A new member of the cationic dinitrosyl iron complexes family incorporating N-ethylthiourea is effective against human HeLa and MCF-7 tumor cell lines

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Coordination Chemistry

• Publication date

  2016-02-17

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1080/00958972.2016.1142536
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Thiourea.

  2020cited by this paper
• Software update: the ORCA program system, version 4.0

  2018cited by this paper
• Nitrosyl iron complexes with enhanced NO donating ability: synthesis, structure and properties of a new type of salt with the DNIC cations [Fe(SC(NH2)2)2(NO)2]+

  2015cited by this paper
• New ruthenium(II) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity.

  2014cited by this paper
• Interaction of ferrocene appended Ru(II), Rh(III) and Ir(III) dipyrrinato complexes with DNA/protein, molecular docking and antitumor activity.

  2014cited by this paper
• Mesomeric tautomerism of ligand is a novel pathway for synthesis of cationic dinitrosyl iron complexes: Х-ray structure and properties of nitrosyl complex with thiourea

  2014cited by this paper
• A review on the chemistry, coordination, structure and biological properties of 1-(acyl/aroyl)-3-(substituted) thioureas

  2014cited by this paper
• DNA binding and anti-cancer activity of redox-active heteroleptic piano-stool Ru(II), Rh(III), and Ir(III) complexes containing 4-(2-methoxypyridyl)phenyldipyrromethene.

  2013cited by this paper
• Next-generation metal anticancer complexes: multitargeting via redox modulation.

  2013cited by this paper
• Nitric oxide donors: spermine/NO and diethylenetriamine/NO induce ovarian cancer cell death and affect STAT3 and AKT signaling proteins.

  2013cited by this paper
• Synthesis, molecular structure, computational study and in vitro anticancer activity of dinuclear thiolato-bridged pentamethylcyclopentadienyl Rh(III) and Ir(III) complexes.

  2013cited by this paper
• Lead optimization of an acylhydrazone scaffold possessing antiviral activity against Lassa virus.

  2013cited by this paper
• Synthesis, structure, NO donor activity of iron–sulfur nitrosyl complex with 2-aminophenol-2-yl and its antiproliferative activity against human cancer cells

  2013cited by this paper
• Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells

  2012cited by this paper
• Metals in Medicine

  2012cited by this paper
• Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.

  2012cited by this paper
• Comparative characteristics of new lines of mesenchymal stem cells derived from human embryonic stem cells, bone marrow, and foreskin

  2012cited by this paper
• Designing organometallic compounds for catalysis and therapy.

  2012cited by this paper
• Application of ferrocene and its derivatives in cancer research

  2011cited by this paper
• Metal complexes as DNA intercalators.

  2011cited by this paper
• Metal-based antitumour drugs in the post-genomic era: what comes next?

  2011cited by this paper
• Nitrosyl iron complexes--synthesis, structure and biology.

  2011cited by this paper
• Cytotoxic properties of the nitrosyl iron complex with phenylthiyl

  2011cited by this paper
• Antitumor Actions of Ruthenium(III)-Based Nitric Oxide Scavengers and Nitric Oxide Synthase Inhibitors

  2011cited by this paper
• Peptide-bound dinitrosyliron complexes (DNICs) and neutral/reduced-form Roussin's red esters (RREs/rRREs): understanding nitrosylation of [Fe-S] clusters leading to the formation of DNICs and RREs using a de novo design strategy.

  2011cited by this paper
• The unusual electronic structure of dinitrosyl iron complexes.

  2010cited by this paper
• Chymase mediates paraquat-induced collagen production in human lung fibroblasts.

  2010cited by this paper
• Ferrocene-Promoted Photoactivated DNA Cleavage and Anticancer Activity of Terpyridyl Copper(II) Phenanthroline Complexes

  2010cited by this paper
• Synthesis and biological activities of transition metal complexes based on acetylsalicylic acid as neo-anticancer agents.

  2010cited by this paper
• New members of the {Fe(NO)2}10 dinitrosyliron complexes bound with [thiolate, thiolate] and [amide, amide] ligations.

  2010cited by this paper
• Organometallic Anticancer Compounds

  2010cited by this paper
• Calibration of modern density functional theory methods for the prediction of 57Fe Mössbauer isomer shifts: meta-GGA and double-hybrid functionals.

  2009cited by this paper
• Nitric oxide: cancer target or anticancer agent?

  2009cited by this paper
• Nitric oxide--a novel therapeutic for cancer.

  2008cited by this paper
• Reactions of synthetic [2Fe-2S] and [4Fe-4S] clusters with nitric oxide and nitrosothiols.

  2008cited by this paper
• The ruthenium(II)–arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53–JNK pathways

  2008cited by this paper
• Synthesis of dinitrosyl iron complexes (DNICs) with intramolecular hydrogen bonding

  2008cited by this paper
• Biochemical mechanisms of cisplatin cytotoxicity.

