Correlation of spindle architecture with dynamic behavior shows that pairs of antiparallel microtubules are sufficient to form a bipolar spindle, whereas interpolar microtubules maintain the speed of pole displacement during spindle assembly. The number of interpolar microtubules formed is controlled in part through γ-tubulin phosphorylation.
Distinct roles for antiparallel microtubule pairing and overlap during early spindle assembly
Elena Nazarova,E. O'Toole,Susanne Kaitna,P. François,M. Winey,J. Vogel
Published 2013 in Molecular Biology of the Cell
ABSTRACT
PUBLICATION RECORD
- Publication year
2013
- Venue
Molecular Biology of the Cell
- Publication date
2013-10-15
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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