Early life trauma decreases glucocorticoid receptors in rat dentate gyrus upon adult re-stress: reversal by escitalopram.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Neuroscience

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.NEUROSCIENCE.2005.08.089PMID 16310967
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Comparison of the Effects of Citalopram and Escitalopram on 5-Ht-Mediated Neuroendocrine Responses

  2004cited by this paper
• R-citalopram inhibits functional and 5-HTP-evoked behavioural responses to the SSRI, escitalopram.

  2004cited by this paper
• Serotonin and Stress: Protective or Malevolent Actions in the Biobehavioral Response to Repeated Trauma?

  2004cited by this paper
• Anxiolytic-Like Effects of Escitalopram, Citalopram, and R-Citalopram in Maternally Separated Mouse Pups

  2004cited by this paper
• Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation.

  2004cited by this paper
• Expression microarray reproducibility is improved by optimising purification steps in RNA amplification and labelling

  2004cited by this paper
• Neuroimaging Abnormalities in the Amygdala in Mood Disorders

  2003cited by this paper
• Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities

  2003cited by this paper
• Endocrine, cognitive and hippocampal/cortical 5HT 1A/2A receptor changes evoked by a time-dependent sensitisation (TDS) stress model in rats.

  2003cited by this paper
• The effect of chronic fluoxetine treatment on brain corticosteroid receptor mRNA expression and spatial memory in young and aged rats.

  2002cited by this paper
• Neuroimaging findings in post-traumatic stress disorder

  2002cited by this paper
• Chronic psychosocial stress and concomitant repetitive transcranial magnetic stimulation: effects on stress hormone levels and adult hippocampal neurogenesis.

  2002cited by this paper
• Neuroimaging studies in post-traumatic stress disorder.

  2002cited by this paper
• The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies.

  2001cited by this paper
• Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine

  2001cited by this paper
• Chronic stress differentially regulates glucocorticoid negative feedback response in rats.

  2001cited by this paper
• Differential and Age‐Dependent Effects of Maternal Deprivation on the Hypothalamic‐Pituitary‐Adrenal Axis of Brown Norway Rats from Youth to Senescence

  2001cited by this paper
• Biology of posttraumatic stress disorder.

  2001cited by this paper
• Acute Stress-Induced Facilitation of the Hypothalamic-Pituitary-Adrenal Axis: Evidence for the Roles of Stressor Duration and Serotonin

  2001cited by this paper
• Acute-Stress-Induced Facilitation of the Hypothalamic-Pituitary-Adrenal Axis

  2000cited by this paper
• Effects of adverse experiences for brain structure and function.

  2000cited by this paper
• Selective effects on NGFI-A, MR, GR and NGFI-B hippocampal mRNA expression after chronic treatment with different subclasses of antidepressants in the rat

  2000cited by this paper
• Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

  2000cited by this paper
• The Effects of Serotonin on Glucocorticoid Receptor Binding in Rat Raphe Nuclei and Hippocampal Cells in Culture

  2000cited by this paper
• Effects of early adverse experiences on brain structure and function: clinical implications.

  2000cited by this paper
• Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus.

  2000cited by this paper
• Neonatal footshock stress alters adult behavior and hippocampal corticosteroid receptors.

  1999cited by this paper
• Stress and hippocampal plasticity.

  1999cited by this paper
• Clinical doses of fluoxetine and cerebral blood flow in healthy volunteers

  1999cited by this paper
• Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons.

  1999cited by this paper
• Serotonin and Stress

  1999cited by this paper
• Effect of clinical doses of fluoxetine on psychological variables in healthy volunteers.

  1998cited by this paper
• Novel therapeutic approaches beyond the serotonin receptor.

  1998cited by this paper
• Stress-restress: effects on ACTH and fast feedback.

  1997cited by this paper
• A molecular and cellular theory of depression.

  1997cited by this paper
• Regulation of glucocorticoid and mineralocorticoid receptor mRNAs in the hippocampus of the maternally deprived infant rat.

  1996cited by this paper
• The effect of chronic treatment with antidepressant drugs on the corticosteroid receptor levels in the rat hippocampus.

  1994cited by this paper
• Criteria for rationally evaluating animal models of posttraumatic stress disorder.

  1993cited by this paper
• Childhood parental loss and adult psychopathology in women. A twin study perspective.

  1992cited by this paper
• Antidepressants increase glucocorticoid and mineralocorticoid receptor mRNA expression in rat hippocampus in vivo.

