Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  International Immunology

• Publication date

  1994-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/INTIMM/6.2.277PMID 7512374
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Thymus epithelium induces tissue-specific tolerance

  1993cited by this paper
• Immunological consequences of T cell-specific expression of H-2Kb molecules in transgenic mice.

  1993cited by this paper
• Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

  1993cited by this paper
• Inefficient positive selection of T cells directed by haematopoietic cells

  1992cited by this paper
• Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line

  1992cited by this paper
• Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

  1992cited by this paper
• Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny

  1992cited by this paper
• Autoimmune diabetes as a consequence of locally produced interleukin-2

  1992cited by this paper
• Studies on T cell maturation on defined thymic stromal cell populations in vitro

  1992cited by this paper
• Role of CD3 delta in surface expression of the TCR/CD3 complex and in activation for killing analyzed with a CD3 delta-negative cytotoxic T lymphocyte variant.

  1992cited by this paper
• Thymocytes can tolerize thymocytes by clonal deletion in vitro.

  1992cited by this paper
• Tolerance induction by thymic medullary epithelium.

  1992cited by this paper
• Organ injury associated with extrathymic induction of immune tolerance in doubly transgenic mice.

  1992cited by this paper
• Expression of major histocompatibility complex class I antigens at low levels in the thymus induces T cell tolerance via a non‐deletional mechanism

  1992cited by this paper
• Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen.

  1992cited by this paper
• Peripheral tolerance through clonal deletion of mature CD4-CD8+ T cells.

  1992cited by this paper
• Tolerance and MHC restriction in transgenic mice expressing a MHC class I gene in erythroid cells.

  1992cited by this paper
• Each of the two productive T cell receptor alpha-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an alpha chain which can contribute to the constitution of a surface-expressed alpha beta dimer.

  1991cited by this paper
• Transgenic mice carrying the guinea-pig alpha-lactalbumin gene transcribe milk protein genes in their sebaceous glands during lactation.

  1991cited by this paper
• Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.

  1991cited by this paper
• Non‐Deletional Mechanisms of Peripheral and Central Tolerance: Studies with Transgenic Mice with Tissue‐Specific Expression of a Foreign MHC Class I Antigen

  1991cited by this paper
• An unusual lineage of alpha/beta T cells that contains autoreactive cells

  1991cited by this paper
• Does T-cell tolerance require a dedicated antigen-presenting cell?

  1989cited by this paper
• Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

  1988cited by this paper
• Positive and negative selection of an antigen receptor on T cells in transgenic mice

  1988cited by this paper
• Split tolerance induced by the intrathymic adoptive transfer of thymocyte stem cells

  1988cited by this paper
• T cell tolerance by clonal elimination in the thymus.

  1987cited by this paper
• Monoclonal antibodies against murine gamma interferon.

  1984cited by this paper

• Subsets Suppresses T Cell Clonal Expansion Dioxygenase Expression in Dendritic Cell Cutting Edge: Induced Indoleamine 2,3

  2013cites this paper
• Islet Allografts to T Cell-Mediated Rejection Differential Susceptibility of Heart, Skin, and

  2013cites this paper
• Selection of T‐cell receptors with a recurrent CDR3β peptide‐contact motif within the repertoire of alloreactive CD8+ T cells

  2011cites this paper
• Alpha-1,2-Mannosidase and Hence N-Glycosylation Are Required for Regulatory T Cell Migration and Allograft Tolerance in Mice

  2010cites this paper
• Regulatory T cells can prevent memory CD8+ T-cell-mediated rejection following polymorphonuclear cell depletion

  2010cites this paper
• Anti-OX40 Prevents Effector T-Cell Accumulation and CD8+ T-Cell Mediated Skin Allograft Rejection

  2010cites this paper
• Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells.

  2008cites this paper
• A Rapid Method for Skin Grafting in Mice That Greatly Enhances Graft and Recipient Survival

  2007cites this paper
• Allograft rejection mediated by memory T cells is resistant to regulation

  2007cites this paper
• Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus.

  2007cites this paper
• This information is current as T Cell Help + Independently of CD 4 Generated in Response to Alloantigen T Cells Can Be + Effector and Memory CD 8

  2006cites this paper
• Role for Regulatory T Cells Tolerance in Molecular Chimeras: A Possible Induction of Alloreactive CD4 T Cell

  2006cites this paper
• Induction of Alloreactive CD4 T Cell Tolerance in Molecular Chimeras: A Possible Role for Regulatory T Cells1

  2006cites this paper
• Effector and Memory CD8+ T Cells Can Be Generated in Response to Alloantigen Independently of CD4+ T Cell Help1

  2006cites this paper
• The src Homology 2 Domain-Containing Tyrosine Phosphatase 2 Regulates Primary T-Dependent Immune Responses and Th Cell Differentiation1

