Dose-dependent beneficial hemodynamic effects of BAY 41-2272 in a canine model of acute pulmonary thromboembolism.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  European Journal of Pharmacology

• Publication date

  2008-02-26

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/J.EJPHAR.2007.11.030PMID 18076875
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• EFFECT OF BAY 41‐2272 IN THE PULMONARY HYPERTENSION INDUCED BY HEPARIN–PROTAMINE COMPLEX IN ANAESTHETIZED DOGS

  2007cited by this paper
• A role for matrix metalloproteinase-9 in the hemodynamic changes following acute pulmonary embolism.

  2007cited by this paper
• Hemodynamic effects of sildenafil interaction with a nitric oxide donor compound in a dog model of acute pulmonary embolism.

  2006cited by this paper
• Low-dose intravenous nitrite improves hemodynamics in a canine model of acute pulmonary thromboembolism.

  2006cited by this paper
• Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels.

  2006cited by this paper
• Relationship between systemic nitric oxide metabolites and cyclic GMP in healthy male volunteers

  2006cited by this paper
• Activation of Soluble Guanylate Cyclase Reverses Experimental Pulmonary Hypertension and Vascular Remodeling

  2006cited by this paper
• NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

  2006cited by this paper
• l-Arginine attenuates acute pulmonary embolism-induced oxidative stress and pulmonary hypertension.

  2005cited by this paper
• Effects of BAY 41-2272, a soluble guanylate cyclase activator, on pulmonary vascular reactivity in the ovine fetus.

  2005cited by this paper
• Sildenafil selectively inhibits acute pulmonary embolism-induced pulmonary hypertension.

  2005cited by this paper
• Hemodynamic Benefits of Matrix Metalloproteinase-9 Inhibition by Doxycycline During Experimental Acute Pulmonary Embolism

  2005cited by this paper
• Hemodynamic effects of combined sildenafil and L-arginine during acute pulmonary embolism-induced pulmonary hypertension.

  2005cited by this paper
• The Effect of Sildenafil on Pulmonary Embolism-Induced Oxidative Stress and Pulmonary Hypertension

  2005cited by this paper
• Soluble Guanylate Cyclase Activator Reverses Acute Pulmonary Hypertension and Augments the Pulmonary Vasodilator Response to Inhaled Nitric Oxide in Awake Lambs

  2004cited by this paper
• Pulmonary embolism.

  2003cited by this paper
• Neurogenic and Humoral Vasoconstriction in Acute Pulmonary Thromboembolism

  2003cited by this paper
• Is There a Place for Inhaled Nitric Oxide in the Therapy of Acute Pulmonary Embolism?

  2002cited by this paper
• The effect of peroxynitrite on the catalytic activity of soluble guanylyl cyclase.

  2001cited by this paper
• Pathophysiology and treatment of haemodynamic instability in acute pulmonary embolism: the pivotal role of pulmonary vasoconstriction.

  2000cited by this paper
• The Hemodynamic Effects of Endothelin Receptor Antagonism During a Venous Air Infusion in Dogs

  2000cited by this paper
• Nonselective endothelin-receptor antagonism attenuates hemodynamic changes after massive pulmonary air embolism in dogs.

  2000cited by this paper
• Plasma cGMP levels in air embolism-induced acute lung injury.

  2000cited by this paper
• Small-dose inhaled nitric oxide attenuates hemodynamic changes after pulmonary air embolism in dogs.

  1999cited by this paper
• Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs

  1999cited by this paper
• Simple assay for the level of total lipid peroxides in serum or plasma.

  1998cited by this paper
• Pharmacologic hemodynamic support in massive pulmonary embolism.

  1997cited by this paper
• Inhaled nitric oxide selectively decreases pulmonary artery pressure and pulmonary vascular resistance following acute massive pulmonary microembolism in piglets.

  1996cited by this paper
• Regulation of pulmonary vascular tone.