  1992cited by this paper
• The antidepressants fluoxetine, idazoxan and phenelzine alter corticotropin-releasing hormone and tyrosine hydroxylase mRNA levels in rat brain: therapeutic implications.

  1992cited by this paper

• Neuroanatomical mapping of huntingtin-associated protein 1 across the rostral and caudal clusters of mouse raphe nuclei and its immunohistochemical relationships with serotonin

  2025cites this paper
• Effects of prolonged escitalopram administration on long-term potentiation within the hippocampal CA1 area in rats under predictable and unpredictable chronic mild stress

  2024cites this paper
• The protective effects of escitalopram on synaptic plasticity in the CA1 region of chronically stressed and non‐stressed male rats

  2022cites this paper
• Inhibition of Hippocampal Neurogenesis Starting in Adolescence Increases Anxiodepressive Behaviors Amid Stress

  2022cites this paper
• Adolescence Predatory Risk Alters Social Behaviors and Cognitive Ability and Central Oxytocin and Vasopressin Expression in Adult Brandt’s Voles

  2022cites this paper
• Escitalopram alters the hypothalamic OX system but does not affect its up-regulation induced by early-life stress in adult rats.

  2022cites this paper
• Environmental enrichment modulates HPA axis reprogramming in adult male rats exposed to early adolescent stress.

  2021cites this paper
• Fetal programming pathway from maternal mental health to infant cortisol functioning: The role of placental 11β-HSD2 mRNA expression.

  2021cites this paper
• Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response

  2020cites this paper
• Repeated stress exposure in mid-adolescence attenuates behavioral, noradrenergic, and epigenetic effects of trauma-like stress in early adult male rats

  2020cites this paper
• Translational Medicine Strategies in PTSD Drug Development

  2019cites this paper
• Early postnatal hypothalamic-pituitary-adrenal axis activity and reduced insulin sensitivity in adult rats

  2019cites this paper
• Prefrontal cortical trkB, glucocorticoids, and their interactions in stress and developmental contexts

  2018cites this paper
• Maternal separation blunted spatial memory formation independent of peripheral and hippocampal insulin content in young adult male rats

  2018cites this paper
• The effects of stress in early life and adolescence on posttraumatic stress disorder, depression, and anxiety symptomatology in adulthood

  2017cites this paper
• A role for CRH and HPA Activation in the Regulation of Plasticity Signaling, Neuroinflammation and Emotional/Mnesic Behavior Following Global Cerebral Ischemia in Rats

  2016cites this paper
• ACUTE & PERIOPERATIVE PAIN SECTION Original Research Articles Epigenetics and the Transition from Acute to

  2016cites this paper
• Long-term Behavioral and Neuroendocrine Consequences of Early Adversity (Juvenile Stressor Exposure), and the Buffering Effects of ‘Comfort’ Food.

  2016cites this paper
• 5-HT receptor-mediated modulation of granule cell inhibition after juvenile stress recovers after a second exposure to adult stress.

  2015cites this paper
• How postnatal insults may program development: studies in animal models.

  2015cites this paper
• Effects of stress early in gestation on hippocampal neurogenesis and glucocorticoid receptor density in pregnant rats.

  2015cites this paper
• Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females

  2015cites this paper
• Fluoxetine effects on molecular, cellular and behavioral endophenotypes of depression are driven by the living environment

  2015cites this paper
• Bifidobacteria exert strain‐specific effects on stress‐related behavior and physiology in BALB/c mice

  2014cites this paper
• Evidence of lasting dysregulation of neuroendocrine and HPA axis function following global cerebral ischemia in male rats and the effect of Antalarmin on plasma corticosterone level.

  2014cites this paper
• Puberty and adolescence as a time of vulnerability to stressors that alter neurobehavioral processes.

  2014influential citation
• Early adolescent stress alters behavior and the HPA axis response in male and female adult rats: the relevance of the nature and duration of the stressor.

  2014cites this paper
• Understanding somatic symptom disorder: the role of translational neuroscience.

  2013cites this paper
• Chronic Exposure to Light Reverses the Effect of Maternal Separation on Proteins in the Prefrontal Cortex

  2013cites this paper
• Antidepressant Treatment Outcome Depends on the Quality of the Living Environment: A Pre-Clinical Investigation in Mice

  2013cites this paper
• Animal models of schizophrenia: developmental preparation in rats.

  2013cites this paper
• Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala.

