Chronic treatment with Δ‐9‐tetrahydrocannabinol alters the structure of neurons in the nucleus accumbens shell and medial prefrontal cortex of rats

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Synapse

• Publication date

  2006-11-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/syn.20313PMID 16881072
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neurotrophic mechanisms in drug addiction

  2007cited by this paper
• The induction of behavioural sensitization is associated with cocaine‐induced structural plasticity in the core (but not shell) of the nucleus accumbens

  2004cited by this paper
• Amphetamine effects on dopamine levels and behavior following cannabinoid exposure during adolescence.

  2004cited by this paper
• Structural plasticity associated with exposure to drugs of abuse.

  2004influential reference
• Structural plasticity and memory

  2004cited by this paper
• Effects of Δ9-THC and WIN-55,212-2 on place preference in the water maze in rats

  2003cited by this paper
• Pre-exposure to the cannabinoid receptor agonist CP 55940 enhances morphine behavioral sensitization and alters morphine self-administration in Lewis rats.

  2003cited by this paper
• Behavioral sensitization to amphetamine follows chronic administration of the CB1 agonist WIN 55,212-2 in Lewis rats.

  2002cited by this paper
• Behavioral sensitization to heroin by cannabinoid pretreatment in the rat.

  2001cited by this paper
• Behavioural sensitization after repeated exposure to Δ9-tetrahydrocannabinol and cross-sensitization with morphine

  2001influential reference
• The psychoactive ingredient of marijuana induces behavioural sensitization

  2001influential reference
• Chronic treatment with Delta(9)-tetrahydrocannabinol enhances the locomotor response to amphetamine and heroin. Implications for vulnerability to drug addiction.

  2001cited by this paper
• Functional Interaction between Opioid and Cannabinoid Receptors in Drug Self-Administration

  2001cited by this paper
• Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse.

  2001cited by this paper
• A cannabinoid mechanism in relapse to cocaine seeking

  2001cited by this paper
• Modulation of transmitter release via presynaptic cannabinoid receptors.

  2001influential reference
• A behavioural model to reveal place preference to Δ9-tetrahydrocannabinol in mice

  2000influential reference
• Cannabinoid receptors and reward in the rat: a conditioned place preference study

  2000cited by this paper
• Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice

  2000influential reference
• Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats

  1999cited by this paper
• Influence of the cannabinoid agonist HU 210 on cocaine- and CQP 201-403-induced behavioural effects in rat.

  1999cited by this paper
• Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice.

  1999cited by this paper
• Pharmacological and biochemical interactions between opioids and cannabinoids.

  1999cited by this paper
• Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine

  1999cited by this paper
• Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats.

  1999cited by this paper
• Effects of Cannabinoids on Dopamine Release in the Corpus Striatum and the Nucleus Accumbens In Vitro

  1999cited by this paper
• Effects of pre-exposure and co-administration of the cannabinoid receptor agonist CP 55,940 on behavioral sensitization to cocaine.

  1998cited by this paper
• Cannabinoid transmission and reward-related events.

  1998influential reference
• Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors.

  1998cited by this paper
• Age, experience and the changing brain.

  1998cited by this paper
• A method for vibratome sectioning of Golgi-Cox stained whole rat brain.

  1998cited by this paper
• Delta9-tetrahydrocannabinol, but not the endogenous cannabinoid receptor ligand anandamide, produces conditioned place avoidance.

  1998cited by this paper
• Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats

  1998cited by this paper
• Age, experience and the changing brain

  1998cited by this paper
• Endogenous cannabinoids as an aversive or counter-rewarding system in the rat.

  1997cited by this paper
• Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra

  1997influential reference
• Persistent Structural Modifications in Nucleus Accumbens and Prefrontal Cortex Neurons Produced by Previous Experience with Amphetamine

  1997cited by this paper
• Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism.

  1997cited by this paper
• Nerve growth factor stimulates growth of cortical pyramidal neurons in young adult rats.

  1997influential reference
• THC-induced place and taste aversions in Lewis and Sprague-Dawley rats.

  1995cited by this paper
• Molecular Neurobiology of Drug Addiction

  1994cited by this paper
• The neural basis of drug craving: an incentive-sensitization theory of addiction.

  1993cited by this paper
• Marijuana's interaction with brain reward systems: update 1991.

  1991cited by this paper
• Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.

  1991cited by this paper
• Δ9-Tetrahydroeannabinol enhances presynaptic dopamine efflux In medial prefrontal cortex

  1990cited by this paper
• Δ9-Tetrahydrocannabinol produces naloxone-blockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis

  1990cited by this paper
• Delta 9-tetrahydrocannabinol enhances presynaptic dopamine efflux in medial prefrontal cortex.