  1995cited by this paper

• Non-mechanical haemodynamic support in acute pulmonary thromboembolism: a scoping review

  2025cites this paper
• Riociguat, sildenafil and inhaled nitric oxide reduces pulmonary vascular resistance and improves right ventricular function in a porcine model of acute pulmonary embolism

  2020cites this paper
• Pulmonary vasodilation in acute pulmonary embolism – a systematic review

  2019cites this paper
• Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.

  2019cites this paper
• Efficacy evaluation of reteplase in a novel canine acute pulmonary thromboembolism model developed by minimally invasive surgery and digital subtraction angiography

  2018influential citation
• Discovery and development of sGC stimulators for the treatment of pulmonary hypertension and rare diseases.

  2018cites this paper
• Soluble Guanylate Cyclase Stimulators and Activators: Novel Therapies for Pulmonary Vascular Disease or a Different Method of Increasing cGMP?

  2016cites this paper
• The soluble guanylyl cyclase activator BAY 60-2770 potently relaxes the pulmonary artery on congenital diaphragmatic hernia rabbit model

  2014cites this paper
• Nebivolol attenuates prooxidant and profibrotic mechanisms involving TGF-β and MMPs, and decreases vascular remodeling in renovascular hypertension.

  2013cites this paper
• Disease Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary

  2013cites this paper
• A soluble guanylate cyclase stimulator, BAY 41-8543, preserves right ventricular function in experimental pulmonary embolism.

  2013cites this paper
• Soluble guanylate cyclase stimulators in pulmonary hypertension.

  2013cites this paper
• Arginase depletes plasma l-arginine and decreases pulmonary vascular reserve during experimental pulmonary embolism.

  2012cites this paper
• Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension.

  2012cites this paper
• Matrix metalloproteinase-9 genetic variations affect MMP-9 levels in obese children

  2011cites this paper
• Metalloproteinase inhibition protects against cardiomyocyte injury during experimental acute pulmonary thromboembolism*

  2011cites this paper
• Pulmonary vascular reserve during experimental pulmonary embolism: Effects of a soluble guanylate cyclase stimulator, BAY 41-8543*

  2011cites this paper
• Is there a role for soluble guanylate cyclase stimulators in acute pulmonary embolism?

  2011cites this paper
• Antihypertensive effects exerted by enalapril in mild to moderate hypertension are not associated with changes in the circulating levels of nitric oxide-related markers

  2011cites this paper
• Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease.

  2011cites this paper
• Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle.

  2010cites this paper
• Effects of aerobic exercise on the blood pressure, oxidative stress and eNOS gene polymorphism in pre-hypertensive older people

  2010cites this paper
• BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats.

  2010influential citation
• Hemodynamic effects of inducible nitric oxide synthase inhibition combined with sildenafil during acute pulmonary embolism.

  2010cites this paper
• Soluble Guanylate Cyclase: Allosteric Activation and Redox Regulation

  2010cites this paper
• Assessment of vascular effects of tamoxifen and its metabolites on the rat perfused hindquarter vascular bed.

  2009cites this paper
• NO-independent, haem-dependent soluble guanylate cyclase stimulators.

  2009cites this paper
• Nitrite or sildenafil, but not BAY 41-2272, blunt acute pulmonary embolism-induced increases in circulating matrix metalloproteinase-9 and oxidative stress.

  2009cites this paper
• Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome.

  2008cites this paper
• A model of massive pulmonary embolism, development and characterization The pre-clinical steps forward and details of the progress

  2008cites this paper
• Lercanidipine reduces matrix metalloproteinase-2 activity and reverses vascular dysfunction in renovascular hypertensive rats.

  2008cites this paper
• Sildenafil improves the beneficial haemodynamic effects of intravenous nitrite infusion during acute pulmonary embolism.

  2008cites this paper
• Lercanidipine decreases vascular matrix metalloproteinase-2 activity and protects against vascular dysfunction in diabetic rats.

  2008cites this paper