Patterns of microglial cell activation in frontotemporal lobar degeneration

Pathological heterogeneity within patients with frontotemporal lobar degeneration (FTLD) in general precludes the accurate assignment of diagnostic subtype in life. The aim of this study was to assess the extent of microglial cell activation in FTLD in order to determine whether it might be possible to employ this as a diagnostic marker in vivo using PET ligand [11C](R)‐PK11195 in order to differentiate cases of FTLD according to histological subtype.

• Publication year

  2014

• Venue

  Neuropathology and Applied Neurobiology

• Publication date

  2014-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/nan.12092PMID 24117616
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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