  2005influential citation
• CD4+ CD25+ Regulatory T Cell Repertoire Formation in Response to Varying Expression of a neo-Self-Antigen 1

  2004cites this paper
• Dependency of Direct Pathway CD4+ T Cells on CD40-CD154 Costimulation Is Determined by Nature and Microenvironment of Primary Contact with Alloantigen1

  2004cites this paper
• Expression of a neo-Self-Antigen Formation in Response to Varying Regulatory T Cell Repertoire + CD 25 + CD 4

  2004cites this paper
• Induction of Central Tolerance by Mature T Cells1

  2004cites this paper
• CD4 CD25 Regulatory T Cell Repertoire Formation in Response to Varying Expression of a neo-Self-Antigen

  2004cites this paper
• Cutting Edge: Induced Indoleamine 2,3 Dioxygenase Expression in Dendritic Cell Subsets Suppresses T Cell Clonal Expansion1

  2003cites this paper
• Syngeneic bone marrow transduced with a recombinant retroviral vector to express endoplasmic reticulum signal-sequence-deleted major histocompatibility complex class-I alloantigen can induce specific immunologic unresponsiveness in vivo

  2003cites this paper
• Induction of Central Deletional T Cell Tolerance by Gene Therapy1

  2002influential citation
• Cutting Edge: CD4+CD25+ Alloantigen-Specific Immunoregulatory Cells That Can Prevent CD8+ T Cell-Mediated Graft Rejection: Implications for Anti-CD154 Immunotherapy1

  2002cites this paper
• Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

  2002cites this paper
• This information is current as Tolerance by Gene Therapy Induction of Central Deletional T Cell

  2002influential citation
• Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

  2002cites this paper
• Alloantigen-Specific Immunoregulatory Cells + CD 25 + Cutting Edge : CD 4

  2002cites this paper
• Differential Susceptibility of Heart, Skin, and Islet Allografts to T Cell-Mediated Rejection1

  2001cites this paper
• Differential Survival of Naive CD4 and CD8 T Cells1

  2000cites this paper
• Mechanisms of tolerance induction after intrathymic islet injection: determination of the fate of alloreactive thymocytes.

  1999cites this paper
• Greatly reduced efficiency of both positive and negative selection of thymocytes in CD45 tyrosine phosphatase‐deficient mice

  1999cites this paper
• T-cell activation, proliferation, and memory after cardiac transplantation in vivo.

  1999cites this paper
• T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms.

  1999cites this paper
• The visualization of T cell responses.

  1999cites this paper
• CD4 T Cell Tolerance to Human C-reactive Protein, an Inducible Serum Protein, Is Mediated by Medullary Thymic Epithelium

  1998cites this paper
• Co‐capping studies reveal CD8/TCR interactions after capping CD8β polypeptides and intracellular associations of CD8 with p56lck

  1998cites this paper
• Intrathymic administration of B cells induces prolonged survival of fully allogeneic cardiac grafts without prolonged deletion of donor-specific thymocytes.

  1998cites this paper
• Intrathymic expression of genes involved in organ specific autoimmune disease.

  1998cites this paper
• Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity.

  1998cites this paper
• Expanded cohorts of maternal CD8+ T-cells specific for paternal MHC class I accumulate during pregnancy.

  1998cites this paper
• The induction of transplantation tolerance by intrathymic (i.t.) delivery of alloantigen: a critical relationship between i.t. deletion, thymic export of new T cells and the timing of transplantation.

  1998cites this paper
• In vitro negative selection of viral superantigen-reactive thymocytes by thymic dendritic cells.

  1997cites this paper
• A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes.

  1997cites this paper
• Deletion of alloantigen‐reactive thymocytes as a mechanism of adult tolerance induction following intrathymic antigen administration

  1997cites this paper
• Thymic dendritic cells.

  1997cites this paper
• Thymic dendritic cells

  1997cites this paper
• Self major histocompatibility complex class I antigens expressed solely in lymphoid cells do not induce tolerance in the CD4+ T cell compartment

  1996cites this paper
• Medullary thymic epithelial cells induce tolerance to intracellular proteins.

  1996cites this paper
• Unprimed T cells are inefficiently stimulated by glycosylphosphatidylinositol-linked H-2Kb because of its lipid anchor rather than defects in CD8 binding.

  1996cites this paper
• Effects of different antigenic microenvironments on the course of CD8+ T cell responses in vivo.

  1996cites this paper
• Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function.

  1996cites this paper
• T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance.

  1994cites this paper
• Reprints Available Directly from the Publisher Photocopying Permitted by License Only Tolerance in Tcr/cognate Antigen Double-transgenic Mice Mediated by Incomplete Thymic Deletion and Peripheral Receptor Downregulation

  year unknowncites this paper