Nanostructural insights into the dissolution behavior of Sr-doped hydroxyapatite

Abstract In this study, high-resolution transmission electron microscopy (HRTEM) was employed to characterize the nanostructure of strontium-substituted hydroxyapatite (Sr-HA) and its evolution following in vitro immersion in physiological solutions. HRTEM images showed that the substitution of Sr induced local distortions in the hydroxyapatite (HA) lattice: minor levels of edge dislocations were detected at low doping contents of Sr ions (1 at%); when the Sr content exceeded 10 at%, the density of grain boundaries increased notably and triple junctions were clearly observed. The dissolution of undoped HA was initiated at crystallite surfaces, whereas the dissolution of Sr-HA started around grain boundaries. Acicular nanocrystal reprecipitation was observed on grain surfaces immersed in simulated body fluid (SBF), while not in dilute hydrochloric acid (HCl). These findings suggest appropriate levels of Sr incorporation can introduce imperfections in the crystal structure of apatite and thus enhance its dissolution rate towards enhanced physicochemical performance in biomedical applications.

• Publication year

  2018

• Venue

  Journal of the European Ceramic Society

• Publication date

  2018-12-01

• Fields of study

  Materials Science, Physics

• Identifiers
  DOI 10.1016/j.jeurceramsoc.2018.07.056arXiv 1910.10610
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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