interactions with reduced- and oxidized-hydroxylase component: a role for the N-terminus.
200141 citationsauthor #2
Methane monooxygenase component B mutants alter the kinetics of steps throughout the catalytic cycle.
200175 citationsauthor #1
Unmasking of deuterium kinetic isotope effects on the methane monooxygenase compound Q reaction by site-directed mutagenesis of component B.
200145 citationsauthor #2
METHANE MONOOXYGENASE COMPONENT B
19993 citationsauthor #2
Solution structure of component B from methane monooxygenase derived through heteronuclear NMR and molecular modeling.
199961 citationsauthor #2
Dioxygen Activation by Enzymes Containing Binuclear Non-Heme Iron Clusters
199737 citationsauthor #1
Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b
1997234 citationsauthor #4
Structure and reactivity of intermediates in the oxygen activation mechanism of methane monooxygenase
19970 citationsauthor #4
Probing the interactions between component B and the hydroxylase of methane monooxygenase
19970 citationsauthor #1
Dioxygen Activation by Enzymes Containing Binuclear Non-Heme Iron Clusters.
1996845 citationsauthor #1
Roles of component B and reductase in methane monooxygenase (MMO) turnover
19950 citationsauthor #4
Probing the specific amino acid residues involved in the regulation of the Diaphanous‐related Formins
year unknown0 citationsauthor #4

TIMELINE

1995 0 citations

1996 845 citations

1997 271 citations

1999 64 citations

2001 161 citations

2002 3 citations

2003 728 citations

2004 599 citations

2005 132 citations

2006 139 citations

2007 115 citations

2008 0 citations

2009 0 citations

2012 0 citations

2013 29 citations

2014 34 citations

2017 63 citations

2020 44 citations

2023 13 citations

2025 2 citations

Unknown 0 citations

B. Wallar

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