Qualitative and Quantitative Analysis of Paracetamol in Different Drug Samples by HPLC Technique

HPLC is rapid more accurate,purity checking & separation method of paracetamolin different drug sample as compare with standard reference& sample solution within complies with Indian Pharmacopeia. This method is applicable to Forensic science laboratories also. It is very sensitive less time consumable but sharp peaks recorded. Chromatographic technique - stainless still column 20cm x 4.6mm packed with ocadesilance bonded to porous silica 10 micrometer. Flow rates 0.2ml /min. at 20 micrometer loop injector & spectrophoto- meter set at 272 nm. Retention time of std 4-ammino phenol & sample solution 4.388 & 4.542 respectively. La- beled amount 102.86% of paracetamol was observed. The % is indicated that the paracetamol is within limit of Indian pharmacopeia. Identification: Sample given Indian pharmacopeia identification test for the presence of paracetamol.

• Publication year

  2014

• Venue

  IOSR Journal of Applied Chemistry

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.9790/5736-07814649
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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