  1990cited by this paper
• The Cortex of the Rat: A Stereotaxic Atlas

  1985cited by this paper
• The Cortex of the Rat

  1985influential reference
• Evironmental effects on cortical dendritic fields. I. Rearing in the dark.

  1968cited by this paper
• The organization of the cerebral cortex

  1957cited by this paper

• Chronic exposure to inhaled vaporized cannabis high in Δ9-THC suppresses Adderall-induced brain activity

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  2023cites this paper
• Peripheral signature of altered synaptic integrity in young onset cannabis use disorder: A proteomic study of circulating extracellular vesicles

  2023cites this paper
• Changes in brain structure and function following chronic exposure to inhaled vaporised cannabis during periadolescence in female and male mice: A multimodal MRI study

  2022cites this paper
• Cannabis in Adolescence: Lasting Cognitive Alterations and Underlying Mechanisms

  2022cites this paper
• Synaptic changes induced by cannabinoid drugs and cannabis use disorder

  2022cites this paper
• Psychotropic drug abuse in pregnancy and its impact on child neurodevelopment: A review

  2022cites this paper
• Chronic adolescent exposure to cannabis in mice leads to sex-biased changes in gene expression networks across brain regions

  2021cites this paper
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• Cannabinoids and Brain Development

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• Mesocorticolimbic system abnormalities in chronic cluster headache patients: A neural signature?

  2021cites this paper
• Cannabinoids, reward processing, and psychosis

  2021cites this paper
• Cognitive Development and Cannabis Use in Adolescents

  2021cites this paper
• Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder

  2020cites this paper
• Impairment of Synaptic Plasticity by Cannabis, Δ9-THC, and Synthetic Cannabinoids.

  2020cites this paper
• Neuronal and synaptic morphological alterations in the hippocampus of cannabinoid receptor type 1 knockout mice

  2020cites this paper
• From Bud to Brain: A Psychiatrist's View of Marijuana

  2020cites this paper
• One Is Not Enough: Understanding and Modeling Polysubstance Use

  2020cites this paper
• The Yin and Yang of Cannabis: A Systematic Review of Human Neuroimaging Evidence of the Differential Effects of Δ9-Tetrahydrocannabinol and Cannabidiol.

  2020cites this paper
• Marijuana Use in Pregnancy: A Review.

  2019cites this paper
• Les liens de causalité entre la consommation de cannabis et la schizophrénie

  2019cites this paper
• Modulation of acute effects of delta-9-tetrahydrocannabinol on psychotomimetic effects, cognition and brain function by previous cannabis exposure.

  2018cites this paper
• Selective effects of Δ9-tetrahydrocannabinol on medium spiny neurons in the striatum

  2018cites this paper
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  2018cites this paper
• Adolescent exposure to Δ9-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons

  2018cites this paper
• Preclinical Studies of Cannabinoid Reward, Treatments for Cannabis Use Disorder, and Addiction-Related Effects of Cannabinoid Exposure

  2018cites this paper
• Associations between adolescent cannabis use and brain structure in psychosis.

  2018cites this paper
• THC alters alters morphology of neurons in medial prefrontal cortex, orbital prefrontal cortex, and nucleus accumbens and alters the ability of later experience to promote structural plasticity

  2018cites this paper
• A Model of Δ9-Tetrahydrocannabinol Self-administration and Reinstatement That Alters Synaptic Plasticity in Nucleus Accumbens.

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  2017cites this paper
• The Role of Cannabinoids in Neuroanatomic Alterations in Cannabis Users.

  2016cites this paper
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  2016cites this paper
• Effects of Marijuana Use on Brain Structure and Function: Neuroimaging Findings from a Neurodevelopmental Perspective.

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• The effects of Δ9-tetrahydrocannabinol on the dopamine system

  2016cites this paper
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  2016cites this paper
• Title Distinct effects of childhood ADHD and cannabis use on brain functional architecture in young adults Permalink

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• Neural mechanisms of sensitivity to peer information in young adult cannabis users

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  2016cites this paper
• Melatonin treatment during the incubation of sensitization attenuates methamphetamine-induced locomotor sensitization and MeCP2 expression.

  2016cites this paper
• Neuroimaging of the dopamine/reward system in adolescent drug use

  2015cites this paper
• Association of Cannabis Use with Depressive Symptoms and Cardiovascular Diseases: A Cross Sectional Analysis DISSERTATION Presented in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy in the Graduate School of The Ohio State University By

  2015cites this paper
• NEURONAL ADAPTATIONS IN THE NUCLEUS ACCUMBENS CORE UNDER ACUTE AND CHRONIC EXPOSURE TO CANNABINOIDS

  2015cites this paper
• Behavioral and Neurochemical Changes in Mesostriatal Dopaminergic Regions of the Rat after Chronic Administration of the Cannabinoid Receptor Agonist WIN55,212-2

  2015cites this paper
• Effects of ethanol exposure and withdrawal on dendritic morphology and spine density in the nucleus accumbens core and shell.

