Vagus nerve stimulation mitigates intrinsic cardiac neuronal remodeling and cardiac hypertrophy induced by chronic pressure overload in guinea pig.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  American Journal of Physiology. Heart and Circulatory Physiology

• Publication date

  2016-05-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1152/ajpheart.00939.2015PMID 26993230PMCID PMC4895835
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Extended Follow-Up of Patients With Heart Failure Receiving Autonomic Regulation Therapy in the ANTHEM-HF Study.

  2016cited by this paper
• Myocardial infarction induces structural and functional remodelling of the intrinsic cardiac nervous system

  2016cited by this paper
• Vagus nerve stimulation mitigates intrinsic cardiac neuronal and adverse myocyte remodeling postmyocardial infarction.

  2015cited by this paper
• Remodeling of stellate ganglion neurons after spatially targeted myocardial infarction: Neuropeptide and morphologic changes.

  2015cited by this paper
• Autonomic Regulation Therapy in Heart Failure

  2015cited by this paper
• Angiotensin receptors alter myocardial infarction-induced remodeling of the guinea pig cardiac plexus.

  2015cited by this paper
• Cardiac innervation and sudden cardiac death.

  2015cited by this paper
• Vagal nerve stimulation activates vagal afferent fibers that reduce cardiac efferent parasympathetic effects.

  2015cited by this paper
• Novel Interventional Therapies to Modulate the Autonomic Tone in Heart Failure.

  2015cited by this paper
• Antiarrhythmic therapy in 2014: Contemporary approaches to treating arrhythmias

  2015cited by this paper
• Central-peripheral neural network interactions evoked by vagus nerve stimulation: functional consequences on control of cardiac function.

  2015cited by this paper
• The autonomic nervous system and heart failure.

  2014influential reference
• Cardiac Sympathetic Afferent Denervation Attenuates Cardiac Remodeling and Improves Cardiovascular Dysfunction in Rats With Heart Failure

  2014cited by this paper
• Cardiac sympathetic denervation in patients with refractory ventricular arrhythmias or electrical storm: intermediate and long-term follow-up.

  2014cited by this paper
• Heart Failure With Preserved Ejection Fraction

  2014cited by this paper
• Electrophysiological effects of right and left vagal nerve stimulation on the ventricular myocardium.

  2014cited by this paper
• Heart failure with preserved ejection fraction

  2014cited by this paper
• Dynamic remodeling of the guinea pig intrinsic cardiac plexus induced by chronic myocardial infarction.

  2014cited by this paper
• Network interactions within the canine intrinsic cardiac nervous system: implications for reflex control of regional cardiac function

  2013cited by this paper
• Functional differences between junctional and extrajunctional adrenergic receptor activation in mammalian ventricle.

  2013cited by this paper
• Myths and realities of the cardiac vagus

  2013cited by this paper
• Dynamic neural networking as a basis for plasticity in the control of heart rate.

  2013cited by this paper
• Low-amplitude, left vagus nerve stimulation significantly attenuates ventricular dysfunction and infarct size through prevention of mitochondrial dysfunction during acute ischemia-reperfusion injury.

  2013cited by this paper
• Neural control hierarchy of the heart has not evolved to deal with myocardial ischemia.

  2013cited by this paper
• Vagus nerve stimulation: from epilepsy to the cholinergic anti‐inflammatory pathway

  2013cited by this paper
• Remodeling of intrinsic cardiac neurons: effects of β-adrenergic receptor blockade in guinea pig models of chronic heart disease.

  2012cited by this paper
• Animal models of heart failure: a scientific statement from the American Heart Association.

  2012cited by this paper
• Functional Neuroanatomy and Sleep‐Disordered Breathing: Implications for Autonomic Regulation

  2012cited by this paper
• Neurohumoral stimulation.

  2012cited by this paper
• Translational success stories: angiotensin receptor 1 antagonists in heart failure.

  2011cited by this paper
• Chronic vagus nerve stimulation: a new and promising therapeutic approach for chronic heart failure.

  2011cited by this paper
• Global and regional putamen volume loss in patients with heart failure

  2011cited by this paper
• Neural control of heart rate: the role of neuronal networking.