  2013influential citation
• Effects of developmental fluoxetine exposure on neurobehavioral outcomes

  2013cites this paper
• Treadmill exercise exerts ameliorating effect on isolation-induced depression via neuronal activation

  2013cites this paper
• Depression and the hypothalamic-pituitary-adrenal axis: increasing the scope

  2012cites this paper
• Behavioral changes after maternal separation are reversed by chronic constant light treatment.

  2012cites this paper
• Epigenetics and the transition from acute to chronic pain.

  2012cites this paper
• Metabotropic and ionotropic glutamate receptors as neurobiological targets in anxiety and stress-related disorders: focus on pharmacology and preclinical translational models.

  2012cites this paper
• Developmental fluoxetine exposure differentially alters central and peripheral measures of the HPA system in adolescent male and female offspring.

  2012cites this paper
• Intermittent physical stress during early- and mid-adolescence differentially alters rats' anxiety- and depression-like behaviors in adulthood.

  2012cites this paper
• Immediate and Enduring Effects of Corticosterone Administration During Adolescence and Adulthood on Anxiety and Depressive Behavior in Male Rats

  2011cites this paper
• Chronic restraint stress in adolescence differentially influences hypothalamic‐pituitary‐adrenal axis function and adult hippocampal neurogenesis in male and female rats

  2011cites this paper
• Dissociation of antidepressant-like activity of escitalopram and nortriptyline on behaviour and hippocampal BDNF expression in female rats

  2011cites this paper
• Depression and Alzheimer's Disease: Is Stress the Initiating Factor in a Common Neuropathological Cascade?

  2011cites this paper
• EXPOSURE TO STRESS DURING DEVELOPMENT AND THE IMPORTANCE OF TIMING: AN ANIMAL MODEL OF EARLY LIFE ADVERSITY

  2010cites this paper
• The potential of exercise to reverse stress induced abnormalities in the rat brain

  2010cites this paper
• Effects of escitalopram on stress-related relapses in women with multiple sclerosis: an open-label, randomized, controlled, one-year follow-up study.

  2010cites this paper
• Investigations of HPA function and the enduring consequences of stressors in adolescence in animal models.

  2010cites this paper
• Mixed‐Model QSAR at the Glucocorticoid Receptor: Predicting the Binding Mode and Affinity of Psychotropic Drugs

  2009cites this paper
• Deployment-related severe fatigue with depressive symptoms is associated with increased glucocorticoid binding to peripheral blood mononuclear cells.

  2009cites this paper
• Maternal separation alters nerve growth factor and corticosterone levels but not the DNA methylation status of the exon 17 glucocorticoid receptor promoter region

  2009cites this paper
• A proteomic analysis of the ventral hippocampus of rats subjected to maternal separation and escitalopram treatment

  2009cites this paper
• Stressors can affect immobility time and response to imipramine in the rat forced swim test.

  2009cites this paper
• Zukunftsstrategien für die Entdeckung neuer Antidepressiva

  2008cites this paper
• Differential Susceptibility to Extinction-Induced Despair and Age-Dependent Alterations in the Hypothalamic-Pituitary-Adrenal Axis and Neurochemical Parameters

  2008cites this paper
• Affective-related endophenotypes in serotonin transporter over-expressing mice

  2008cites this paper
• Escitalopram Regulates Expression of TRH and TRH-Like Peptides in Rat Brain and Peripheral Tissues

  2008cites this paper
• Stress hormones and immune function.

  2008cites this paper
• Large Scale Hippocampal Cellular Distress may Explain the Behavioral Consequences of Repetitive Traumatic Experiences-A Proteomic Approach

  2008cites this paper
• Extended characterisation and validation of an animal model of post-traumatic stress disorder : behavioural, molecular and pharmacological studies

  2007cites this paper
• Early maternal separation alters the response to traumatization: resulting in increased levels of hippocampal neurotrophic factors

  2007cites this paper
• Stress vulnerabilities in an animal model of post-traumatic stress disorder.

  2007cites this paper
• Escitalopram

  2006cites this paper
• Developmental Trauma is Associated with Behavioral Hyperarousal, Altered HPA Axis Activity, and Decreased Hippocampal Neurotrophin Expression in the Adult Rat

  2006cites this paper
• L'odeur de la peur : Neurobiologie du conditionnement de peur à l'odeur chez le rat adulte et conséquences à long-terme des expériences néonatales

  2006cites this paper
• The effects of early life trauma on the neurochemistry and behaviour of the adult rat

  2006cites this paper