Bcl-2 Family Gene Expression during Severe Hyperoxia Induced Lung Injury

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Laboratory Investigation

• Publication date

  2000-12-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1038/labinvest.3780195PMID 11140697
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen.

  2015influential reference
• p53-independent induction of GADD45 and GADD153 in mouse lungs exposed to hyperoxia.

  2000cited by this paper
• Oxygen induces S-phase growth arrest and increases p53 and p21(WAF1/CIP1) expression in human bronchial smooth-muscle cells.

  1999cited by this paper
• Apoptosis and DNA damage in type 2 alveolar epithelial cells cultured from hyperoxic rats.

  1998cited by this paper
• Caspases: enemies within.

  1998cited by this paper
• Accumulation of p21Cip1/WAF1 during Hyperoxic Lung Injury in Mice

  1998cited by this paper
• Exposure to hyperoxia induces p53 expression in mouse lung epithelium.

  1998cited by this paper
• Inflammatory and epithelial responses in mouse strains that differ in sensitivity to hyperoxic injury.

  1998cited by this paper
• The Bcl-2 protein family: arbiters of cell survival.

  1998cited by this paper
• A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

  1998cited by this paper
• Accumulation of p21(Cip1/WAF1) during hyperoxic lung injury in mice.

  1998cited by this paper
• Apoptosis and DNA damage in type 2 alveolar epithelial cells cultured from hyperoxic rats.

  1998cited by this paper
• Oxygen toxicity in mouse lung: pathways to cell death.

  1998influential reference
• Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation.

  1998influential reference
• Cell death throes.

  1998cited by this paper
• The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis.

  1998cited by this paper
• Temporal changes in expression of TGF-beta isoforms in mouse lung exposed to oxygen.

  1997cited by this paper
• Apoptosis and necrosis in toxicology: a continuum or distinct modes of cell death?

  1997cited by this paper
• Cellular Oxygen Toxicity

  1996cited by this paper
• A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

  1996cited by this paper
• In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

  1995cited by this paper
• Vascular endothelial growth factor mRNA increases in alveolar epithelial cells during recovery from oxygen injury.

  1995cited by this paper
• BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

  1994cited by this paper
• Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.

  1993cited by this paper
• In situ end‐labelling detects DNA strand breaks in apoptosis and other physiological and pathological states

  1993cited by this paper
• Distinct effects of oxygen on surfactant protein B expression in bronchiolar and alveolar epithelium.

  1992cited by this paper
• Reversed anion selectivity in cultured cystic fibrosis sweat duct cells.

  1992cited by this paper
• Morphologic changes in pulmonary oxygen toxicity.

  1986cited by this paper
• Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation.

  1984cited by this paper
• Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics

  1972cited by this paper
• Oxygen poisoning in mice. Ultrastructural and surfactant studies during exposure and recovery.

  1970influential reference

• Blockade of caspase cascade overcomes malaria-associated acute respiratory distress syndrome in mice

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  2018cites this paper
• Probucol attenuates hyperoxia-induced lung injury in mice

  2017cites this paper
• Hyperoxia in the Pathogenesis of Bronchopulmonary Dysplasia

  2016cites this paper
• Protective Effects of Valproic Acid, a Histone Deacetylase Inhibitor, against Hyperoxic Lung Injury in a Neonatal Rat Model

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• Edaravone protects rats and human pulmonary alveolar epithelial cells against hyperoxia injury: heme oxygenase-1 and PI3K/Akt pathway may be involved

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  2014cites this paper
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  2014cites this paper
• Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.

  2013cites this paper
• Effect of Short-term Exposure of Different Concentrations of Hyperoxia on Fetal Alveolar Type II Cell Death.

  2013cites this paper
• TLR Signaling Prevents Hyperoxia-Induced Lung Injury by Protecting the Alveolar Epithelium from Oxidant-Mediated Death

  2012cites this paper
• Epithelium from Oxidant-Mediated Death Lung Injury by Protecting the Alveolar TLR Signaling Prevents Hyperoxia-Induced

  2012cites this paper
• Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide

  2012cites this paper
• Carotid body growth during chronic postnatal hyperoxia.

  2012cites this paper
• Hydrogen-rich saline provides protection against hyperoxic lung injury.

  2011cites this paper
• Cathepsin B is activated as an executive protease in fetal rat alveolar type II cells exposed to hyperoxia

  2011cites this paper
• Bcl-XL Is the primary mediator of p21 protection against hyperoxia-induced cell death

  2011cites this paper
• Effect of recombinant IL-10 on cultured fetal rat alveolar type II cells exposed to 65%-hyperoxia

  2011cites this paper
• The chitinase-like proteins breast regression protein-39 and YKL-40 regulate hyperoxia-induced acute lung injury.