  2015cites this paper
• [Cannabis use among children and adolescents: impacts and consequences].

  2014cites this paper
• Repeated administration of a synthetic cannabinoid receptor agonist differentially affects cortical and accumbal neuronal morphology in adolescent and adult rats

  2014cites this paper
• Cannabis-related working memory deficits and associated subcortical morphological differences in healthy individuals and schizophrenia subjects.

  2014cites this paper
• The association between regular cannabis exposure and alterations of human brain morphology: an updated review of the literature.

  2014cites this paper
• Chronic cannabinoid agonist (WIN 55,212-2) exposure alters hippocampal dentate gyrus spine density in adult rats.

  2014influential citation
• Cannabis Use Is Quantitatively Associated with Nucleus Accumbens and Amygdala Abnormalities in Young Adult Recreational Users

  2014influential citation
• Role of the Endocannabinoid System in Extinction of Learned Behaviours Motivated by Opioid-Induced Reward and Aversion in Rats

  2013cites this paper
• Addiction is Not a Natural Kind

  2013cites this paper
• Dendritic morphology in the striatum and hypothalamus differentially exhibits experience-dependent changes in response to maternal care and early social isolation.

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• Prefrontal endocannabinoid signaling mediates neuroendocrine and behavioral coping responses to stress

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• Effects of Chronic Marijuana Use on Brain Activity During Monetary Decision-Making

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• Withdrawal from THC during adolescence: sex differences in locomotor activity and anxiety.

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• The yin and yang of cannabis-induced psychosis: the actions of Δ(9)-tetrahydrocannabinol and cannabidiol in rodent models of schizophrenia.

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• Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice.

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• Contribution of Pharmacology to Development of Monoaminergic Hypotheses of Depression

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• Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress.

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• Altered Mesolimbic Dopamine System in THC Dependence

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• PRECLINICAL STUDY: FULL ARTICLE: Altered architecture and functional consequences of the mesolimbic dopamine system in cannabis dependence

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• Altered Frontal Cortical Volume and Decision Making in Adolescent Cannabis Users

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• Functional interactions between endogenous cannabinoid and opioid systems: focus on alcohol, genetics and drug-addicted behaviors.

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• Back to the future: rehabilitation of children after brain injury

  2010cites this paper
• Cannabinoids, opioids and MDMA: neuropsychological interactions related to addiction.

  2010cites this paper
• Behavioural disturbances and altered Fos protein expression in adult rats after chronic pubertal cannabinoid treatment.

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• Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood

  2009cites this paper
• The Endocannabinoid System is a Major Player in Schizophrenia

  2008cites this paper
• The impact of social isolation on rat behaviour

  2008cites this paper
• Cannabinoids and the brain

  2008cites this paper
• Behavioral sensitization to Δ9‐tetrahydrocannabinol and cross‐sensitization with morphine: differential changes in accumbal shell and core dopamine transmission

  2008influential citation
• Continuous nicotine administration produces selective, age‐dependent structural alteration of pyramidal neurons from prelimbic cortex

  2008cites this paper
• The pharmacology of the endocannabinoid system: functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction

  2008cites this paper
• Chronic treatment and withdrawal of the cannabinoid agonist WIN 55,212-2 modulate the sensitivity of presynaptic receptors involved in the regulation of monoamine syntheses in rat brain

  2008cites this paper
• Locomotor effects of morphine or alcohol in mice after a repeated treatment with the cannabinoid agonist HU 210.

  2008cites this paper
• Effects of haloperidol on the behavioral, subjective, cognitive, motor, and neuroendocrine effects of Δ-9-tetrahydrocannabinol in humans

  2008cites this paper
• Behavioral pharmacology of cannabinoids with a focus on preclinical models for studying reinforcing and dependence-producing properties.

  2008cites this paper
• Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine

  2007cites this paper
• Of rats and schizophrenia.

  2007cites this paper
• Cannabis and psychosis: an update on course and biological plausible mechanisms

  2007cites this paper
• THE ANATOMICAL AND BEHAVIOURAL CORRELATES OF EXPERIENCE

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• Neurobiological effects of early life cannabis exposure in relation to the gateway hypothesis

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• Acute, chronic and withdrawal effects of the cannabinoid receptor agonist WIN55212‐2 on the sequential activation of MAPK/Raf‐MEK‐ERK signaling in the rat cerebral frontal cortex: Short‐term regulation by intrinsic and extrinsic pathways

  2007cites this paper