  2011cited by this paper
• Evidence for impaired vagus nerve activity in heart failure

  2011cited by this paper
• Remodeling of the guinea pig intrinsic cardiac plexus with chronic pressure overload.

  2009cited by this paper
• Localization of multiple neurotransmitters in surgically derived specimens of human atrial ganglia.

  2009cited by this paper
• Dorsal spinal cord stimulation obtunds the capacity of intrathoracic extracardiac neurons to transduce myocardial ischemia

  2009cited by this paper
• Spatially divergent cardiac responses to nicotinic stimulation of ganglionated plexus neurons in the canine heart.

  2009cited by this paper
• Potential clinical relevance of the ‘little brain’ on the mammalian heart

  2008cited by this paper
• Stochastic behavior of atrial and ventricular intrinsic cardiac neurons.

  2006cited by this paper
• Myocardial substrate metabolism in the normal and failing heart.

  2005influential reference
• Mammalian Cardiac Ganglia as Local Integration Centers: Histochemical and Electrophysiological Evidence

  2004influential reference
• Basic and clinical neurocardiology

  2004cited by this paper
• Electrophysical properties of intrainsic cardiac neurons

  2004cited by this paper
• Electrophysiological properties of intrinsic cardiac neurons: the foundation of neurocardiology

  2004cited by this paper
• Interactions within the intrinsic cardiac nervous system contribute to chronotropic regulation.

  2003cited by this paper
• Muscarinic and nicotinic ACh receptor activation differentially mobilize Ca2+ in rat intracardiac ganglion neurons.

  2003cited by this paper
• Akt and PI 3-Kinase Signaling in Cardiomyocyte Hypertrophy and Survival

  2003cited by this paper
• Pathology of intrinsic cardiac neurons from ischemic human hearts

  2000cited by this paper
• New insights into sympathetic regulation of glucose and fat metabolism

  2000cited by this paper
• Modulation of intrinsic cardiac neurons by spinal cord stimulation: implications for its therapeutic use in angina pectoris.

  2000cited by this paper
• Functional interdependence of neurons in a single canine intrinsic cardiac ganglionated plexus

  2000cited by this paper
• Autonomic interactions for control of atrial rate are maintained after SA nodal parasympathectomy.

  1997cited by this paper
• Innervation of the liver and glucoregulation: roles of the hypothalamus and autonomic nerves.

  1996cited by this paper
• Parasympathetic inhibition of sympathetic effects on sinus rate in anesthetized dogs.

  1996cited by this paper
• Evidence for afferent fiber innervation of parasympathetic neurons of the guinea-pig cardiac ganglion.

  1995cited by this paper
• M1 and M2 muscarinic receptors mediate excitation and inhibition of guinea‐pig intracardiac neurones in culture.

  1990cited by this paper
• Differential sympathetic regulation of automatic, conductile, and contractile tissue in dog heart.

  1988cited by this paper
• Selective vagal innervation of sinoatrial and atrioventricular nodes in canine heart.

  1986cited by this paper
• Neural Control of the Heart

  1984cited by this paper
• Sympathetic-parasympathetic interactions in the heart.

  1971cited by this paper

• Biophysical modelling of intrinsic cardiac nervous system neuronal electrophysiology based on single‐cell transcriptomics

  2025cites this paper
• Vagus nerve stimulation alleviates cardiac dysfunction and inflammatory markers during heart failure in rats.

  2024cites this paper
• Emerging optogenetics technologies in biomedical applications

  2023cites this paper
• Vagus Nerve Stimulation and Inflammation in Cardiovascular Disease: A State‐of‐the‐Art Review

  2023cites this paper
• Vagus Nerve Stimulation for Cardiovascular Diseases: Is There Light at the End of the Tunnel?

  2023cites this paper
• Vagal Nerve Stimulation Reduces Ventricular Arrhythmias and Mitigates Adverse Neural Cardiac Remodeling Post–Myocardial Infarction

  2023cites this paper
• Vagus nerve stimulation parameters evoke differential neuronal responses in the locus coeruleus

  2023cites this paper
• Autonomic nervous system and cardiac neuro-signaling pathway modulation in cardiovascular disorders and Alzheimer’s disease

  2023cites this paper
• The vagus nerve in cardiovascular physiology and pathophysiology: From evolutionary insights to clinical medicine.