  2010cites this paper
• Cell Injury , Repair , Aging and Apoptosis p 21 Cip 1 Protection against Hyperoxia Requires Bcl-XL and Is Uncoupled from Its Ability to Suppress Growth

  2010cites this paper
• Hyperoxia-derived lung damage in preterm infants.

  2010cites this paper
• Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development.

  2010cites this paper
• IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins.

  2009cites this paper
• Proteomic analysis of human macrophages exposed to hypochlorite-oxidized low-density lipoprotein.

  2009cites this paper
• Apoptosis in Lung Injury and Disease

  2009cites this paper
• Deleterious role of TLR3 during hyperoxia-induced acute lung injury.

  2008cites this paper
• Retinoblastoma function is essential for establishing lung epithelial quiescence after injury.

  2008cites this paper
• Molecular mechanisms of hyperoxia-induced acute lung injury.

  2008cites this paper
• The Fas system confers protection against alveolar disruption in hyperoxia-exposed newborn mice.

  2008cites this paper
• THE TIME COURSE OF EXPRESSION OF GENES INVOLVED IN SPECIFIC PATHWAYS IN NORMAL HUMAN BRONCHIAL EPITHELIAL CELLS FOLLOWING EXPOSURE TO CIGARETTE SMOKE

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• Mechanisms of Cell Death in Oxidative Stress

  2007cites this paper
• Hyperoxia-induced signal transduction pathways in pulmonary epithelial cells.

  2007cites this paper
• The Role of Angiopoietin 2 in Hyperoxia-Inuduced Acute Lung Injury

  2007cites this paper
• Increased Hyperoxia-Induced Mortality and Acute Lung Injury in IL-13 Null Mice1

  2007cites this paper
• Apoptosis of T-leukemia and B-myeloma cancer cells induced by hyperbaric oxygen increased phosphorylation of p38 MAPK.

  2007cites this paper
• Type II epithelial cells are critical target for hyperoxia-mediated impairment of postnatal lung development.

  2006cites this paper
• Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

  2006cites this paper
• Bcl-X L and Is Uncoupled from Its Ability to Suppress Growth

  2006cites this paper
• p21Cip1/Waf1/Sdi1 protects against hyperoxia by maintaining expression of Bcl-XL

  2006cites this paper
• p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L).

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• Poly(ADP-ribose)polymerase activation mediates lung epithelial cell death in vitro but is not essential in hyperoxia-induced lung injury.

  2005cites this paper
• DNA repair proteins as molecular therapeutics for oxidative and alkylating lung injury.

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• Hyperoxia-induced apoptosis and Fas/FasL expression in lung epithelial cells.

  2005cites this paper
• Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury.

  2005cites this paper
• Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice.

  2004cites this paper
• Comparison of mammary gland involution between 129S1 and C57BL/6 inbred mouse strains: differential regulation of Bcl2a1, Trp53, Cebpb, and Cebpd expression

  2004cites this paper
• Mitochondrial cytochrome c release is a key event in hyperoxia-induced lung injury: protection by cyclosporin A.

  2004cites this paper
• Pathways of cell signaling in hyperoxia.

  2003cites this paper
• Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/Bid Pathway*

  2003cites this paper
• Gene expression profiling of the early pulmonary response to hyperoxia in mice.

  2003cites this paper
• Effect of indomethacin on induction of apoptosis in colonic cancer cell line SW480 transferred by wild-type p53 gene

  2003cites this paper
• Protection of lungs from hyperoxic injury: gene expression analysis of cyclosporin A therapy.

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• Hyperoxia Alters Phorbol Ester-Induced Phospholipase D Activation in Bovine Lung Microvascular Endothelial Cells

  2003cites this paper
• Wild-type levels of the mouse Forkhead Box f1 gene are essential for lung repair.

  2002cites this paper
• Hyperoxia-induced Apoptosis Does Not Require Mitochondrial Reactive Oxygen Species and Is Regulated by Bcl-2 Proteins*

  2002cites this paper
• Normal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1).

  2002cites this paper
• DNA oxidation or apoptosis: will the real culprit of dna damage in hyperoxic lung injury please stand up?

  2002cites this paper
• Blocking neutrophil influx reduces DNA damage in hyperoxia-exposed newborn rat lung.

  2002cites this paper
• Will the Real Culprit of DNA Damage in Hyperoxic Lung Injury Please Stand Up

  2002cites this paper
• DNA damage and cell cycle checkpoints in hyperoxic lung injury: braking to facilitate repair.

  2001influential citation
• p53-dependent induction of p21(Cip1/WAF1/Sdi1) protects against oxygen-induced toxicity.

  2001cites this paper