  2007cited by this paper
• Dinitrosyl iron complexes [E5Fe(NO)2]− (E = S, Se): A precursor of Roussin’s black salt [Fe4E3(NO)7]−

  2006cited by this paper
• Transformation and structural discrimination between the neutral {Fe(NO)2}10 dinitrosyliron complexes (DNICs) and the anionic/cationic {Fe(NO)2}9 DNICs.

  2006cited by this paper
• A study of the topoisomerase II activity in HIV-1 replication using the ferrocene derivatives as probes.

  2006cited by this paper
• Mononitrosyl tris(thiolate) iron complex [Fe(NO)(SPh)3]- and dinitrosyl iron complex [(EtS)2Fe(NO)2]-: formation pathway of dinitrosyl iron complexes (DNICs) from nitrosylation of biomimetic rubredoxin [Fe(SR)4]2-/1- (R = Ph, Et).

  2006cited by this paper
• DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators

  2006cited by this paper
• Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes.

  2005cited by this paper
• Binding of Organometallic Ruthenium(II) and Osmium(II) Complexes to an Oligonucleotide: A Combined Mass Spectrometric and Theoretical Study

  2005cited by this paper
• YC-1 [3-(5′-Hydroxymethyl-2′-furyl)-1-benzyl Indazole] Inhibits Endothelial Cell Functions Induced by Angiogenic Factors in Vitro and Angiogenesis in Vivo Models

  2005cited by this paper
• Dinitrosyl iron complexes (DNICs) [L(2)Fe(NO)2]- (L = thiolate): interconversion among {Fe(NO)2}9 DNICs, {Fe(NO)2}10 DNICs, and [2Fe-2S] clusters, and the critical role of the thiolate ligands in regulating NO release of DNICs.

  2005cited by this paper
• Bioorganometallic chemistry of ferrocene.

  2004cited by this paper
• Nitric-oxide-donating NSAIDs as agents for cancer prevention.

  2004cited by this paper
• Photochemistry of the dinitrosyl iron complex [S5Fe(NO)2]- leading to reversible formation of [S5Fe(mu-S)2FeS5]2-: spectroscopic characterization of species relevant to the nitric oxide modification and repair of [2Fe-2S] ferredoxins.

  2004cited by this paper
• The first organometallic selective estrogen receptor modulators (SERMs) and their relevance to breast cancer.

  2004cited by this paper
• New metal complexes as potential therapeutics.

  2003cited by this paper
• YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.

  2003cited by this paper
• Nitric oxide donor increases the efficiency of cytostatic therapy and retards the development of drug resistance.

  2003cited by this paper
• Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide.

  2002cited by this paper
• Non-heme iron nitrosyls in biology.

  2002cited by this paper
• Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process.

  2002cited by this paper
• Influence of the nitric oxide donor glyceryl trinitrate on apoptotic pathways in human colon cancer cells.

  2002cited by this paper
• Donors of NO and pulsed radiation at λ=820 nm exert effects on cell attachment to extracellular matrices

  2001cited by this paper
• Recent studies in the coordination chemistry of heterocyclic thiones and thionates

  2001cited by this paper
• Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-1 cells

  2001cited by this paper
• On the mechanism of the antitumor activity of ferrocenium derivatives

  2000cited by this paper
• Medicinal applications of heavy-metal compound

  1999cited by this paper
• Carboxylation of Kinetically Inert Platinum(IV) Hydroxy Complexes. An Entr.acte.ee into Orally Active Platinum(IV) Antitumor Agents.

  1995cited by this paper
• Fully optimized contracted Gaussian basis sets for atoms Li to Kr

  1992cited by this paper
• Density-functional exchange-energy approximation with correct asymptotic behavior.

  1988cited by this paper
• Organometallics

  1987cited by this paper
• Density-functional approximation for the correlation energy of the inhomogeneous electron gas.

  1986cited by this paper
• Synthese und Struktur von [Fe(SPh)2(NO)2]- dem „Monomeren“ des Roussinschen Phenylesters/ Synthesis and Structure of [Fe(SPh)2(NO)2]- , the “Monomer” of Roussin’s Phenyl Ester

  1986cited by this paper
• a. K. a.

  1984cited by this paper
• Gastroenterology.

  1976cited by this paper
• A human cell line from a pleural effusion derived from a breast carcinoma.

  1973cited by this paper
• Organic solvents;: Physical properties and methods of purification

  1970cited by this paper
• STUDIES ON THE PROPAGATION IN VITRO OF POLIOMYELITIS VIRUSES

  1953cited by this paper
• Preparation of nitric oxide: some laboratory methods.

