The association between 2D:4D ratio and cognitive empathy is contingent on a common polymorphism in the oxytocin receptor gene (OXTR rs53576).

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Psychoneuroendocrinology

• Publication date

  2015-08-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1016/j.psyneuen.2015.04.007PMID 25935637
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Oxytocin, testosterone, and human social cognition

  2016cited by this paper
• Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism

  2015cited by this paper
• Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain

  2015cited by this paper
• Oxytocin Receptor Gene Methylation: Converging Multilevel Evidence for a Role in Social Anxiety

  2015cited by this paper
• Oxytocin-augmented labor and risk for autism in males.

  2015cited by this paper
• Genomic conflicts and sexual antagonism in human health: insights from oxytocin and testosterone

  2015cited by this paper
• Oxytocin receptor and vasopressin receptor 1a genes are respectively associated with emotional and cognitive empathy.

  2015cited by this paper
• Dissociable contribution of prefrontal and striatal dopaminergic genes to learning in economic games

  2014cited by this paper
• Oxytocin and vasopressin support distinct configurations of social synchrony.

  2014cited by this paper
• Oxytocin administration, salivary testosterone, and father-infant social behavior.

  2014cited by this paper
• Oxytocin Promotes Facial Emotion Recognition and Amygdala Reactivity in Adults with Asperger Syndrome

  2014cited by this paper
• Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder

  2014cited by this paper
• Variation in oxytocin receptor gene (OXTR) polymorphisms is associated with emotional and behavioral reactions to betrayal.

  2014cited by this paper
• The development of the neural substrates of cognitive control in adolescents with autism spectrum disorders.

  2014cited by this paper
• Social cognition, face processing, and oxytocin receptor single nucleotide polymorphisms in typically developing children

  2014cited by this paper
• Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: A 13-year longitudinal study

  2014cited by this paper
• A sociability gene? Meta-analysis of oxytocin receptor genotype effects in humans

  2014cited by this paper
• Elevated fetal steroidogenic activity in autism

  2014cited by this paper
• Oxytocin receptor gene variation predicts empathic concern and autonomic arousal while perceiving harm to others

  2014cited by this paper
• Analysis of gastrin-releasing peptide gene and gastrin-releasing peptide receptor gene in patients with agoraphobia.

  2014cited by this paper
• Oxytocin and social salience: a call for gene-environment interaction research

  2013cited by this paper
• Oxytocin effects on the human brain: findings, questions, and future directions.

  2013cited by this paper
• Neural mechanisms of oxytocin receptor gene mediating anxiety-related temperament

  2013cited by this paper
• Associations between the oxytocin receptor gene (OXTR) and “mind-reading” in humans—An exploratory study

  2013influential reference
• The “Reading the Mind in the Eyes” test: Systematic review of psychometric properties and a validation study in Italy

  2013cited by this paper
• Parental Oxytocin and Early Caregiving Jointly Shape Children’s Oxytocin Response and Social Reciprocity

  2013cited by this paper
• Family environment and adult resilience: contributions of positive parenting and the oxytocin receptor gene

  2013cited by this paper
• Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills

  2013cited by this paper
• Prenatal and postnatal hormone effects on the human brain and cognition

  2013cited by this paper
• Oxytocin administration alters HPA reactivity in the context of parent-infant interaction.

  2013cited by this paper
• The neural and hormonal bases of human parental care.

  2013cited by this paper
• Impact of maternal depression across the first 6 years of life on the child's mental health, social engagement, and empathy: The moderating role of oxytocin.

  2013cited by this paper
• Plasma oxytocin distributions in a large cohort of women and men and their gender-specific associations with anxiety.

  2013cited by this paper
• Association between OXTR and clinical phenotypes of autism spectrum disorders.

  2013cited by this paper
• Oxytocin administration to parent enhances infant physiological and behavioral readiness for social engagement.

  2012cited by this paper
• The animal and human neuroendocrinology of social cognition, motivation and behavior

  2012cited by this paper
• Oxytocin plasma concentrations after single intranasal oxytocin administration - a study in healthy men.

  2012cited by this paper
• The contributions of oxytocin and vasopressin pathway genes to human behavior.

  2012cited by this paper
• Modulating social behavior with oxytocin: how does it work? What does it mean?

  2012cited by this paper
• Does the oxytocin receptor polymorphism (rs2254298) confer 'vulnerability' for psychopathology or 'differential susceptibility'? insights from evolution

  2012cited by this paper
• New evidence on testosterone and cooperation

  2012cited by this paper
• Acute effects of steroid hormones and neuropeptides on human social-emotional behavior: a review of single administration studies.

  2012cited by this paper
• Oxytocin and social affiliation in humans.

  2012cited by this paper
• New evidence on testosterone and cooperation: reply

  2012cited by this paper
• Intranasal oxytocin administration is reflected in human saliva.

  2012cited by this paper
• Oxytocin-Motivated Ally Selection is Moderated by Fetal Testosterone Exposure and Empathic Concern

  2012cited by this paper
• A sniff of trust: meta-analysis of the effects of intranasal oxytocin administration on face recognition, trust to in-group, and trust to out-group.

