Ethnically Tibetan women in Nepal with low hemoglobin concentration have better reproductive outcomes

Jang-ik Cho,B. Basnyat,Choongwon Jeong,A. Di Rienzo,G. Childs,S. Craig,Jiayang Sun,C. Beall

Published 2017 in Evolution, Medicine and Public Health

ABSTRACT

Elevated maternal hemoglobin concentration associated strongly with lower lifetime reproductive success among ethnically Tibetan women at 3000-4100m in Nepal. These findings are consistent with the hypothesis that unelevated hemoglobin concentration is an adaptation shaped by natural selection resulting in low hemoglobin levels among Tibetans compared with visitors and Andean highlanders.

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