  2023cites this paper
• Closed-loop modeling of central and intrinsic cardiac nervous system circuits underlying cardiovascular control.

  2023cites this paper
• Development of neuromodulation for atrial fibrillation: a narrative review

  2023cites this paper
• Vagus Nerve Stimulation and Atrial Fibrillation: Revealing the Paradox.

  2022cites this paper
• Non-Pharmacologic Autonomic Neuromodulation for Treatment of Heart Failure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  2022cites this paper
• Transcutaneous Vagus Nerve Stimulation Ameliorates the Phenotype of Heart Failure With Preserved Ejection Fraction Through Its Anti-Inflammatory Effects

  2022cites this paper
• Morphotopographic characteristics of the extrinsic innervation of the heart in guinea pigs (Cavia porcellus).

  2022cites this paper
• Autonomic regulation device therapy in patients with heart failure with preserved ejection fraction

  2021cites this paper
• Optical vagus nerve modulation of heart and respiration via heart-injected retrograde AAV

  2021cites this paper
• Development and characterization of a chronic implant mouse model for vagus nerve stimulation

  2021cites this paper
• Benefits of pharmacological and electrical cholinergic stimulation in hypertension and heart failure

  2021cites this paper
• Neuroscientific Therapies for Atrial Fibrillation.

  2021cites this paper
• Vagus nerve stimulation activates nucleus of solitary tract neurons via supramedullary pathways

  2021cites this paper
• Vagal Neuromodulation in Chronic Heart Failure With Reduced Ejection Fraction: A Systematic Review and Meta-Analysis

  2021cites this paper
• Selective Modulation of Heart and Respiration by Optical Control of Vagus Nerve Axons Innervating the Heart

  2020cites this paper
• An implant for long-term cervical vagus nerve stimulation in mice

  2020cites this paper
• Non-invasive vagus nerve stimulation attenuates proinflammatory cytokines and augments antioxidant levels in the brainstem and forebrain regions of Dahl salt sensitive rats

  2020cites this paper
• Evidence of structural and functional plasticity occurring within the intracardiac nervous system of spontaneously hypertensive rats.

  2020cites this paper
• Autonomic Modulation for Cardiovascular Disease

  2020cites this paper
• Vagus nerve stimulation optimized cardiomyocyte phenotype, sarcomere organization and energy metabolism in infarcted heart through FoxO3A-VEGF signaling

  2020cites this paper
• Vagus nerve stimulation for the treatment of heart failure

  2019cites this paper
• Hype or hope: Vagus nerve stimulation against acute myocardial ischemia-reperfusion injury.

  2019cites this paper
• Autonomic Neuromodulation Acutely Ameliorates Left Ventricular Strain in Humans

  2018cites this paper
• Low‐level transcutaneous vagus nerve stimulation attenuates cardiac remodelling in a rat model of heart failure with preserved ejection fraction

  2018cites this paper
• Calming the Nervous Heart: Autonomic Therapies in Heart Failure.

  2018cites this paper
• Effects of vagus nerve stimulation on ventricular electrophysiology and nitric oxide release

  2018cites this paper
• Foundational concepts for cardiac neuromodulation

  2018cites this paper
• Autonomic Nervous System and Neurocardiac Physiopathology

  2018cites this paper
• Chapter 3 Autonomic Nervous System and Neurocardiac Physiopathology

  2018cites this paper
• Defining the neural fulcrum for chronic vagus nerve stimulation: implications for integrated cardiac control

  2017cites this paper
• Cervical vagus nerve stimulation augments spontaneous discharge in second- and higher-order sensory neurons in the rat nucleus of the solitary tract.

  2017cites this paper
• From drugs to devices and back again: chemical vagal nerve stimulation for the treatment of heart failure.

  2017cites this paper
• Thoracic spinal cord and cervical vagosympathetic neuromodulation obtund nodose sensory transduction of myocardial ischemia.

  2017cites this paper
• Heart-Brain Axis: Effects of Neurologic Injury on Cardiovascular Function.

  2017cites this paper
• Aberrant fecal flora observed in guinea pigs with pressure overload is mitigated in animals receiving vagus nerve stimulation therapy.

  2016cites this paper