  2012cited by this paper
• Oxytocin receptor gene (OXTR) is related to psychological resources

  2011influential reference
• Oxytocin and social motivation.

  2011cited by this paper
• Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

  2011cited by this paper
• Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans

  2011cited by this paper
• Testosterone administration impairs cognitive empathy in women depending on second-to-fourth digit ratio

  2011influential reference
• Religion and Well-being

  2011cited by this paper
• No Association between Oxytocin Receptor (OXTR) Gene Polymorphisms and Experimentally Elicited Social Preferences

  2010cited by this paper
• Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking

  2010cited by this paper
• A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function

  2010influential reference
• Minireview: Organizational hypothesis: instances of the fingerpost.

  2010cited by this paper
• Dopaminergic-neuropeptide interactions in the social brain.

  2009cited by this paper
• Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans

  2009influential reference
• Fetal Testosterone Predicts Sexually Differentiated Childhood Behavior in Girls and in Boys

  2009cited by this paper
• Oxytocin receptor polymorphisms and adult attachment style in patients with depression.

  2009cited by this paper
• Gender differences in financial risk aversion and career choices are affected by testosterone

  2009cited by this paper
• Brief communication: Familial resemblance in digit ratio (2D:4D).

  2009cited by this paper
• Fingers as a marker of prenatal androgen exposure.

  2009cited by this paper
• The developmental origins of a disposition toward empathy: Genetic and environmental contributions.

  2008cited by this paper
• Association between the oxytocin receptor (OXTR) gene and autism: relationship to Vineland Adaptive Behavior Scales and cognition

  2008cited by this paper
• Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting.

  2008cited by this paper
• Sex differences in oxytocin and vasopressin: implications for autism spectrum disorders?

  2007cited by this paper
• Second to fourth digit length ratio (2D:4D) and adult sex hormone levels: new data and a meta-analytic review.

  2007cited by this paper
• Parent-infant synchrony and the construction of shared timing; physiological precursors, developmental outcomes, and risk conditions.

  2007cited by this paper
• Oxytocin improves "mind-reading" in humans.

  2007influential reference
• Digit Ratio (2D:4D) in Twins: Heritability Estimates and Evidence for a Masculinized Trait Expression in Women from opposite-Sex Pairs

  2007cited by this paper
• Testosterone administration reduces empathetic behavior: a facial mimicry study.

  2006cited by this paper
• Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population.

  2005cited by this paper
• The extreme male brain theory of autism.

  2002cited by this paper
• Foetal testosterone and eye contact in 12-month-old human infants

  2002cited by this paper
• The "Reading the Mind in the Eyes" Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism.

  2001cited by this paper
• The oxytocin receptor system: structure, function, and regulation.

  2001cited by this paper
• The 2nd:4th digit ratio, sexual dimorphism, population differences, and reproductive success. evidence for sexually antagonistic genes?

  2000cited by this paper
• Nature, Nurture, and Individual Differences in Early Understanding of Mind

  1999cited by this paper
• Heritability of social cognitive skills in children and adolescents

  1999cited by this paper
• Interacting minds--a biological basis.

  1999cited by this paper
• Effect of oxytocin on testosterone production by isolated rat Leydig cells is mediated via a specific oxytocin receptor.

  1995cited by this paper
• Structural organization of the human oxytocin receptor gene.

  1994cited by this paper
• Gonadal steroids regulate oxytocin receptors but not vasopressin receptors in the brain of male and female rats. An autoradiographical study.

  1990cited by this paper
• Social Psychological and Personality Science on Behalf Of: Society for Personality and Social Psychology Association for Research in Personality European Association of Social Psychology Society of Experimental and Social Psychology

  year unknowncited by this paper

• Reading the Mind in the Eyes Test Scores Demonstrate Poor Structural Properties in Nine Large Non-Clinical Samples

  2025cites this paper
• Assessing social cognition in patients with schizophrenia and healthy controls using the reading the mind in the eyes test (RMET): a systematic review and meta-regression.

  2024cites this paper
• Polymorphisms in Oxytocin and Vasopressin Receptor Genes as a Factor Shaping the Clinical Picture and the Risk of ASD in Males

  2023cites this paper
• Gender differences in empathy and clinical symptoms in chronic schizophrenia patients: a large sample study based on a Chinese Han population

  2023cites this paper
• The Interaction Between POMC rs2071345 Polymorphism and Alcohol Dependence in Anxiety Symptoms Among Chinese Male Problem Drinkers

  2022cites this paper
• Reading language of the eyes.

  2022cites this paper
• Use of crowdsourced images for determining 2D:4D and relationship to pro-environmental variables

  2022cites this paper
• No evidence for altered prenatal exposure to testosterone in young females diagnosed with Borderline Personality Disorder

  2022cites this paper
• Physical activity associates empathy in Japanese young adults with specific gene variations of oxytocin receptor and vasopressin V1B receptor.

  2022cites this paper
• The influence of rs53576 polymorphism in the oxytocin receptor (OXTR) gene on empathy in healthy adults by subtype and ethnicity: a systematic review and meta-analysis

  2021cites this paper
• Entrepreneurial intentions: the relevance of nature and nurture

  2021cites this paper
• No links between genetic variation and developing theory of mind: A preregistered replication attempt of candidate gene studies.

