Systematic investigation of gastrointestinal diseases in China (SILC): validation of survey methodology

BackgroundSymptom-based surveys suggest that the prevalence of gastrointestinal diseases is lower in China than in Western countries. The aim of this study was to validate a methodology for the epidemiological investigation of gastrointestinal symptoms and endoscopic findings in China.MethodsA randomized, stratified, multi-stage sampling methodology was used to select 18 000 adults aged 18-80 years from Shanghai, Beijing, Xi'an, Wuhan and Guangzhou. Participants from Shanghai were invited to provide blood samples and undergo upper gastrointestinal endoscopy. All participants completed Chinese versions of the Reflux Disease Questionnaire (RDQ) and the modified Rome II questionnaire; 20% were also invited to complete the 36-item Short Form Health Survey (SF-36) and Epworth Sleepiness Scale (ESS). The psychometric properties of the questionnaires were evaluated statistically.ResultsThe study was completed by 16 091 individuals (response rate: 89.4%), with 3219 (89.4% of those invited) completing the SF-36 and ESS. All 3153 participants in Shanghai provided blood samples and 1030 (32.7%) underwent endoscopy. Cronbach's alpha coefficients were 0.89, 0.89, 0.80 and 0.91, respectively, for the RDQ, modified Rome II questionnaire, ESS and SF-36, supporting internal consistency. Factor analysis supported construct validity of all questionnaire dimensions except SF-36 psychosocial dimensions.ConclusionThis population-based study has great potential to characterize the relationship between gastrointestinal symptoms and endoscopic findings in China.

• Publication year

  2009

• Venue

  BMC Gastroenterology

• Publication date

  2009-11-19

• Fields of study

  Medicine

• Identifiers
  DOI 10.1186/1471-230X-9-86PMID 19925662PMCID 2788573
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• The Shanghai subcohort provided blood samples, and a subset underwent upper gastrointestinal endoscopy.

  Confidence 0.93

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• Factor analysis supported construct validity for all questionnaire dimensions except the SF-36 psychosocial dimensions.

  Confidence 0.95

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• Cronbach's alpha values of 0.89, 0.89, 0.80, and 0.91 support internal consistency for the Reflux Disease Questionnaire (RDQ), modified Rome II questionnaire, Epworth Sleepiness Scale (ESS), and 36-item Short Form Health Survey (SF-36), respectively.

  Confidence 0.97

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• A randomized, stratified, multi-stage sampling methodology was used to recruit 18,000 adults aged 18-80 years from Shanghai, Beijing, Xi'an, Wuhan, and Guangzhou.

  Confidence 0.98

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review

• 36-item short form health survey (sf-36)

  questionnaire, measurement instrument

  A 36-item health-related quality-of-life questionnaire administered to a subset of participants.

  Aliases: SF-36

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• construct validity

  psychometric property, validity measure

  The extent to which questionnaire dimensions align with the theoretical construct they are intended to measure.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• epworth sleepiness scale (ess)

  questionnaire, measurement instrument

  A questionnaire used to measure daytime sleepiness in the participant sample.

  Aliases: ESS

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• internal consistency

  psychometric property, reliability measure

  A reliability property indicating how consistently items within a questionnaire measure the same construct.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• modified rome ii questionnaire

  questionnaire, measurement instrument

  A Chinese-language symptom questionnaire adapted from Rome II criteria for gastrointestinal symptom assessment.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• randomized, stratified, multi-stage sampling methodology

  method

  A participant recruitment design that combines random selection, stratification, and multiple sampling stages across sites.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• reflux disease questionnaire (rdq)

  questionnaire, measurement instrument

  A Chinese-language questionnaire used to assess reflux-related symptoms in the survey.

  Aliases: RDQ

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review
• upper gastrointestinal endoscopy

  procedure, medical procedure

  An endoscopic procedure used to inspect the upper digestive tract in the Shanghai participants.

  Aliases: endoscopy

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) reviewq (76h6bfydm6) review

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