Branch-point stoichiometry can generate weak links in metabolism: the case of glycine biosynthesis

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Biosciences

• Publication date

  2008-11-13

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s12038-008-0097-5PMID 19179765
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• What history tells us XV. Cyril Norman Hinshelwood (1897–1967) — A chemical dynamic vision of the organic world

  2008cited by this paper
• Towards philosophical foundations of Systems Biology: introduction

  2007cited by this paper
• Systems Biology: Philosophical Foundations

  2007cited by this paper
• Glycine turnover and decarboxylation rate quantified in healthy men and women using primed, constant infusions of [1,2-(13)C2]glycine and [(2)H3]leucine.

  2007cited by this paper
• The fluxes through glycolytic enzymes in Saccharomyces cerevisiae are predominantly regulated at posttranscriptional levels

  2007cited by this paper
• The elephant knee joint: morphological and biomechanical considerations

  2006cited by this paper
• Putting the Systems Back into Systems Biology

  2006cited by this paper
• Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals.

  2006cited by this paper
• Comparative nutrition and metabolism: explication of open questions with emphasis on protein and amino acids.

  2005cited by this paper
• Serine hydroxymethyltransferase revisited.

  2005cited by this paper
• Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply.

  2005cited by this paper
• The pursuit of perfection

  2004cited by this paper
• L-serine in disease and development.

  2003cited by this paper
• Endogenous glycine and tyrosine production is maintained in adults consuming a marginal-protein diet.

  2002cited by this paper
• [Glycine: a cell-protecting anti-oxidant nutrient].

  2002cited by this paper
• What does it take to be C4? Lessons from the evolution of C4 photosynthesis.

  2001cited by this paper
• What Does It Take to Be C 4 ? Lessons from the Evolution of C 4 Photosynthesis

  2001cited by this paper
• Information transfer in metabolic pathways. Effects of irreversible steps in computer models.

  2001cited by this paper
• Information transfer in metabolic pathways

  2001cited by this paper
• Regulating the cellular economy of supply and demand

  2000cited by this paper
• Degenerative joint disease in African great apes: an evolutionary perspective.

  2000cited by this paper
• Flux of the l-Serine Metabolism in Rabbit, Human, and Dog Livers

  1999cited by this paper
• Beneficial effects of L‐serine and glycine in the management of seizures in 3‐phosphoglycerate dehydrogenase deficiency

  1998cited by this paper
• Network organization of cell metabolism: monosaccharide interconversion.

  1997cited by this paper
• Theoretical approaches to the evolutionary optimization of glycolysis: thermodynamic and kinetic constraints.

  1997cited by this paper
• The puzzle of the Krebs citric acid cycle: Assembling the pieces of chemically feasible reactions, and opportunism in the design of metabolic pathways during evolution

  1996cited by this paper
• Understanding the Control of Metabolism

  1996cited by this paper
• Urinary excretion of 5-L-oxoproline (pyroglutamic acid) is increased during recovery from severe childhood malnutrition and responds to supplemental glycine.

  1996cited by this paper
• Urinary excretion of 5-L-oxoproline (pyroglutamic acid) is increased in normal adults consuming vegetarian or low protein diets.

  1996cited by this paper
• New evidence of temporomandibular arthrosis in human fossils from the middle pleistocene site of Atapuerca/Ibeas, Burgos, Spain

  1995cited by this paper
• Responses of metabolic systems to large changes in enzyme activities and effectors. 2. The linear treatment of branched pathways and metabolite concentrations. Assessment of the general non-linear case.

  1993cited by this paper
• Paleopathology Disease in the Fossil Record

  1992cited by this paper
• The glycine story.

  1991cited by this paper
• [The rhinoceros horn syndrome (an unusual form of neuropathy and arthrosis of the feet)].

  1987cited by this paper
• The rhinoceros horn syndrome (an unusual form of neuropathy and arthrosis of the feet)

  1987cited by this paper
• Diffuse idiopathic skeletal hyperostosis as reflected in the paleontologic record: dinosaurs and early mammals.