  2021cites this paper
• Adrenocortical attunement, reactivity, and potential genetic correlates among parent-daughter dyads from low-income families.

  2020cites this paper
• The role of schizotypal traits and the OXTR gene in theory of mind in schizophrenia: A family-based study

  2020cites this paper
• Burnout in university faculty: An interaction between subjective sleep quality and the OXTR rs2268498 polymorphism.

  2020cites this paper
• Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups

  2020influential citation
• A variation in the infant oxytocin receptor gene modulates infant hippocampal volumes in association with sex and prenatal maternal anxiety.

  2020cites this paper
• Gene X Environment Interactions and Pillow Talk: Investigating the Associations among the OXTR Gene, Orgasm, Post Sex Communication, and Relationship Satisfaction in Young Adult Relationships

  2020cites this paper
• The relation between oxytocin receptor gene polymorphisms, adult attachment and Instagram sociability: An exploratory analysis

  2020cites this paper
• Genetic and peripheral markers of the oxytocin system and parental care jointly support the cross-generational transmission of bonding across three generations.

  2019cites this paper
• The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism

  2019influential citation
• OXTR rs53576 polymorphism impacts interpersonal adaptability: Dispositional forgiveness as a mediator.

  2019cites this paper
• What Do You Have in Mind? Measures to Assess Mental State Reasoning in Neuropsychiatric Populations

  2019cites this paper
• Heterogeneity of research results: New perspectives on psychological science

  2019cites this paper
• Index

  2018cites this paper
• Oxytocin and Vasopressin Receptor variants as a window onto the evolution of human prosociality

  2018cites this paper
• Second to fourth digit ratio (2D:4D), tomboyism, and temperament

  2018cites this paper
• Affectionate Communication in Close Relationships

  2018cites this paper
• Genetic Determinants of Empathy. Research perspectives derived from a comprehensive research review and from the analysis of a study associating dispositional emotional empathy with a common oxytocin receptor polymorphism

  2018cites this paper
• Endnotes

  2018cites this paper
• An Introduction to Affectionate Communication

  2018cites this paper
• Preface

  2018cites this paper
• Communicating Affection in Various Relationships

  2018cites this paper
• References

  2018cites this paper
• Decoding and Responding to Affectionate Messages

  2018cites this paper
• Affectionate Communication and Mental Wellness

  2018cites this paper
• Affectionate Communication and Physical Health

  2018cites this paper
• Predicting Affectionate Behavior

  2018cites this paper
• Encoding and Measuring Affectionate Messages

  2018cites this paper
• Associations between neurochemical receptor genes, 2D:4D, impulsivity and relationship quality

  2018cites this paper
• Looking Back and Looking Ahead

  2018cites this paper
• Oxytocin Enhancement of Emotional Empathy: Generalization Across Cultures and Effects on Amygdala Activity

  2018cites this paper
• The OXTR Single-Nucleotide Polymorphism rs53576 Moderates the Impact of Childhood Maltreatment on Empathy for Social Pain in Female Participants: Evidence for Differential Susceptibility

  2018cites this paper
• A Review of Oxytocin and Arginine-Vasopressin Receptors and Their Modulation of Autism Spectrum Disorder

  2018influential citation
• Oxytocin and Interpersonal Relationships.

  2018cites this paper
• Thinking about Affection

  2018cites this paper
• The Dark Side of Affectionate Communication

  2018cites this paper
• Birth weight interacts with a functional variant of the oxytocin receptor gene (OXTR) to predict executive functioning in children

  2017cites this paper
• Chapter 9 Behavior genetics of prosocial behavior

  2017cites this paper
• Something to talk about: Gossip increases oxytocin levels in a near real-life situation.

  2017cites this paper
• Genes Related to Oxytocin and Arginine-Vasopressin Pathways: Associations with Autism Spectrum Disorders

  2017cites this paper
• OXTR polymorphism in depression and completed suicide-A study on a large population sample.

  2017cites this paper
• Revisiting the impact of OXTR rs53576 on empathy: A population-based study and a meta-analysis.

  2017cites this paper
• Endogenous Testosterone and Exogenous Oxytocin Modulate Attentional Processing of Infant Faces

  2016cites this paper
• Delay discounting, genetic sensitivity, and leukocyte telomere length

  2016cites this paper
• The Effects of Exogenous Testosterone on Men’s Moral Decision-Making

  2016cites this paper
• Oxytocin: Biomarker of Affiliation and Neurodevelopment in Premature Infants

  2016cites this paper
• Strong but flexible: How fundamental social motives support but sometimes also thwart favorable attractiveness biases

  2016cites this paper
• The endocrinology of human caregiving and its intergenerational transmission

  2016cites this paper
• Oxytocin Pathway Genes: Evolutionary Ancient System Impacting on Human Affiliation, Sociality, and Psychopathology.

  2016cites this paper
• Polymorphisms of two loci at the oxytocin receptor gene in populations of Africa, Asia and South Europe

  2016cites this paper