  1949cited by this paper

• Redox-Regulated Cell Response Mechanisms to Nitrosyl Iron Complex with N-Ethylthiourea in Human Mesenchymal Stem Cells In Vitro

  2025cites this paper
• Activation of Transcription Factor Nrf2 in HeLa Cells under the Action of Nitrosyl Iron Complex with N-Ethylthiourea

  2024cites this paper
• Theoretical study of stability of dinitrosyl iron(i) complexes with thiocarbonyl ligands

  2024cites this paper
• Aerobic decomposition of dimethylthiourea nitrosyl iron complex in the presence of albimin and glutathione

  2024cites this paper
• Thio ligand binding in dinitrosyl iron-sulfur complexes: Quantitative structure–activity relationships

  2024cites this paper
• Effect of the dinitrosyl iron complex with N-ethylthiourea on ROS and NO intracellular levels and caspase activity in HeLa tumor cells

  2023cites this paper
• Nitrosyl iron complex with N-ethylthiourea ligands: reactions with hemoglobin

  2023cites this paper
• NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives

  2023cites this paper
• Anionic dinitrosyl iron complexes – new nitric oxide donors with selective toxicity to human glioblastoma cells

  2022cites this paper
• The Influence of Cationic Nitrosyl Iron Complex with Penicillamine Ligands on Model Membranes, Membrane-Bound Enzymes and Lipid Peroxidation

  2022cites this paper
• Influence of alkyl substituents in cations of mononuclear dinitrosyliron complexes containing thiourea ligands on the mechanism of the reaction with molecular oxygen: a quantum chemical study

  2022cites this paper
• Features of the decomposition of the nitrosyl iron complex with thiourea ligands under aerobic conditions: experiment and kinetic and quantum chemical modeling

  2022cites this paper
• Effect of solvents and glutathione on the decomposition of the nitrosyl iron complex with N-ethylthiourea ligands: An experimental and theoretical study.

  2022cites this paper
• Synthesis, structure and antibacterial activity of dinitrosyl iron complexes (DNICs) dimers functionalized with 5-(nitrophenyl) -4-H-1,2,4-triazole-3-thiolyls

  2022cites this paper
• Features of the decomposition of cationic nitrosyl iron complexes with N-ethylthiourea and penicillamine ligands in the presence of albumin

  2021cites this paper
• Investigation of the interaction of the cationic nitrosyl iron complex [Fe(SC(NH2)2)2(NO)2]+ with molecular oxygen

  2021cites this paper
• Insight into the Electronic Structure of Biomimetic Dinitrosyliron Complexes (DNICs): Toward the Syntheses of Amido-Bridging Dinuclear DNICs.

  2021cites this paper
• AСETAMIDE AND NICOTINIC ACID OF МОNOTYPE LIGAND COORDINATION COMPOUNDS OF ZINC NITRATE

  2021cites this paper
• Formation of supramolecular synthons in the crystalline structure of the dinitrosyl iron complexes with aliphatic thiourea ligands

  2020cites this paper
• Effect of albumin on the transformation of dinitrosyl iron complexes with thiourea ligands.

  2020cites this paper
• Recent advances in the chemistry of iron-based chemotherapeutic agents

  2020cites this paper
• Decomposition of the binuclear nitrosyl iron complex with thiosulfato ligands in aqueous solutions: Experimental and theoretical study

  2020cites this paper
• Quantum chemical modeling in the system polyvinylpyrrolidone—cation of the dinitrosyl iron complex

  2020cites this paper
• New agent for nitric oxide (NO) chemotherapy: Synthesis and properties of DNIC with hydrazinium cation in solid phase and solutions

  2019cites this paper
• Benzamide coordination compounds of magnesium nicotinate

  2019cites this paper
• Redox reactions of cationic nitrosyl iron complexes with thiourea and its aliphatic derivatives: The experiment and DFT investigation

  2019cites this paper
• Cytoprotective Effects of Dinitrosyl Iron Complexes on Viability of Human Fibroblasts and Cardiomyocytes

  2019cites this paper
• Antibacterial activity of [1Fe-2S]- and [2Fe-2S]-nitrosyl complexes as nitric oxide donors

  2019cites this paper
• Transformation of mononuclear dinitrosyl iron complex (DNIC) with thiourea in glutathione aqueous solution

  2019cites this paper
• Fe in biosynthesis, translocation, and signal transduction of NO: toward bioinorganic engineering of dinitrosyl iron complexes into NO-delivery scaffolds for tissue engineering.

  2019cites this paper
• The antitumor effect of dinitrosyl iron complexes with glutathione in a murine solid-tumor model

  2017cites this paper
• The cationic dinitrosyl iron complexes family with thiocarbamide derivatives: Synthesis, structure and properties in the solid state

  2017cites this paper
• NO-Donor Iron Nitrosyl Complex with N-Ethylthiourea Ligand Exhibits Selective Toxicity to Glioma A172 Cells

  2017cites this paper