C. Bellamacina

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Aliases
Cornelia R Bellamacina, C. Bellamacina, Cornelia Bellamacina, Cornelia R. Bellamacina, C. R. Bellamacina
Publication record
40 papers · 1,185 citations · H-index 17

PAPERS

K. pneumoniae Topoisomerase IV (ParE-ParC) in complex with DNA and (3S)-10-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-9-fluoro-3-methyl-5-oxo-2,3-dihydro-5H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid (compound 25)
20210 citationsauthor #3
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.
202117 citationsauthor #5
K. pneumoniae Topoisomerase IV (ParE-ParC) in complex with DNA and compound 34 (7-[(1S,5R)-1-amino-3-azabicyclo[3.1.0]hexan-3-yl]-4-(aminomethyl)-1-cyclopropyl-3,6-difluoro-8-methylquinolin-2(1H)-one)
20200 citationsauthor #3
Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
202022 citationsauthor #5
Synthesis and Structure-Activity Relationship of Tetra-Substituted Cyclohexyl Diol Inhibitors of Proviral Insertion of Moloney Virus (PIM) Kinases.
20205 citationsauthor #5
Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline.
201823 citationsauthor #16
CHAIN A. UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase PA-LPXC Complexed with (R)-3-((S)-3-(4-(cyclopropylethynyl)phenyl)-2-oxooxazolidin-5-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)propenamide
20180 citationsauthor #16
Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold.
201618 citationsauthor #8
Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies.
201570 citationsauthor #12
Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor.
201582 citationsauthor #3
ERK2 complexed with N-benzylpyridone tetrahydroazaindazole
20150 citationsauthor #1
ERK2 complexed with a N-H tetrahydroazaindazole
20150 citationsauthor #1
Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase.
201512 citationsauthor #6
ERK2 complexed with 2-pyridiyl tetrahydroazaindazole
20150 citationsauthor #1
Serine/threonine-protein kinase PAK1 complexed with a dibenzodiazepine: identification of an allosteric site on PAK1
20150 citationsauthor #1
Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
2014110 citationsauthor #30
Design, structure-activity relationship, and in vivo characterization of the development candidate NVP-HSP990.
201424 citationsauthor #4
Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990
20140 citationsauthor #1
Pim1 Complexed with a pyridylcarboxamide
20131 citationsauthor #1
Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors.
201349 citationsauthor #5
Pim1 complexed with a novel 3,6-disubstituted indole at 2.6 Ang Resolution
20110 citationsauthor #1
Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases.
201157 citationsauthor #3
Co-crystal structure of the human kinesin Eg5 with a novel tetrahydro-beta-carboline
20090 citationsauthor #2
4-(1H-indazol-5-yl)-6-phenylpyrimidin-2(1H)-one analogs as potent CDC7 inhibitors.
200832 citationsauthor #3
Crystal structure of human Pim1 kinase complexed with 4-(4-hydroxy-3-methyl-phenyl)-6-phenylpyrimidin-2(1H)-one
20080 citationsauthor #1
Structure of porcine pancreatic elastase in 80% isopropanol
20060 citationsauthor #2
Structure of porcine pancreatic elastase in 55% dimethylformamide
20060 citationsauthor #2
Structure of porcine pancreatic elastase in 95% acetone
20060 citationsauthor #2
Targeting cancer: the challenges and successes of structure-based drug design against the human purinome.
200619 citationsauthor #2
Structure of porcine pancreatic elastase in 40% trifluoroethanol
20060 citationsauthor #2
Structure of porcine pancreatic elastase in 40/50/10 cyclohexane
20060 citationsauthor #2
Structure of porcine pancreatic elastase in 80% ethanol
20060 citationsauthor #2
Structure of porcine pancreatic elastase in 40/50/10 % benzene
20060 citationsauthor #2
Multiple solvent crystal structures: probing binding sites, plasticity and hydration.
2006152 citationsauthor #2
Crystal structure at 1.8 A resolution of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis.
200426 citationsauthor #2
SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2.
200352 citationsauthor #2
Purification, crystallization and molecular symmetry of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis.
20022 citationsauthor #2
Molecular interactions in crystal structures of potent inhibitors bound to the kinase domain of Tie-2
20024 citationsauthor #7
The nicotinamide dinucleotide binding motif: a comparison of nucleotide binding proteins
1996234 citationsauthor #1
An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins
1996178 citationsauthor #2

TIMELINE

1996 412 citations

2002 6 citations

2003 52 citations

2004 26 citations

2006 171 citations

2008 32 citations

2009 0 citations

2011 57 citations

2013 50 citations

2014 134 citations

2015 164 citations

2016 18 citations

2018 23 citations

2020 27 citations

2021 17 citations

C. Bellamacina

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