Protein Stabilisation by Compatible Solutes: Effect of Mannosylglycerate on Unfolding Thermodynamics and Activity of Ribonuclease A

No abstract is available for this paper.

• Publication year

  2003

• Venue

  ChemBioChem

• Publication date

  2003-08-04

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/cbic.200300574PMID 12898624
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sulfate anion stabilization of native ribonuclease A both by anion binding and by the Hofmeister effect

  2002cited by this paper
• Compatible solutes of organisms that live in hot saline environments.

  2002cited by this paper
• Comparative study of the thermostabilizing properties of mannosylglycerate and other compatible solutes on model enzymes

  2002cited by this paper
• Thermal unfolding of ribonuclease A in phosphate at neutral pH: Deviations from the two–state model

  2001cited by this paper
• Interpreting the effects of small uncharged solutes on protein-folding equilibria.

  2001cited by this paper
• Quantitative analysis of the effect of salt concentration on enzymatic catalysis.

  2001cited by this paper
• Cutinase unfolding and stabilization by trehalose and mannosylglycerate

  2001cited by this paper
• Life in extreme environments

  2001cited by this paper
• Thermostabilization of Proteins by Diglycerol Phosphate, a New Compatible Solute from the HyperthermophileArchaeoglobus fulgidus

  2000cited by this paper
• Extrinsic protein stabilization by the naturally occurring osmolytes beta-hydroxyectoine and betaine.

  1999cited by this paper
• Combined effect of the growth temperature and salinity of the medium on the accumulation of compatible solutes by Rhodothermus marinus and Rhodothermus obamensis

  1999cited by this paper
• Structure, thermostability, and conformational flexibility of hen egg-white lysozyme dissolved in glycerol.

  1999cited by this paper
• Extremophiles and their adaptation to hot environments

  1999cited by this paper
• Thermozymes: biotechnology and structure–function relationships

  1998cited by this paper
• An overview of the role and diversity of compatible solutes in Bacteria and Archaea.

  1998cited by this paper
• Activation and thermostabilization effects of cyclic 2,3-diphosphoglycerate on enzymes from the hyperthermophilic Methanopyrus kandleri

  1998cited by this paper
• Effect of osmolytes on the exchange rates of backbone amide protons in proteins.

  1998cited by this paper
• The thermodynamic mechanism of protein stabilization by trehalose.

  1997cited by this paper
• Stabilization of Enzymes against Thermal Stress and Freeze-Drying by Mannosylglycerate

  1997cited by this paper
• Mechanism of the stabilization of ribonuclease a by sorbitol: Preferential hydration is greater for the denatured than for the native protein

  1997cited by this paper
• Temperature dependence of the preferential interactions of ribonuclease a in aqueous co‐solvent systems: Thermodynamic analysis

  1997cited by this paper
• A general ribonuclease assay using methylene blue.

  1996cited by this paper
• Stability and folding of ultrastable proteins: eye lens crystalline and enzymes from thermophiles 1

  1996cited by this paper
• Hyperthermophile protein folding thermodynamics: differential scanning calorimetry and chemical denaturation of Sac7d.

  1996cited by this paper
• How Hofmeister ion interactions affect protein stability.

  1996cited by this paper
• Thermodynamics of denaturation of staphylococcal nuclease mutants: an intermediate state in protein folding

  1996cited by this paper
• Accumulation of Mannosylglycerate and Di-myo-Inositol-Phosphate by Pyrococcus furiosus in Response to Salinity and Temperature

  1995cited by this paper
• Effects of a naturally occurring compatible osmolyte on the internal dynamics of ribonuclease A.

  1995cited by this paper
• An osmolyte effect on the heat capacity change for protein folding.

  1995cited by this paper
• The peptide backbone plays a dominant role in protein stabilization by naturally occurring osmolytes.

  1995cited by this paper
• Mechanism-based strategies for protein thermostabilization.

  1993cited by this paper
• The control of protein stability and association by weak interactions with water: how do solvents affect these processes?

  1993cited by this paper
• Increased thermal stability of proteins in the presence of naturally occurring osmolytes.

  1992cited by this paper
• Heat capacity of proteins. II. Partial molar heat capacity of the unfolded polypeptide chain of proteins: protein unfolding effects.

  1990cited by this paper
• Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants.

  1988cited by this paper
• Thermodynamic and kinetic examination of protein stabilization by glycerol.

  1981cited by this paper
• The stabilization of proteins by sucrose.

  1981cited by this paper
• Microbial water stress.

  1976cited by this paper
• Isoelectric points and conformation of proteins. II. Isoelectric focusing of alpha-chymotrypsin and its inactive derivative.