  1987cited by this paper
• On Parts and Wholes in Metabolism

  1986cited by this paper
• The Organization of Cell Metabolism

  1986cited by this paper
• Interorgan amino acid nutrition.

  1982cited by this paper
• Fibroblasts degrade newly synthesised collagen within the cell before secretion

  1978cited by this paper
• Evolution and tinkering.

  1977cited by this paper
• Significance of formate as an intermediate in the oxidation of the methionine, S-methyl-L-cysteine and sarcosine methyl carbons to CO2 in the rat.

  1977cited by this paper
• Osteoarthritis in Selected Wild Mammals

  1977cited by this paper
• Degenerative arthritis in a black rhinoceros.

  1967cited by this paper
• Degenerative arthritis in a black rhinoceros.

  1967cited by this paper
• Pathology and the Posture of Neanderthal Man

  1957cited by this paper
• Anthropology Today: An Encyclopedic Inventory

  1953cited by this paper

• An Innovative Enzymatic Surface Plasmon Resonance-Based Biosensor Designed for Precise Detection of Glycine Amino Acid

  2025cites this paper
• Amino acid metabolism in kidney health and disease

  2024cites this paper
• Distinct genomic routes underlie transitions to specialised symbiotic lifestyles in deep-sea annelid worms

  2023cites this paper
• Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media

  2023cites this paper
• Control analysis of collagen synthesis by glycine, proline and lysine in bovine chondrocytes in vitro - Its relevance for medicine and nutrition

  2023cites this paper
• Is It Time to Reconsider the U.S. Recommendations for Dietary Protein and Amino Acid Intake?

  2023cites this paper
• Effect of Different Collagen on Anterior Cruciate Ligament Transection and Medial Meniscectomy-Induced Osteoarthritis Male Rats

  2022cites this paper
• Injectable adhesive self-healing biocompatible hydrogel for haemostasis, wound healing, and postoperative tissue adhesion prevention in nephron-sparing surgery.

  2022cites this paper
• The hologenome of Osedax frankpressi reveals the genetic interplay for the symbiotic digestion of vertebrate bone

  2022cites this paper
• Biosynthetic approaches to efficient assimilation of CO2 via photorespiration modification in plant chassis

  2022cites this paper
• De Novo Glycine Synthesis Is Reduced in Adults With Morbid Obesity and Increases Following Bariatric Surgery

  2022cites this paper
• Phytochemicals: “A Small Defensive Advantage for Plants and Fungi; A Great Remedy for the Health of Mankind”

  2021cites this paper
• Glycine can prevent and fight virus invasiveness by reinforcing the extracellular matrix

  2021cites this paper
• One-carbon metabolism in cancer cells: a critical review based on a core model of central metabolism.

  2021cites this paper
• The role of energy, serine, glycine, and 1-carbon units in the cost of nitrogen excretion in mammals and birds.

  2021cites this paper
• Implications of excreta uric acid concentrations in broilers offered reduced-crude protein diets and dietary glycine requirements for uric acid synthesis

  2021cites this paper
• Impact of Bovine Diet on Metabolomic Profile of Skim Milk and Whey Protein Ingredients

  2019cites this paper
• Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases

  2019cites this paper
• Extended Utilization of Constraint-Based Metabolic Model in a Long-Growing Crop

  2019cites this paper
• High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis

  2018cites this paper
• Whole body creatine and protein kinetics in healthy men and women: effects of creatine and amino acid supplementation

  2016cites this paper
• Development of an integrated metabolic analysis toolbox

  2016cites this paper
• Division of labour: how does folate metabolism partition between one-carbon metabolism and amino acid oxidation?

  2015cites this paper
• Biochemistry and evolutionary biology: Two disciplines

  2014cites this paper
• Biochemistry and evolutionary biology: Two disciplines that need each other

  2014cites this paper
• Supply-demand analysis a framework for exploring the regulatory design of metabolism.

  2011cites this paper
• A weak link in metabolism : the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis

  2009cites this paper
• A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis

  2009cites this paper