Kindlin-2 directly binds actin and regulates integrin outside-in signaling

Bledzka et al. show that kindlin-2 binds actin via its F0 domain, and mutation of this site diminishes cell spreading, revealing a new mechanism by which kindlin-2 regulates cellular responses.

• Publication year

  2016

• Venue

  Journal of Cell Biology

• Publication date

  2016-04-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201501006PMID 27044892PMCID 4828686
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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