  1971cited by this paper
• Isoelectric points and conformation of proteins. I. Effect of urea on the behavior of some proteins in isoelectric focusing.

  1971cited by this paper
• On the conformational stability of globular proteins. The effects of various electrolytes and nonelectrolytes on the thermal ribonuclease transition.

  1965cited by this paper

• DeepSTABp: A Deep Learning Approach for the Prediction of Thermal Protein Stability

  2023cites this paper
• Effects of Crowding and Cosolutes on Biomolecular Function at Extreme Environmental Conditions.

  2023cites this paper
• Glycopeptide antibiotic drug stability in aqueous solution

  2022cites this paper
• Differential effect of polyol and sugar osmolytes on the refolding of homologous alpha amylases: A comparative study.

  2021cites this paper
• The first study on the impact of osmolytes in whole cells of high temperature-adapted microorganisms.

  2019cites this paper
• Production of the compatible solute α-d-glucosylglycerol by metabolically engineered Corynebacterium glutamicum

  2018cites this paper
• Multifactorial level of extremostability of proteins: can they be exploited for protein engineering?

  2017cites this paper
• Synthesis of Mannosylglycerate Derivatives as Immunostimulating Agents

  2017cites this paper
• Insights into the biochemical strategies of adaptation to heat stress in the hyperthermophilic archaeon Pyrococcus furiosus

  2015cites this paper
• A unique glyceryl diglycoside identified in the thermophilic, radiation-resistant bacterium Rubrobacter xylanophilus

  2015cites this paper
• Industrial Production of the Cell Protectant Ectoine: Protection Mechanisms, Processes, and Products

  2014cites this paper
• Stability of Lysozyme in Aqueous Extremolyte Solutions during Heat Shock and Accelerated Thermal Conditions

  2014influential citation
• The biosynthesis of trehalose and sugar-glycerate compatible solutes in organisms that live in hot and saline environments

  2013cites this paper
• Innovative strategies for stabilization of therapeutic peptides in aqueous formulations

  2012cites this paper
• Diversity, biological roles and biosynthetic pathways for sugar-glycerate containing compatible solutes in bacteria and archaea.

  2011cites this paper
• Glycosides as compatible solutes: biosynthesis and applications.

  2011cites this paper
• Organic compatible solutes of prokaryotes that thrive in hot environments: the importance of ionic compounds for thermostabilization

  2011cites this paper
• Structural requirements for efficient prion protein conversion: Cofactors may promote a conversion-competent structure for PrPC

  2010cites this paper
• Glucosylglycerol and glucosylglycerate as enzyme stabilizers

  2010cites this paper
• Saccharomyces cerevisiae for the production of mannosylglycerate-a yeast model for assessing its application in protein stabilization

  2010cites this paper
• Structural requirements for efficient prion protein conversion

  2010cites this paper
• Biocatalytic process for production of α-glucosylglycerol using sucrose phosphorylase.

  2010cites this paper
• Single-step enzymatic synthesis of (R)-2-O-alpha-D-glucopyranosyl glycerate, a compatible solute from micro-organisms that functions as a protein stabiliser.

  2009cites this paper
• Design of new enzyme stabilizers inspired by glycosides of hyperthermophilic microorganisms.

  2008cites this paper
• Structure of mannosyl-3-phosphoglycerate phosphatase from Pyrococcus horikoshii.

  2008cites this paper
• Compatible solutes from hyperthermophiles improve the quality of DNA microarrays

  2007cites this paper
• Compatible solutes of microorganisms from hot, marine environments:

  2007cites this paper
• The Physiological Role, Biosynthesis, and Mode of Action of Compatible Solutes from (Hyper)Thermophiles

  2007cites this paper
• Role in Protein Stabilization

  2007cites this paper
• Thermodynamic perspectives on the molecular mechanisms providing protein adsorption resistance that include protein-surface interactions.

  2006cites this paper
• Structural dissection and high-throughput screening of mannosylglycerate synthase

  2005cites this paper
• EN MIKROKALORIMETRISK UNDERSØGELSE AF SOLUTTERS EFFEKT PÅ DEN TERMISK INDUCEREDE, IRREVERSIBLE DENATURERING AF BACILLUS HALMAPALUS α-AMYLASE

  2005cites this paper
• Cloning and Expression of Islandisin, a New Thermostable Subtilisin from Fervidobacterium islandicum, in Escherichia coli

  2005cites this paper
• Osmoadaptation and osmoregulation in archaea: update 2004.

  2004cites this paper
• Protein Stabilization by Osmolytes from Hyperthermophiles

  2004cites this paper
• A Gene from the Mesophilic Bacterium Dehalococcoides ethenogenes Encodes a Novel Mannosylglycerate Synthase

  2004cites this paper